OMIA 000496-9796 : Hyperbilirubinaemia I in Equus caballus |
In other species:
sheep
,
Bolivian squirrel monkey
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers):
143500 (trait)
,
191740 (gene)
,
218800 (trait)
Mendelian trait/disorder:
yes
Considered a defect:
yes
Key variant known:
no
Cross-species summary:
Bilirubin is an orange bile pigment produced by the breakdown of haem and reduction of biliverdinin. An excess of bilirubin in the blood, resulting from a defect in uptake of organic anions by the liver, is called hyperbilirubinaemia I or Gilbert's syndrome. Another anion unable to be taken up by affected livers is phylloerythrin, a metabolite of chlorophyll. The resultant high blood levels of phylloerythrin result in photosensitive dermatitis. [Researched by Philippa Beard]
Reference
1995 | Deprez, P., Sustronck, B., Vanloon, G., Muylle, E. : | |
Persistent hyperbilirubinemia in a horse - a case report [Dutch] Vlaams Diergeneeskundig Tijdschrift 64:212-215, 1995. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005