OMIA:000496 : Hyperbilirubinaemia I
Categories: Homeostasis / metabolism phene
Links to MONDO diseases: No links.
Cross-species summary: Bilirubin is an orange bile pigment produced by the breakdown of haem and reduction of biliverdinin. An excess of bilirubin in the blood, resulting from a defect in uptake of organic anions by the liver, is called hyperbilirubinaemia I or Gilbert's syndrome. Another anion unable to be taken up by affected livers is phylloerythrin, a metabolite of chlorophyll. The resultant high blood levels of phylloerythrin result in photosensitive dermatitis. [Researched by Philippa Beard]
- Created by Frank Nicholas on 03 May 2005
- Changed by Imke Tammen2 on 14 Oct 2022