OMIA 000621-9823 : Malignant hyperthermia in Sus scrofa

In other species: domestic cat , cattle , dog , horse , rabbit , deer , turkey

Possibly relevant human trait(s) and/or gene(s) (MIM number): 145600

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: yes

Key variant known: yes

Year key variant first reported: 1991

Cross-species summary: A progressive increase in body temperature, muscle rigidity and metabolic acidosis, leading to rapid death.

Species-specific name: Porcine Stress Syndrome

Species-specific symbol: PSS

Species-specific description: In pigs, malignant hyperthermia (MH) leads to rapid post-mortem changes in muscle, resulting in pale soft exudative (PSE) meat. MH can be triggered by a minor stress, such as loading, transport, sexual intercourse, high ambient temperature, or exposure to the anaesthetic halothane. Susceptibility to halothane-induced MH is an autosomal recessive trait in pigs. Together, sudden death syndrome and PSE constitute porcine stress syndrome (PSS), which became a major economic problem in many countries in the 1970s, as indicated by the number of references in the list below. In part, the increasing problem of PSS was due to strong selection for increased leanness, which is associated with susceptibility to PSS.

Inheritance: Autosomal recessive inheritance (with some incomplete penetrance) of malignant hyperthermia induced by halothane inhalation was reported by Ollivier et al., 1975; Minkema et al., 1977; and Smith and Bampton, 1978).

Mapping: Building on reports of association between halothane-induced malignant hyperthermia (Hal) and various gene markers, Andresen and Jensen (1977) showed that Hal is linked to the gene encoding phosphohexose isomerase (PHI), now called glucose phosphate isomerase (GPI). By the mid-1980s, this linkage group had been expanded to comprise six loci, including Hal (Archibald and Imlah, 1985). Using in situ hybridisation of a clone containing the porcine GPI gene, Davies et al. (1988) showed that the Hal linkage group maps to chromosome SSC6p12-q22. Also using in situ hybridisation, Harbitz et al. (1990) physically mapped the RYR1 gene (then called the calcium release channel [CRC] gene) to chromosome SSC6p11-q21.

Molecular basis: The molecular basis of MH in pigs was discovered via identification of a strong candidate gene, namely RYR1, that encodes a calcium release channel of skeletal muscle sarcoplasmic reticulum. When it was shown that this candidate gene mapped very closely to MH in pigs and in humans, the race was on to clone and sequence the RYR1 gene. The race was won by a Canadian research team led by David MacLennan (Fujii et al., 1991) who showed that MH is due to a base substitution (C-T) in the 1843rd nucleotide of the RYR1 gene. The base substitution causes an amino-acid substitution (arginine - cysteine) in the 615th position of the calcium release channel, resulting in altered calcium flow. It is remarkable that the smallest possible change (a single base-substitution) leading to a single amino-acid-substitution in a very large molecule (comprising 5,035 amino acids) can have caused a disorder that was a major financial burden for the global pig industry for several decades.

Interestingly, Bates et al. (2012) reported that "A proportion of pigs normal for RYR1 did exhibit limb rigidity during halothane gas challenge, and subsequently tended to have lower 45 min pH and greater longissimus muscle fluid loss post harvest." This suggests that the RYR1 locus is not the only factor determining reaction to halothane.

Genetic testing: Various PCR genotyping tests have been devised, all based on detection of an RFLP resulting from the causative base substitution. Over a roughly ten-year period, these tests enabled the harmful allele to be removed from most pig populations throughout the world.

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
RYR1 ryanodine receptor 1 (skeletal) Sus scrofa 6 NC_010448.4 (47339759..47458457) RYR1 Homologene, Ensembl, NCBI gene

Variants

By default, variants are sorted chronologically by year of publication, to provide a historical perspective.

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Breed(s) Variant Phenotype Gene Allele Type of Variant Reference Sequence Chr. g. or m. c. or n. p. Verbal Description EVA ID Year Published PubMed ID(s) Acknowledgements
Malignant hyperthermia RYR1 missense Sscrofa10.2 6 g.42868983C>T c.1423C>T p.R475C 1991 1862346 Variant coordinates obtained from or confirmed by EBI's Some Effect Predictor (VEP) tool

