OMIA:000496 : Hyperbilirubinaemia I

Categories: Homeostasis / metabolism phene

Possible human homologues (MIM numbers): 143500 (trait) , 191740 (gene) , 218800 (trait)

Links to MONDO diseases: No links.

Cross-species summary: Bilirubin is an orange bile pigment produced by the breakdown of haem and reduction of biliverdinin. An excess of bilirubin in the blood, resulting from a defect in uptake of organic anions by the liver, is called hyperbilirubinaemia I or Gilbert's syndrome. Another anion unable to be taken up by affected livers is phylloerythrin, a metabolite of chlorophyll. The resultant high blood levels of phylloerythrin result in photosensitive dermatitis. [Researched by Philippa Beard]

Species in which this phene is found:
horse (Equus caballus)
sheep (Ovis aries)
Bolivian squirrel monkey (Saimiri boliviensis)

Edit History

  • Created by Frank Nicholas on 03 May 2005
  • Changed by Imke Tammen2 on 14 Oct 2022