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2018 Johannsen, S., Türkmeneli, I., Isbary, S., Roewer, N., Schuster, F. :
Ultrasound Elastography for Rapid, Real-time Detection of Localized Muscular Reaction in Malignant Hyperthermia-susceptible Pigs. Anesthesiology :, 2018. Pubmed reference: 30204593. DOI: 10.1097/ALN.0000000000002424.
Oliván, M., González, J., Bassols, A., Díaz, F., Carreras, R., Mainau, E., Arroyo, L., Peña, R., Potes, Y., Coto-Montes, A., Hollung, K., Velarde, A. :
Effect of sex and RYR1 gene mutation on the muscle proteomic profile and main physiological biomarkers in pigs at slaughter. Meat Sci 141:81-90, 2018. Pubmed reference: 29621665. DOI: 10.1016/j.meatsci.2018.03.018.
2017 Salas, R.C., Mingala, C.N. :
Genetic Factors Affecting Pork Quality: Halothane and Rendement Napole Genes. Anim Biotechnol 28:148-155, 2017. Pubmed reference: 27854153. DOI: 10.1080/10495398.2016.1243550.
2016 Ciepielewski, Z.M., Stojek, W., Borman, A., Myślińska, D., Pałczyńska, P., Kamyczek, M. :
The effects of ryanodine receptor (RYR1) mutation on natural killer cell cytotoxicity, plasma cytokines and stress hormones during acute intermittent exercise in pigs. Res Vet Sci 105:77-86, 2016. Pubmed reference: 27033913. DOI: 10.1016/j.rvsc.2016.01.012.
Popovski, Z.T., Tanaskovska, B., Miskoska-Milevska, E., Andonov, S., Domazetovska, S. :
Associations of biochemical changes and maternal traits with mutation 1843 (C>T) in the RYR1 gene as a common cause for porcine stress syndrome. Balkan J Med Genet 19:75-80, 2016. Pubmed reference: 28289592. DOI: 10.1515/bjmg-2016-0039.
2014 Alves, L.R., Antunes, R.C., Andrade, R.B., Storti, A.A., Reis, S.L., Carrazza, L.G., Osava, C.F., Costa, N.V. :
Effect of the halothane genotype on intramuscular fat deposition in swine. Genet Mol Res 13:363-70, 2014. Pubmed reference: 24535863. DOI: 10.4238/2014.January.21.4.
Schuster, F., Johannsen, S., Moegele, S., Metterlein, T., Roewer, N., Anetseder, M. :
The effect of succinylcholine on malignant hyperthermia events in susceptible swine. BMC Anesthesiol 14:14, 2014. Pubmed reference: 24606822. DOI: 10.1186/1471-2253-14-14.
2013 Ciepielewski, Z.M., Stojek, W., Glac, W., Myślińska, D., Kwaczyńska, A., Kamyczek, M. :
The effects of ryanodine receptor 1 (RYR1) mutation on plasma cytokines and catecholamines during prolonged restraint in pigs. Vet Immunol Immunopathol :, 2013. Pubmed reference: 24176615. DOI: 10.1016/j.vetimm.2013.10.001.
Ciepielewski, Z.M., Stojek, W., Glac, W., Wrona, D. :
Restraint effects on stress-related hormones and blood natural killer cell cytotoxicity in pigs with a mutated ryanodine receptor. Domest Anim Endocrinol 44:195-203, 2013. Pubmed reference: 23571007. DOI: 10.1016/j.domaniend.2013.02.003.
Schütte, J.K., Schäfer, U., Becker, S., Oldewurtel, C., Starosse, A., Singler, P., Richard, A., Wappler, F., Gerbershagen, M.U. :
3,4-Methylenedioxymethamphetamine induces a hyperthermic and hypermetabolic crisis in pigs with and without a genetic disposition for malignant hyperthermia. Eur J Anaesthesiol 30:29-37, 2013. Pubmed reference: 23138574. DOI: 10.1097/EJA.0b013e32835a1127.
2012 Bates, R.O., Doumit, M.E., Raney, N.E., Helman, E.E., Ernst, C.W. :
Association of halothane sensitivity with growth and meat quality in pigs. Animal 6:1537-42, 2012. Pubmed reference: 23031527. DOI: 10.1017/S1751731112000134.
Gerbershagen, M.U., Missler, G., Schütte, J.K., Starosse, A., Graf, B.M., Wappler, F., Zink, W. :
3,4-Methylenedioxymethamphetamine (Ecstasy) increases the sensitivity of the contractile apparatus to calcium ions in both malignant hyperthermia-susceptible and normal skeletal muscle fibres. Eur J Anaesthesiol 29:42-9, 2012. Pubmed reference: 22089516. DOI: 10.1097/EJA.0b013e32834d9427.
Pastoret, S., Ameels, H., Bossiroy, F., Decreux, A., De Longueville, F., Thomas, A., Desmecht, D. :
Detection of disease resistance and susceptibility alleles in pigs using oligonucleotide microarray hybridization. J Vet Diagn Invest 24:479-88, 2012. Pubmed reference: 22529114. DOI: 10.1177/1040638712442878.
Vandenhaute, E., Culot, M., Gosselet, F., Dehouck, L., Godfraind, C., Franck, M., Plouët, J., Cecchelli, R., Dehouck, M.P., Ruchoux, M.M. :
Brain pericytes from stress-susceptible pigs increase blood-brain barrier permeability in vitro. Fluids Barriers CNS 9:11, 2012. Pubmed reference: 22569151. DOI: 10.1186/2045-8118-9-11.
Weschenfelder, A.V., Torrey, S., Devillers, N., Crowe, T., Bassols, A., Saco, Y., Piñeiro, M., Saucier, L., Faucitano, L. :
Effects of trailer design on animal welfare parameters and carcass and meat quality of three Pietrain crosses being transported over a long distance. J Anim Sci 90:3220-31, 2012. Pubmed reference: 22966081. DOI: 10.2527/jas.2012-4676.
2011 Cherel, P., Pires, J., Glenisson, J., Milan, D., Iannuccelli, N., Herault, F., Damon, M., Le Roy, P. :
Joint analysis of quantitative trait loci and major-effect causative mutations affecting meat quality and carcass composition traits in pigs. BMC Genet 12:76, 2011. Pubmed reference: 21875434. DOI: 10.1186/1471-2156-12-76.
Fiege, M., Weisshorn, R., Kolodzie, K., Wappler, F., Gerbershagen, M.U. :
Effects of theophylline on anesthetized malignant hyperthermia-susceptible pigs. J Biomed Biotechnol 2011:937479, 2011. Pubmed reference: 22131820. DOI: 10.1155/2011/937479.
Krischek, C., Natter, R., Wigger, R., Wicke, M. :
Adenine nucleotide concentrations and glycolytic enzyme activities in longissimus muscle samples of different pig genotypes collected before and after slaughter. Meat Sci 89:217-20, 2011. Pubmed reference: 21592677. DOI: 10.1016/j.meatsci.2011.04.022.
Metterlein, T., Schuster, F., Kranke, P., Hager, M., Roewer, N., Anetseder, M. :
Magnesium does not influence the clinical course of succinylcholine-induced malignant hyperthermia. Anesth Analg 112:1174-8, 2011. Pubmed reference: 21474662. DOI: 10.1213/ANE.0b013e31821263d6.
Metterlein, T., Schuster, F., Palmer, E., Roewer, N., Anetseder, M. :
Succinylcholine in malignant hyperthermia: evaluation of a novel in vivo model. Muscle Nerve 44:213-6, 2011. Pubmed reference: 21607984. DOI: 10.1002/mus.22025.
Schütte, J.K., Becker, S., Burmester, S., Starosse, A., Lenz, D., Kröner, L., Wappler, F., Gerbershagen, M.U. :
Comparison of the therapeutic effectiveness of a dantrolene sodium solution and a novel nanocrystalline suspension of dantrolene sodium in malignant hyperthermia normal and susceptible pigs. Eur J Anaesthesiol 28:256-64, 2011. Pubmed reference: 21513076.
Shirali, M., Doeschl-Wilson, A., Knap, P.W., Duthie, C., Kanis, E., van Arendonk, J.A., Roehe, R. :
Nitrogen excretion at different stages of growth and its association with production traits in growing pigs. J Anim Sci :, 2011. Pubmed reference: 22178856. DOI: 10.2527/jas.2011-4547.
Silveira, A.C., Freitas, P.F., César, A.S., Cesar, A.S., Antunes, R.C., Guimarães, E.C., Batista, D.F., Torido, L.C. :
Influence of the halothane gene (HAL) on pork quality in two commercial crossbreeds. Genet Mol Res 10:1479-89, 2011. Pubmed reference: 21823098.
2010 Bina, S., Capacchione, J., Muldoon, S., Bayarsaikhan, M., Bunger, R. :
Lymphocyte-based determination of susceptibility to malignant hyperthermia: a pilot study in swine. Anesthesiology 113:917-24, 2010. Pubmed reference: 20823761. DOI: 10.1097/ALN.0b013e3181ee2cd0.
Cherel, P., Glénisson, J., Figwer, P., Pires, J., Damon, M., Franck, M., Le Roy, P. :
Updated estimates of HAL n and RN- effects on pork quality: fresh and processed loin and ham. Meat Sci 86:949-54, 2010. Pubmed reference: 20826068. DOI: 10.1016/j.meatsci.2010.07.022.
do Carmo, P.L., Zapata-Sudo, G., Trachez, M.M., Antunes, F., Guimarães, S.E., Debom, R., Rizzi, M.D., Sudo, R.T. :
Intravenous administration of azumolene to reverse malignant hyperthermia in swine. J Vet Intern Med 24:1224-8, 2010. Pubmed reference: 20584138. DOI: 10.1111/j.1939-1676.2010.0556.x.
2009 Laville, E., Sayd, T., Terlouw, C., Blinet, S., Pinguet, J., Fillaut, M., Glénisson, J., Chérel, P. :
Differences in pig muscle proteome according to HAL genotype: implications for meat quality defects. J Agric Food Chem 57:4913-23, 2009. Pubmed reference: 19449875. DOI: 10.1021/jf900286x.
Zhang, S., Knight, TJ., Stalder, KJ., Goodwin, RN., Lonergan, SM., Beitz, DC. :
Effects of breed, sex and halothane genotype on fatty acid composition of triacylglycerols and phospholipids in pork longissimus muscle. J Anim Breed Genet 126:259-68, 2009. Pubmed reference: 19630876. DOI: 10.1111/j.1439-0388.2008.00782.x.
2008 Barbut, S., Sosnicki, A.A., Lonergan, S.M., Knapp, T., Ciobanu, D.C., Gatcliffe, L.J., Huff-Lonergan, E., Wilson, E.W. :
Progress in reducing the pale, soft and exudative (PSE) problem in pork and poultry meat. Meat Sci 79:46-63, 2008. Pubmed reference: 22062597. DOI: 10.1016/j.meatsci.2007.07.031.
Bina, S., Muldoon, S., Bünger, R. :
Effects of ryanodine on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis. Eur J Anaesthesiol 25:48-57, 2008. Pubmed reference: 17686208. DOI: 10.1017/S0265021507001238.
Jiang, D., Chen, W., Xiao, J., Wang, R., Kong, H., Jones, PP., Zhang, L., Fruen, B., Chen, SR. :
Reduced threshold for luminal Ca2+ activation of RyR1 underlies a causal mechanism of porcine malignant hyperthermia. J Biol Chem 283:20813-20, 2008. Pubmed reference: 18505726. DOI: 10.1074/jbc.M801944200.
Kadarmideen, HN. :
Biochemical, ECF18R, and RYR1 gene polymorphisms and their associations with osteochondral diseases and production traits in pigs. Biochem Genet 46:41-53, 2008. Pubmed reference: 17943437. DOI: 10.1007/s10528-007-9127-5.
Li, LA., Xia, D., Wei, S., Li, X., Parvizi, N., Zhao, RQ. :
Diminished expression of ACTH signaling proteins and steroidogenic limiting factors in adrenocortical cells isolated from halothane nn pigs. Domestic Animal Endocrinology 35:1-7, 2008. Pubmed reference: 18304776. DOI: 10.1016/j.domaniend.2007.12.005.
Ritter, MJ., Ellis, M., Hollis, GR., McKeith, FK., Orellana, DG., Van Genugten, P., Curtis, SE., Schlipf, JM. :
Frequency of the HAL-1843 mutation of the ryanodine receptor gene in dead and nonambulatory-noninjured pigs on arrival at the packing plant. J Anim Sci 86:511-4, 2008. Pubmed reference: 18073280. DOI: 10.2527/jas.2007-0329.
2007 Cechová, M., Wolf, J., Trcka, P. :
Impact of RYR1 genotype of Piétrain boars on litter traits of Czech Large White x Czech Landrace crossbred sows. J Anim Breed Genet 124:86-93, 2007. Pubmed reference: 17488359. DOI: 10.1111/j.1439-0388.2007.00640.x.
Franck, M., Figwer, P., Godfraind, C., Poirel, MT., Khazzaha, A., Ruchoux, MM. :
Could the pale, soft, and exudative condition be explained by distinctive histological characteristics? J Anim Sci 85:746-53, 2007. Pubmed reference: 17040940. DOI: 10.2527/jas.2006-190.
Jennen, D.G., Brings, A.D., Liu, G., Jüngst, H., Tholen, E., Jonas, E., Tesfaye, D., Schellander, K., Phatsara, C. :
Genetic aspects concerning drip loss and water-holding capacity of porcine meat. J Anim Breed Genet 124 Suppl 1:2-11, 2007. Pubmed reference: 17988245. DOI: 10.1111/j.1439-0388.2007.00681.x.
Murayama, T., Oba, T., Hara, H., Wakebe, K., Ikemoto, N., Ogawa, Y. :
Postulated role of interdomain interaction between regions 1 and 2 within type 1 ryanodine receptor in the pathogenesis of porcine malignant hyperthermia. Biochem J 402:349-57, 2007. Pubmed reference: 17107340. DOI: 10.1042/BJ20061040.
Rosenberg, H., Davis, M., James, D., Pollock, N., Stowell, K. :
Malignant hyperthermia. Orphanet J Rare Dis 2:21, 2007. Pubmed reference: 17456235. DOI: 10.1186/1750-1172-2-21.
Schuster, F., Metterlein, T., Negele, S., Gardill, A., Schwemmer, U., Roewer, N., Anetseder, M. :
Intramuscular injection of sevoflurane detects malignant hyperthermia predisposition in susceptible pigs. Anesthesiology 107:616-20, 2007. Pubmed reference: 17893458. DOI: 10.1097/01.anes.0000281915.85577.1a.
Shen, QW., Underwood, KR., Means, WJ., McCormick, RJ., Du, M. :
The halothane gene, energy metabolism, adenosine monophosphate-activated protein kinase, and glycolysis in postmortem pig longissimus dorsi muscle. J Anim Sci 85:1054-61, 2007. Pubmed reference: 17202397. DOI: 10.2527/jas.2006-114.
Stinckens, A., Van den Maagdenberg, K., Luyten, T., Georges, M., De Smet, S., Buys, N. :
The RYR1 g.1843C>T mutation is associated with the effect of the IGF2 intron3-g.3072G>A mutation on muscle hypertrophy. Anim Genet 38:67-71, 2007. Pubmed reference: 17257191. DOI: 10.1111/j.1365-2052.2006.01558.x.
Ta, TA., Pessah, IN. :
Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95). Neurotoxicology 28:770-9, 2007. Pubmed reference: 17023049. DOI: 10.1016/j.neuro.2006.08.007.
Zhang, S., Knight, TJ., Stalder, KJ., Goodwin, RN., Lonergan, SM., Beitz, DC. :
Effects of breed, sex, and halothane genotype on fatty acid composition of pork longissimus muscle. J Anim Sci 85:583-91, 2007. Pubmed reference: 17060410. DOI: 10.2527/jas.2006-239.
2006 Allison, CP., Marr, AL., Berry, NL., Anderson, DB., Ivers, DJ., Richardson, LF., Keffaber, K., Johnson, RC., Doumit, ME. :
Effects of halothane sensitivity on mobility status and blood metabolites of HAL-1843-normal pigs after rigorous handling. J Anim Sci 84:1015-21, 2006. Pubmed reference: 16543580.
Bina, S., Cowan, G., Karaian, J., Muldoon, S., Mongan, P., Bunger, R. :
Effects of caffeine, halothane, and 4-chloro-m-cresol on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis. Anesthesiology 104:90-100, 2006. Pubmed reference: 16394695.
Khazzaka, A., Figwer, P., Poirel, M. T., Serrar, M., Franck, M. :
Hsp70 response in pigs is affected by their Halothane genotypes after heat stress Journal of Thermal Biology 31:605-610, 2006.
Schuster, F., Schöll, H., Hager, M., Müller, R., Roewer, N., Anetseder, M. :
The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs. Anesth Analg 102:468-72, 2006. Pubmed reference: 16428544. DOI: 10.1213/01.ane.0000189553.57833.11.
Stojek, W., Borman, A., Glac, W., Baracz-Jóźwik, B., Witek, B., Kamyczek, M., Tokarski, J. :
Stress-induced enhancement of activity of lymphocyte lysosomal enzymes in pigs of different stress-susceptibility. J Physiol Pharmacol 57 Suppl 8:61-72, 2006. Pubmed reference: 17242473.
2005 Allison, CP., Johnson, RC., Doumit, ME. :
The effects of halothane sensitivity on carcass composition and meat quality in HAL-1843-normal pigs. J Anim Sci 83:671-8, 2005. Pubmed reference: 15705764.
Fiege, M., Wappler, F., Weisshorn, R., Gerbershagen, MU., Kolodzie, K., Schulte am Esch, J. :
Phosphodiesterase-III-inhibition with amrinone leads to contracture development in skeletal muscle preparations of malignant hyperthermia susceptible swine. Eur J Anaesthesiol 22:283-8, 2005. Pubmed reference: 15892406.
Lechniak, D., Szczepankiewicz, D., Kauss, D., Szulc, J., Szydłowski, M. :
IVM media, oocyte diameter and donor genotype at RYR1 locus in relation to the incidence of porcine diploid oocytes after maturation in vitro. Theriogenology 64:202-12, 2005. Pubmed reference: 15935853. DOI: 10.1016/j.theriogenology.2004.11.019.
2004 Brunson, DB., Hogan, KJ. :
Malignant hyperthermia: a syndrome not a disease. Vet Clin North Am Small Anim Pract 34:1419-33, 2004. Pubmed reference: 15474681. DOI: 10.1016/j.cvsm.2004.05.010.
Gallant, EM., Hart, J., Eager, K., Curtis, S., Dulhunty, AF. :
Caffeine sensitivity of native RyR channels from normal and malignant hyperthermic pigs: effects of a DHPR II-III loop peptide. Am J Physiol Cell Physiol 286:C821-30, 2004. Pubmed reference: 14644774. DOI: 10.1152/ajpcell.00311.2003.
Gerbershagen, MU., Fiege, M., Weisshorn, R., Kolodzie, K., Wappler, F. :
[Theophylline induces contractures in porcine skeletal muscle preparations with the disposition to malignant hyperthermia] Anasthesiol Intensivmed Notfallmed Schmerzther 39:147-52, 2004. Pubmed reference: 15042504. DOI: 10.1055/s-2004-814328.
Gerbershagen, MU., Wappler, F., Fiege, M., Weisshorn, R., Kolodzie, K., Schulte am Esch, J. :
[Is a presymptomatic malignant hyperthermia in-vitro diagnosis with 4-chloro-3-ethyl phenol possible? A study using porcine skeletal preparations] Anasthesiol Intensivmed Notfallmed Schmerzther 39:81-6, 2004. Pubmed reference: 14767797. DOI: 10.1055/s-2004-817676.
Omelka, R., Vasícek, D., Martiniaková, M., Bulla, J., Bauerová, M. :
Simultaneous detection of malignant hyperthermia and genetic predisposition for improved litter size in pigs by multiplex PCR-RFLP. Folia Biol (Krakow) 52:113-5, 2004. Pubmed reference: 15521658.
2003 Fiege, M., Wappler, F., Weisshorn, R., Gerbershagen, MU., Kolodzie, K., Schulte am Esch, J. :
In vitro and in vivo effects of the phosphodiesterase-III inhibitor enoximone on malignant hyperthermia-susceptible swine. Anesthesiology 98:944-9, 2003. Pubmed reference: 12657857.
Fiege, M., Wappler, F., Weisshorn, R., Gerbershagen, MU., Menge, M., Schulte am Esch, J. :
Induction of malignant hyperthermia in susceptible swine by 3,4-methylenedioxymethamphetamine ("ecstasy"). Anesthesiology 99:1132-6, 2003. Pubmed reference: 15220814.
Gerbershagen, M.U., Wappler, F., Fiege, M., Kolodzie, K., Weisshorn, R., Szafarczyk, W., Kudlik, C., Schulte, Am, Esch, J. :
Effects of a 5HT(2) receptor agonist on anaesthetized pigs susceptible to malignant hyperthermia British Journal of Anaesthesia 91:281-4, 2003. Pubmed reference: 12878630.
Moelich, E.I., Hoffman, L.C., Conradie, P.J. :
Sensory and functional meat quality characteristics of pork derived from three halothane genotypes Meat Science 63:333-338, 2003.
2002 Apple, J.K., Maxwell, C.V., Stivarius, M.R., Rakes, L.K., Johnson, Z.B. :
Effects of dietary magnesium and halothane genotype on performance and carcass traits of growing-finishing swine Livestock Production Science 76:103-113, 2002.
Costa, L.N., Lo, Fiego, D.P., Dall'Olio, S., Davoli, R., Russo, V. :
Combined effects of pre-slaughter treatments and lairage time on carcass and meat quality in pigs of different halothane genotype Meat Science 61:41-47, 2002.
Fabrega, E., Diestre, A., Carrion, D., Font, J., Manteca, X. :
Effect of the halothane gene on pre-slaughter mortality in two Spanish commercial pig abattoirs Animal Welfare 11:449-452, 2002.
Fabrega, E., Manteca, X., Font, J., Gispert, M., Carrion, D., Velarde, A., Ruiz-de-la-Torre, J.L., Diestre, A. :
Effects of halothane gene and pre-slaughter treatment on meat quality and welfare from two pig crosses Meat Science 62:463-472, 2002.
Fazarinc, G., Candek-Potokar, M., Ursic, M., Vrecl, M., Pogacnik, A. :
Giant muscle fibres in pigs with different Ryr1 genotype Anatomia, Histologia, Embryologia: Veterinary Medicine Series C 31:367-371, 2002.
Gerbershagen, M.U., Wappler, E., Fiege, M., Weisshorn, R., Alberts, P.A., von, Breunig, E., Esch, J.S.A. :
In vitro effects of 4-chloro-3-ethylphenol in skeletal muscle preparations from malignant hyperthermia susceptible and normal swine European Journal of Anaesthesiology 19:135-140, 2002. Pubmed reference: 11999597.
Lahucky, R., Baulain, U., Henning, M., Demo, P., Krska, P., Liptaj, T. :
In vitro P-31 NMR studies on biopsy skeletal muscle samples compared with meat quality of normal and heterozygous malignant hyperthermia pigs Meat Science 61:233-241, 2002.
Lee, S.H., Cho, K.K., Kang, S.K., Kim, C.W., Park, H.C., Choy, Y.H., Choi, Y.J. :
Detection of pigs resistant to post-weaning diarrhoea, oedema disease and porcine stress syndrome by allele-specific polymerase chain reaction Animal Genetics 33:237-239, 2002. Pubmed reference: 12030936.
Liou, Y.M., Jiang, M.J., Wu, M.C. :
Changes in thiol reactivity and extractability of myofibril bound cardiac troponin C in porcine malignant hyperthermia Journal of Biochemistry 132:317-325, 2002. Pubmed reference: 12153731.
Martins-Wess, F., Voss-Nemitz, R., Drogemuller, C., Brenig, B., Leeb, T. :
Construction of a 1.2-Mb BAC/PAC contig of the porcine gene RYR1 region on SSC 6q1.2 and comparative analysis with HSA 19q13.13 Genomics 80:416-422, 2002. Pubmed reference: 12376096.
Nurnberg, K., Kuchenmeister, U., Jakstadt, M., Ender, K., Kuhn, G., Nurnberg, G., Grune, T. :
Compositional changes in muscle of malignant hyperthermia-susceptible pigs due to postmortem alterations in lipid metabolism, lipid peroxidation and protein oxidation Journal of Food Composition & Analysis 15:283-292, 2002.
Youssao, I.A.K., Verleyen, V., Leroy, P.L. :
Prediction of carcass lean content by real-time ultrasound in Pietrain and negative stress Pietrain Animal Science 75:25-32, 2002.
2001 Balog, E.M., Fruen, B.R., Shomer, N.H., Louis, C.F. :
Divergent effects of the malignant hyperthermia-susceptible Arg(615)-->Cys mutation on the Ca(2+) and Mg(2+) dependence of the RyR1. Biophys J 81:2050-8, 2001. Pubmed reference: 11566777. DOI: 10.1016/S0006-3495(01)75854-7.
Beja-Pereira, A., Bento, P., Ferrand, N., Brenig, B. :
Genetic polymorphism of the 17th exon at porcine RYR1 locus: a new variant in a local Portuguese pig breed demonstrated by SSCP analysis Journal of Animal Breeding & Genetics-Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 118:271-274, 2001.
Bina, S., Karan, S.M., Lojeski, E.W., Mongan, P.D., Muldoon, S.M. :
Prolonging viability of swine muscle biopsy specimens in malignant hyperthermia testing Anesthesia & Analgesia 93:781-786, 2001. Pubmed reference: 11524356.
Bonelli, A.M., Schifferli, C. :
Porcine stress syndrome Archivos de Medicina Veterinaria 33:125-135, 2001.
Fiedler, I., Kuhn, G., Hartung, M., Kuchenmeister, U., Nurnberg, K., Rehfeldt, C., Huber, K., Klosowska, D. :
Effects of the malignant hyperthermia syndrome (MHS) on meat quality, muscle fibre characteristics end metabolic traits of the Longissimus muscle in Pietrain pigs Archiv fur Tierzucht-Archives of Animal Breeding 44:203-217, 2001.
Kathirvel, P., Archibald, A.L. :
The halothane gene, leanness and stress susceptibility in pigs ANIMAL MODELS - DISORDERS OF EATING BEHAVIOUR AND BODY COMPOSITION :173-190, 2001.
Kerth, C.R., Carr, M.A., Ramsey, C.B., Brooks, J.C., Johnson, R.C. :
Vitamin-mineral supplementation and accelerated chilling effects on quality of pork from pigs that are monomutant or noncarriers of the halothane gene Journal of Animal Science 79:2346-2355, 2001. Pubmed reference: 11583421.
Pedersen, P.H., Oksbjerg, N., Karlsson, A.H., Busk, H., Bendixen, E., Henckel, P. :
A within litter comparison of muscle fibre characteristics and growth of halothane carrier and halothane free crossbreed pigs Livestock Production Science 73:15-24, 2001.
Piedrafita, J., Christian, L.L., Lonergan, S.M. :
Fatty acid profiles in three stress genotypes of swine and relationships with performance, carcass and meat quality traits Meat Science 57:71-77, 2001.
Swan, J.E., Parrish, F.C., Wiegand, B.R., Larsen, S.T., Baas, T.J., Berg, E.P. :
Total body electrical conductivity (TOBEC) measurement of compositional differences in hams, loins, and bellies from conjugated linoleic acid (CLA)-fed stress-genotype pigs Journal of Animal Science 79:1475-1482, 2001. Pubmed reference: 11424684.
Tor, M., Estany, J., Villalba, D., Cubilo, D., Tibau, J., Soler, J., Sanchez, A., Noguera, J.L. :
A within-breed comparison of RYR1 pig genotypes for performance, feeding behaviour, and carcass, meat and fat quality traits Journal of Animal Breeding & Genetics-Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 118:417-427, 2001.
Urban, T., Kuciel, J. :
The effect of point mutation in RYR1 gene on the semen quality traits in boars of Large White and Landrace breeds Zivocisna Vyroba 46:460-464, 2001.
Van, Oeckel, M.J., Warnants, N., Boucque, C.V., Delputte, P., Depuydt, J. :
The preference of the consumer for pork from homozygous or heterozygous halothane negative animals Meat Science 58:247-251, 2001.
Velarde, A., Gispert, M., Faucitano, L., Alonso, P., Manteca, X., Diestre, A. :
Effects of the stunning procedure and the halothane genotype on meat quality and incidence of haemorrhages in pigs Meat Science 58:313-319, 2001.
2000 Bastos, R.G., Federizzi, J., Deschamps, J.C., Cardellino, R., Dellagostin, O.A. :
Characterization of swine stress gene by DNA testing using plucked hair as a source of DNA Genetics & Molecular Biology 23:815-817, 2000.
Biedermann, G., Jatsch, C., Peschke, W., Lindner, J.P., Wittmann, W. :
Fattening and carcass performance and meat- and fat quality of Pietrain pigs of different MHS-genotype and sex. I. Fattening and carcass performance and meat quality [German] Archiv fur Tierzucht-Archives of Animal Breeding 43:151-164, 2000.
Biedermann, G., Jatsch, C., Peschke, W., Lindner, J.P., Wittmann, W. :
Fattening and carcass performance and meat- and fat quality of Pietrain pigs of different MHS-genotype and sex. II. Fatty acid pattern of the adipose tissues back fat, leaf fat and intermuscular fat and of the total- and phospholipids of the M-long. dorsi [German] Archiv fur Tierzucht-Archives of Animal Breeding 43:165-178, 2000.
Bu, H., Chen, Y., Liu, J., Li, S., Cheng, J., Li, Y. :
RYR1 genotype of the Chinese Neijiang pig Transplantation Proceedings 32:1058, 2000. Pubmed reference: 10936352.
Dietze, B., Henke, J., Eichinger, H.M., Lehmann-Horn, F., Melzer, W. :
Malignant hyperthermia mutation Arg615Cys in the porcine ryanodine receptor alters voltage dependence of Ca2+ release Journal of Physiology-London 526:507-514, 2000.
Fisher, P., Mellett, F.D., Hoffman, L.C. :
Halothane genotype and pork quality. 3. Comminuted meat products derived from the three halothane genotypes Meat Science 54:113-117, 2000.
Fisher, P., Mellett, F.D., Hoffman, L.C. :
Halothane genotype and pork quality. 1. Carcass and meat quality characteristics of three halothane genotypes Meat Science 54:97-105, 2000.
Fisher, P., Mellett, F.D., Hoffman, L.C. :
Halothane genotype and pork quality. 2. Cured meat products of three halothane genotypes Meat Science 54:107-111, 2000.
Giese, A., Deppe, A., Brenig, B., Leeb, T. :
Genomic structure of the 5 ' end of the porcine ryanodine receptor 3 gene (RYR3) DNA Sequence 11:175-179, 2000. Pubmed reference: 10902927.
Gispert, M., Faucitano, L., Oliver, M.A., Guardia, M.D., Coll, C., Siggens, K., Harvey, K., Diestre, A. :
A survey of pre-slaughter conditions, halothane gene frequency, and carcass and meat quality in five Spanish pig commercial abattoirs Meat Science 55:97-106, 2000.
Hamilton, D.N., Ellis, M., Miller, K.D., McKeith, F.K., Parrett, D.F. :
The effect of the Halothane and Rendement Napole genes on carcass and meat quality characteristics of pigs Journal of Animal Science 78:2862-2867, 2000. Pubmed reference: 11063310.
Krska, P., Lahucky, R., Kuchenmeister, U., Nurnberg, K., Kuhn, G. :
Post-mortem muscle metabolism of phosphorus compounds assessed by P-31 NMR spectroscopy in relation to vitamin E administration of pigs genotyped on malignant hyperthermia and stress susceptibility Archiv fur Tierzucht-Archives of Animal Breeding 43:229, 2000.
Kuchenmeister, U., Kuhn, G., Ender, K. :
Seasonal effects on Ca2+ transport of sarcoplasmic reticulum and on meat quality of pigs with different malignant hyperthermia status Meat Science 55:239-245, 2000.
Liou, Y.M., Jiang, M.J., Wu, M.C. :
Altered expression of cardiac myosin isozymes associated with the malignant hyperthermia genotype in swine Anesthesiology 93:1312-1319, 2000. Pubmed reference: 11046221.
Lopez, J.R., Contreras, J., Linares, N., Allen, P.D. :
Hypersensitivity of malignant hyperthermia-susceptible swine skeletal muscle to caffeine is mediated by high resting myoplasmic [Ca2+] Anesthesiology 92:1799-1806, 2000. Pubmed reference: 10839932.
Miller, K.D., Ellis, M., McKeith, F.K., Wilson, E.R. :
Influence of sire line and halothane genotype on growth performance, carcass characteristics, and meat quality in pigs Canadian Journal of Animal Science 80:319-327, 2000.
Owen, B.L., Montgomery, J.L., Ramsey, C.B., Miller, M.F. :
Preslaughter resting and hot-fat trimming effects on the incidence of pale, soft and exudative (PSE) pork and ham processing characteristics Meat Science 54:221-229, 2000.
Paulus, E.D., Henning, M., Brandt, H., Kallweit, E., Glodek, P. :
Meat production and returns of pig crosses with specific quality characteristics as compared to present standard and quality label market supplies [German] Zuchtungskunde 72:290-307, 2000.
Sigg, D.C., Iaizzo, P.A. :
Malignant hyperthermia phenotype - Hypotension induced by succinylcholine in susceptible swine Anesthesiology 92:1777-1788, 2000. Pubmed reference: 10839930.
Thaller, G., Dempfle, L., Schlecht, A., Wiedemann, S., Eichinger, H., Fries, R. :
Effects of the MHS locus on growth, carcass and meat quality traits in F-2 crosses between Mangalitza and Pietrain breeds Archiv fur Tierzucht-Archives of Animal Breeding 43:263-275, 2000.
Torley, P.J., D'Arcy, B.R., Trout, G.R. :
The effect of ionic strength, polyphosphates type, pH, cooking temperature and preblending on the functional properties of normal and pale, soft, exudative (PSE) pork Meat Science 55:451-462, 2000.
Velarde, A., Gispert, M., Faucitano, L., Manteca, X., Diestre, A. :
The effect of stunning method on the incidence of PSE meat and haemorrhages in pork carcasses Meat Science 55:309-314, 2000.
Weaver, S.A., Dixon, W.T., Schaefer, A.L. :
The effects of mutated skeletal ryanodine receptors on hypothalamic-pituitary-adrenal axis function in boars Journal of Animal Science 78:1319-1330, 2000. Pubmed reference: 10834589.
Wendt, M., Bickhardt, K., Herzog, A., Fischer, A., Martens, H., Richter, T. :
Porcine stress syndrome and PSE meat: clinical symptoms, pathogenesis, aetiology and aspects of animal welfare [Review] [German] Berliner und Munchener Tierarztliche Wochenschrift 113:173-190, 2000. Pubmed reference: 10846811.
de Vries, A.G., Faucitano, L., Sosnicki, A., Plastow, C.S. :
The use of gene technology for optimal development of pork meat quality Food Chemistry 69:397-405, 2000.
1999 Bauerova, M., Bauer, M., Vasicek, D. :
A simple and inexpensive DNA purification for malignant hyperthermia PCR detection in porcine hair roots Meat Science 51:325-327, 1999.
Bowker, B.C., Wynveen, E.J., Grant, A.L., Gerrard, D.E. :
Effects of electrical stimulation on early postmortem muscle pH and temperature declines in pigs from different genetic lines and halothane genotypes Meat Science 53:125-133, 1999.
Byrem, T.M., Booren, A.M., Hill, G.M., Chu, F.S., Strasburg, G.M. :
The effect of cyclopiazonic acid on the development of pale, soft, and exudative pork from pigs of defined malignant hyperthermia genotype Journal of Animal Science 77:166-172, 1999. Pubmed reference: 10064040.
Costa, L.N., Lo, Fiego, D.P., Dall'Olio, S., Davoli, R., Russo, V. :
Influence of loading method and stocking density during transport on meat and dry-cured ham quality in pigs with different halothane genotypes Meat Science 51:391-399, 1999.
Fiedler, I., Ender, K., Wicke, M., Maak, S., von, Lengerken, G., Meyer, W. :
Structural and functional characteristics of muscle fibres in pigs with different malignant hyperthermia susceptibility (MHS) and different meat quality Meat Science 53:9-15, 1999.
Froeba, G., Marx, T., Pazhur, J., Baur, C., Baeder, S., Calzia, E., Eichinger, H.M., Radermacher, P., Georgieff, M. :
Xenon does not trigger malignant hyperthermia in susceptible swine Anesthesiology 91:1047-1052, 1999. Pubmed reference: 10519508.
Gronek, P., Napierala, D., Nuc, K., Steppa, R., Plawski, A., Slomski, R. :
Homology of DNA sequences encompassing malignant hyperthermia mutation site in the ovine (Ovis aries) and porcine (Sus scrofa) ryr1 gene Journal of Animal Breeding & Genetics-Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 116:263-267, 1999.
Gueorguiev, I.P., Gueorguieva, T.M., Paskalev, M.D., Trifonova, K.Y. :
Erythrocytic osmotic fragility in stress-susceptible and stress-resistant pigs Revue de Medecine Veterinaire 150:39-42, 1999.
Gueorguieva, T.M., Paskalev, M.D., Gueorguiev, I.P., Angelov, G.A., Philipov, J. :
Alterations in blood gas and acid-base status in relationship to porcine stress syndrome (Malignant hyperthermia) Revue de Medecine Veterinaire 150:543-546, 1999.
Haarmann, C.S., Fink, R.H.A., Dulhunty, A.F. :
Oxidation and reduction of pig skeletal muscle ryanodine receptors Biophysical Journal 77:3010-3022, 1999. Pubmed reference: 10585923. DOI: 10.1016/S0006-3495(99)77132-8.
Harrison, G.G., Dyer, R.A., Llewellyn, R.L., James, M.F.M. :
Eltanolone (5-beta-pregnanolone) does not trigger, and attenuates halothane triggering of, malignant hyperthermia in malignant hyperthermia susceptible swine Pharmacological Research 39:103-106, 1999. Pubmed reference: 10072700. DOI: 10.1006/phrs.1998.0415.
Iaizzo, P.A., Johnson, B.A., Nagao, K., Gallagher, G.J. :
4-chloro-m-cresol triggers malignant hyperthermia in susceptible swine at doses greatly exceeding those found in drug preparations Anesthesiology 90:1723-1732, 1999. Pubmed reference: 10360872.
Jermiah, L.E., Gibson, J.P., Gibson, L.L., Ball, R.O., Aker, C., Fortin, A. :
The influence of breed, gender, and PSS (Halothane) genotype on meat quality, cooking loss, and palatability of pork Food Research International 32:59-71, 1999.
Krenkova, L., Kuciel, J., Urban, T. :
Association of the RYR1, GH, LEP and TF genes with carcass and meat quality traits in pigs Zivocisna Vyroba 44:481-486, 1999.
Kuchenmeister, U., Nurnberg, K., Fiedler, I., Kuhn, G., Nurnberg, G., Ender, K. :
Cell injury and meat duality of pig in the time period post mortem from two genotypes susceptible or resistant to malignant hyperthermia European Food Research & Technology 209:97-103, 1999.
Kumar, M.V.S., Carr, R.J., Komanduri, V., Reardon, R.F., Beebe, D.S., Iaizzo, P.A., Belani, K.G. :
Differential diagnosis of thyroid crisis and malignant hyperthermia in an anesthetized porcine model Endocrine Research 25:87-103, 1999. Pubmed reference: 10098596.
Leeb, T., Giese, A., Pfeiffer, I., Brenig, B. :
Two highly polymorphic microsatellites within the porcine ryanodine receptor 3 gene (RYR3) Animal Genetics 30:321-322, 1999. Pubmed reference: 10467714.
Monin, G., Larzul, C., Le, Roy, P., Culioli, J., Mourot, J., Rousset-Akrim, S., Talmant, A., Touraille, C., Sellier, P. :
Effects of the halothane genotype and slaughter weight on texture of pork Journal of Animal Science 77:408-415, 1999. Pubmed reference: 10100670.
Musley, S.K.V., Beebe, D.S., Komanduri, V., Iaizzo, P.A., Belani, K.G. :
Hemodynamic and metabolic manifestations of acute endotoxin infusion in pigs with and without the malignant hyperthermia mutation Anesthesiology 91:833-838, 1999. Pubmed reference: 10485795.
Reiner, G., Moser, G., Geldermann, H., Dzapo, V. :
Associations between the c-myc proto-oncogene and carcass quality traits in the pig: evidence for epistasis with the Ryr1-gene Journal of Animal Breeding & Genetics-Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 116:253-261, 1999.
Sensky, P.L., Parr, T., Lockley, A.K., Bardsley, R.G., Buttery, P.J., Wood, J.D., Warkup, C. :
Altered calpain levels in longissimus muscle from normal pigs and heterozygotes with the ryanodine receptor mutation Journal of Animal Science 77:2956-2964, 1999. Pubmed reference: 10568464.
Sobina, I., Kondratowicz, J. :
Ultrastructure of pig muscles - Morphological differences between normal, PSE and DFD meat [German] Fleischwirtschaft 79:98-100, 1999.
Wappler, F., Scholz, J., Fiege, M., Kolodzie, K., Kudlik, C., Weisshorn, R., Esch, J.S.A. :
4-chloro-m-cresol is a trigger of malignant hyperthermia in susceptible swine Anesthesiology 90:1733-1740, 1999. Pubmed reference: 10360873.
Wittmann, W., Gotz, K.U., Peschke, W., Lindner, J.P., Hauser, M. :
The influence of MHS-genotypes on fattening and carcass performance traits of purebred Pietrain pigs and PI x DL slaughter pigs at testing station [German] Archiv fur Tierzucht-Archives of Animal Breeding 42:139-147, 1999.
1998 Aalhus, J.L., Best, D.R., Murray, A.C., Jones, S.D.M. :
A comparison of the quality characteristics of pale, soft and exudative beef and pork Journal of Muscle Foods 9:267-280, 1998.
Andersen, S., Pedersen, B., Udesen, F. :
Production trait comparison of five pig sire lines with different halothane genotypes Acta Agriculturae Scandinavica Section A-Animal Science 48:237-242, 1998.
Brodbelt, D.C., Taylor, P.M. :
Delayed onset malignant hyperthermia in two pigs Veterinary Record 143:76-78, 1998. Pubmed reference: 9717223.
Cheah, K.S., Cheah, A.M., Just, A. :
Identification and characterization of pigs prone to producing RSE (reddish-pink, soft and exudative) meat in normal pigs Meat Science 48:249-255, 1998.
Desmet, S., Bloemen, H., Vandevoorde, G., Spincemaille, G., Berckmans, D. :
Meat and carcass quality in two pig lines of different stress-susceptibility genotype and their crosses Animal Science 66:441-447, 1998.
Devries, A.G., Sosnicki, A., Garnier, J.P., Plastow, G.S. :
The role of major genes and DNA technology in selection for meat quality in pigs Meat Science 49:S245-S255, 1998.
Ellis, F.R. :
Commentary - control of the malignant hyperpyrexic syndrome in mhs swine by dantrolene sodium - British Journal of Anaesthesia 1975,47-62-65 British Journal of Anaesthesia 81:625, 1998.
Godeke, K., Glodek, P., Meyer, J.N., Brandt, H. :
Effect of the MHS stress gene upon meat production and meat quality in progeny of Pietrain- and (Pietrain X Hampshire)-crossbred boars [German] Archiv fur Tierzucht-Archives of Animal Breeding 41:433-446, 1998.
Harrison, G.G. :
Control of the malignant hyperpyrexic syndrome in MHS swine by dantrolene sodium (reprinted from Br J Anaesth, vol 47, pg 62-65, 1975) British Journal of Anaesthesia 81:626-629, 1998. Pubmed reference: 9924249.
Hughes, I., Lowden, S. :
A possible genetic basis for false-positive halothane reactions in Australian pigs Journal of Animal Breeding & Genetics-Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 115:113-121, 1998.
Kauffman, R.G., van, Laack, R.L.J.M., Russell, R.L., Pospiech, E., Cornelius, C.A., Suckow, C.E., Greaser, M.L. :
Can pale, soft, exudative pork be prevented by postmortem sodium bicarbonate injection? Journal of Animal Science 76:3010-3015, 1998. Pubmed reference: 9928605.
Knyazev, S.P., Zhuchaev, K.V., Hart, V.V., Hardge, T. :
Discordance and cosegregation of swine halothane susceptibility and 1843 C-T mutation of their RYR1 locus responsible for ryanodine receptor [Russian] Genetika 34:1648-1654, 1998. Pubmed reference: 10205743.
Kohn, G., Baulain, U., Henning, M., Lahucky, R., Leibfritz, D., Kallweit, E. :
In vivo and postmortem study of muscle metabolism in pigs of different mhs genotype by means of P-31-NMR spectroscopy Archiv fur Tierzucht-Archives of Animal Breeding 41:299-310, 1998.
Kuciel, J., Krenkova, L., Urban, T. :
Polymorphisms of hae ii and msp i growth hormone genes in commercial hybrid pigs with different RYR1 genotypes Journal of Animal Breeding & Genetics-Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 115:397-402, 1998.
Kuhn, G., Hartung, M., Nurnberg, K., Fiedler, I., Falkenberg, H., Nurnberg, G., Ender, K. :
Body composition and muscle structure in genetically different pigs in dependence on mhs-status [German] Archiv fur Tierzucht-Archives of Animal Breeding 41:589-596, 1998.
Lachowicz, K., Gajowiecki, L., Dvorak, J., Czarnecki, R., Oryl, B. :
Texture and rheological properties of meat from pigs of different halothane genotypes Journal of the Science of Food & Agriculture 77:373-380, 1998.
Leeb, T., Giese, A., Al-Bayati, H., Rettenberger, G., Brenig, B. :
Assignment of the porcine ryanodine receptor 3 gene (RYR3) to chromosome 7q22-->q23. Cytogenet Cell Genet 83:244-5, 1998. Pubmed reference: 10072592. DOI: 15193.
Martens, H. :
Physiology of the muscle and the mhs-gene in pigs - a basis of discussion for breeding out the mutated ryanodin-receptor of pigs in germany [German] Archiv fur Tierzucht-Archives of Animal Breeding 41:179-192, 1998.
Murray, A.C., Johnson, C.P. :
Impact of the halothane gene on muscle quality and pre-slaughter deaths in Western Canadian pigs Canadian Journal of Animal Science 78:543-548, 1998.
Pommier, S.A., Pomar, C., Godbout, D. :
Effect of the halothane genotype and stress on animal performance, carcass composition and meat quality of crossbred pigs Canadian Journal of Animal Science 78:257-264, 1998.
Roberts, S.A., Schaefer, A.L., Murray, A.C., Thibault, L. :
Fall and winter hormone concentrations related to stress in pigs identified as normal and carrier for stress susceptibility Chronobiology International 15:275-281, 1998. Pubmed reference: 9653580.
Solomon, M.B., Vanlaack, R.L.J.M., Eastridge, J.S. :
Biophysical basis of pale, soft, exudative (pse) pork and poultry muscle - a review Journal of Muscle Foods 9:1-11, 1998.
Stalder, K.J., Christian, L.L., Rothschild, M.F., Lin, E.C. :
Effect of porcine stress syndrome genotype on the maternal performance of a composite line of stress-susceptible swine Journal of Animal Breeding & Genetics-Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 115:191-198, 1998.
Stalder, K.J., Christian, L.L., Rothschild, M.F., Lin, E.C. :
Maternal swine trait genetic parameter estimates measured on Landrace females with known porcine stress syndrome genotypes Journal of Animal Breeding & Genetics-Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 115:199-209, 1998.
Stalder, K.J., Maya, J., Christian, L.L., Moeller, S.J., Prusa, K.J. :
Effects of preslaughter management on the quality of carcasses from porcine stress syndrome heterozygous market hogs Journal of Animal Science 76:2435-2443, 1998. Pubmed reference: 9781499.
Tam, L.G., Berg, E.P., Gerrard, D.E., Sheiss, E.B., Tan, F.J., Okos, M.R., Forrest, J.C. :
Effect of halothane genotype on porcine meat quality and myoglobin autoxidation Meat Science 49:41-53, 1998.
Truett, G.E., Walker, J.A., Wilson, J.B., Redmann, S.M., Tulley, R.T., Eckardt, G.R., Plastow, G., Lefevre, M. :
ELISA detection of restriction site polymorphisms in the pig ryanodine receptor locus Mammalian Genome 9:629-632, 1998. Pubmed reference: 9680382.
Urban, T., Krenkova, L., Kuciel, J. :
Variability of pork meat quality determined by biopsy method in live pigs in various genotypes of RYR1 gene [Czech] Zivocisna Vyroba 43:209-213, 1998.
Wingertzahn, M.A., Ochs, R.S. :
Control of calcium in skeletal muscle excitation-contraction coupling - implications for malignant hyperthermia [Review] Molecular Genetics & Metabolism 65:113-120, 1998.
1997 Aalhus, J.L., Best, D.R., Costello, F., Schaefer, A.L. :
The effects of porcine somatotropin on muscle fibre morphology and meat quality of pigs of known stress susceptibility Meat Science 45:283-295, 1997.
Anon. :
Porcine stress syndrome gene sequenced Outlook on Agriculture 26:56, 1997.
Biedermann, G., Peschke, W., Wittmann, W., Brandt, C. :
The stage of reproductive, fattening and carcass performance traits of Pietrain pigs of different MHS-genotype produced in two breeding herds [German] Archiv fur Tierzucht-Archives of Animal Breeding 40:535-547, 1997.
Dugan, M.E.R., Aalhus, J.L., Murray, A.C., Larsen, I.L., Best, D.R. :
Development of pale, soft, exudative pork in halothane-negative pigs through post-mortem infusion Canadian Journal of Animal Science 77:321-323, 1997.
Dugan, M.E.R., Tong, A.K.W., Carlson, J.P., Schricker, B.R., Aalhus, J.L., Schaefer, A.L., Sather, A.P., Murray, A.C., Jones, S.D.M. :
The effects of porcine somatotropin, gender and porcine stress syndrome on growth, carcass composition and pork quality Canadian Journal of Animal Science 77:233-240, 1997.
Fisher, P., Mellett, F.D. :
Halothane genotype and pork production - 1 - growth, carcass and meat quality characteristics South African Journal of Animal Science-Suid-Afrikaanse Tydskrif vir Veekunde 27:22-26, 1997.
Fisher, P., Mellett, F.D. :
Halothane genotype and pork production - 2 - processed pork products South African Journal of Animal Science-Suid-Afrikaanse Tydskrif vir Veekunde 27:27-30, 1997.
Hartmann, S., Otten, W., Kratzmair, M., Seewald, M.J., Iaizzo, P.A., Eichinger, H.M. :
Influences of breed, sex, and susceptibility to malignant hyperthermia on lipid composition of skeletal muscle and adipose tissue in swine American Journal of Veterinary Research 58:738-743, 1997. Pubmed reference: 9215450.
Kallweit, E., Baulain, U., Henning, M., Kohn, G. :
In-vivo investigation of stress susceptibility in pig by means of magnetic resonance-spectroscopy [German] Deutsche Tierarztliche Wochenschrift 104:380-383, 1997. Pubmed reference: 9410728.
Kannan, M.S., Prakash, Y.S., Brenner, T., Mickelson, J.R., Sieck, G.C. :
Role of ryanodine receptor channels in Ca2+ oscillations of porcine tracheal smooth muscle. Am J Physiol 272:L659-64, 1997. Pubmed reference: 9142939.
Kozakribbens, G., Bendahan, D., Rodet, L., Confortgouny, S., Miri, A., Talmant, A., Monin, G., Cozzone, P.J. :
Metabolic events with spontaneous malignant hyperthermia crisis in an anaesthetized pig Canadian Journal of Anaesthesia 44:757-764, 1997. Pubmed reference: 9232308. DOI: 10.1007/BF03013392.
Lahucky, R., Christian, L.L., Kovac, L., Stalder, K.J., Bauerova, M. :
Meat quality assessed ante- and post mortem by different ryanodine receptor gene status of pigs Meat Science 47:277-285, 1997.
Lahucky, R., Marinova, P., Astruc, T., Vignon, X., Monin, G. :
Effect of malignant hyperthermia and slaughter on myofilament spacing and extracellular space in pig muscle Archiv fur Tierzucht-Archives of Animal Breeding 40:357-363, 1997.
Larzul, C., Leroy, P., Gueblez, R., Talmant, A., Gogue, J., Sellier, P., Monin, G. :
Effect of halothane genotype (NN, Nn, nn) on growth, carcass and meat quality traits of pigs slaughtered at 95 kg or 125 kg live weight Journal of Animal Breeding & Genetics-Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 114:309-320, 1997.
Lockley, A.K., Bruce, J.S., Franklin, S.J., Bardsley, R.G. :
Simultaneous detection of a sex-specific sequence and the RYR1 point mutation in porcine genomic dna Meat Science 45:485-490, 1997.
Looft, C., Kalm, E. :
Breeding for meat quality by means of gene diagnosis [German] Fleischwirtschaft 77:545-547, 1997.
Mccaw, J., Ellis, M., Brewer, M.S., Mckeith, F.K. :
Incubation temperature effects on physical characteristics of normal, dark, firm and dry, and halothane-carrier pork longissimus Journal of Animal Science 75:1547-1552, 1997. Pubmed reference: 9250516.
Mitchell, A.D., Scholz, A. :
Dual-energy x-ray absorptiometry (dxa) analysis of growth and composition of pigs of different ryanodine receptor genotypes Archiv fur Tierzucht-Archives of Animal Breeding 40:47-56, 1997.
Otten, W., Iaizzo, P.A., Eichinger, H.M. :
Effects of a high N-3 fatty acid diet on membrane lipid composition of heart and skeletal muscle in normal swine and in swine with the genetic mutation for malignant hyperthermia Journal of Lipid Research 38:2023-2034, 1997. Pubmed reference: 9374125.
Owen, V.J., Taske, N.L., Lamb, G.D. :
Reduced MG2+ inhibition of CA2+ release in muscle fibers of pigs susceptible to malignant hyperthermia American Journal of Physiology - Cell Physiology 41:C 203-C 211, 1997.
Palnitkar, S.S., Mickelson, J.R., Louis, C.F., Parness, J. :
Pharmacological distinction between dantrolene and ryanodine binding sites - evidence from normal and malignant hyperthermia-susceptible porcine skeletal muscle Biochemical Journal 326:847-852, 1997. Pubmed reference: 9307036.
Roberge, C., Pommier, S.A., Houde, A. :
Rapid DNA purification for hal gene PCR diagnosis in porcine tissues and extension to other meat species Meat Science 45:17-22, 1997.
Sarac, M., Gagrcin, M., Jovanovic, S. :
Detection of mutation T-C 1843 in the RYR1 gene, polymorphic protein and enzyme systems associated with malignant hyperthermia in Yugoslav autochtonal pig breeds Acta Veterinaria-Beograd 47:195-202, 1997.
Sorheim, O., Erlandsen, T., Nissen, H., Lea, P., Hoyem, T. :
Effects of modified atmosphere storage on colour and microbiological shelf life of normal and pale, soft and exudative pork Meat Science 47:147-155, 1997.
Stalder, K.J., Christian, L.L., Rothschild, M.F., Lin, E.C. :
Maternal performance differences between porcine stress syndrome normal and -carrier Landrace females Journal of Animal Science 75:3114-3118, 1997. Pubmed reference: 9419983.
Sutko, J.L., Airey, J.A., Welch, W., Ruest, L. :
The pharmacology of ryanodine and related compounds [Review] Pharmacological Reviews 49:53-98, 1997. Pubmed reference: 9085309.
Sutton, D.S., Ellis, M., Lan, Y., Mckeith, F.K., Wilson, E.R. :
Influence of slaughter weight and stress gene genotype on the water-holding capacity and protein gel characteristics of three porcine muscles Meat Science 46:173-180, 1997.
Thiemig, F., Buhr, H., Oelker, P. :
Problems connected with the prediction of pse pork [German] Fleischwirtschaft 77:229-234, 1997.
Thiemig, F., Oelker, P., Buhr, H. :
Influence of exsanguination on PSE characteristics in pigs - possibilities to eliminate reflectory and motorical cramps during exsanguination [German] Fleischwirtschaft 77:1030-1033, 1997.
Vonlengerken, G., Wicke, M., Maak, S. :
Stress susceptibility and meat quality - situation and prospects in animal breeding and research [German] Archiv fur Tierzucht-Archives of Animal Breeding 40:163-171, 1997.
Wagenknecht, T., Radermacher, M. :
Ryanodine receptors - structure and macromolecular interactions Current Opinion in Structural Biology 7:258-265, 1997. Pubmed reference: 9094329.
Zucchi, R., Roncatestoni, S. :
The sarcoplasmic reticulum CA2+ channel/ryanodine receptor - modulation by endogenous effectors, drugs and disease states [Review] Pharmacological Reviews 49:1-51, 1997. Pubmed reference: 9085308.
1996 Bjurstrom, S., Carlsten, J., Jonsson, L. :
Absence of skeletal muscle lesions after experimental restraint stress induced by pancuronium in normal and stress-susceptible pigs Zentralblatt Fur Veterinarmedizin - Reihe A 43:129-138, 1996. Pubmed reference: 8693835.
Bogner, P., Berenyi, E., Miseta, A., Horn, P., Kellermayer, M., Wheatley, D.N., Jolesz, F.A. :
Nuclear magnetic resonance relaxation parameters of muscle in malignant hyperthermia-susceptible swine Academic Radiology 3:26-30, 1996. Pubmed reference: 8796636.
Borton, C.L. :
MH in piglets Anaesthesia & Intensive Care 24:725, 1996.
Brenig, B., Leeb, T. :
Identification of a G/C transversion polymorphism in intron 38 of the porcine skeletal muscle ryanodine receptor gene Animal Genetics 27:128, 1996. Pubmed reference: 8856914.
Brenig, B., Schmoelzl, S., Leeb, T., Wen, G., Reinhart, B., Baumgartner, B., Krempler, A. :
Structure and expression of the porcine skeletal muscle ryanodine receptor gene [German] Deutsche Tierarztliche Wochenschrift 103:394-399, 1996. Pubmed reference: 9035969.
Denborough, M. :
MH in piglets - reply Anaesthesia & Intensive Care 24:725, 1996.
Denborough, M., Hopkinson, K.C., Obrien, R.O., Foster, P.S. :
Overheating alone can trigger malignant hyperthermia in piglets Anaesthesia & Intensive Care 24:348-354, 1996.
Desmet, S.M., Pauwels, H., Debie, S., Demeyer, D.I., Callewier, J., Eeckhout, W. :
Effect of halothane genotype, breed, feed withdrawal, and lairage on pork quality of Belgian slaughter pigs Journal of Animal Science 74:1854-1863, 1996. Pubmed reference: 8856440.
Dovc, P., Salehar, A., Kovac, M., Kastelic, M. :
Frequency of the RYR1 n allele and its influence on fattening traits Archiv fur Tierzucht-Archives of Animal Breeding 39:441-446, 1996.
Gallant, E.M., Balog, E.M., Beam, K.G. :
Slow calcium current is not reduced in malignant hyperthermic porcine myotubes Muscle & Nerve 19:450-455, 1996. Pubmed reference: 8622723. DOI: 10.1002/(SICI)1097-4598(199604)19:4<450::AID-MUS4>3.0.CO;2-B.
Gallant, E.M., Jordan, R.C. :
Porcine malignant hyperthermia - genotype and contractile threshold of immature muscles Muscle & Nerve 19:68-73, 1996. Pubmed reference: 8538672. DOI: 10.1002/(SICI)1097-4598(199601)19:1<68::AID-MUS9>3.0.CO;2-6.
Garciamacias, J.A., Gispert, M., Oliver, M.A., Diestre, A., Alonso, P., Munozluna, A., Siggens, K., Cuthbertheavens, D. :
The effects of cross, slaughter weight and halothane genotype on leanness and meat and fat quality in pig carcasses Animal Science 63:487-496, 1996.
Geers, R., Decanniere, C., Rosier, A., Ville, H., Vanhecke, P., Vandesande, F., Jourquin, J. :
Variability of energy metabolism and nuclear T-3-RECEPTORS within the skeletal muscle tissue of pigs different with respect to the halothane gene Journal of Animal Science 74:717-722, 1996. Pubmed reference: 8727990.
Hammel, M., Muller, E., Fewson, D. :
Selection experiment with german landrace pigs to investigate the genetic antagonisms between meat content, meat quality and stress resistance [German] Zuchtungskunde 68:384-397, 1996.
Iaizzo, P.A., Kehler, C.H., Carr, R.J., Sessler, D.I., Belani, K.G. :
Prior hypothermia attenuates malignant hyperthermia in susceptible swine Anesthesia & Analgesia 82:803-809, 1996. Pubmed reference: 8615501.
Iaizzo, P.A., Kehler, C.H., Zink, R.S., Belani, K.G., Sessler, D.I. :
Thermal response in acute porcine malignant hyperthermia Anesthesia & Analgesia 82:782-789, 1996. Pubmed reference: 8615498.
Iaizzo, P.A., Sessler, D.I. :
Skeletal muscle is responsible for heat production in porcine malignant hyperthermia - response Anesthesia & Analgesia 83:1134, 1996. Pubmed reference: 8895311.
Karan, S.M., Lojeski, E.W. :
Skeletal muscle is responsible for heat production in porcine malignant hyperthermia Anesthesia & Analgesia 83:1133-1134, 1996. Pubmed reference: 8895310.
Karan, S.M., Lojeski, E.W., Haynes, D.H., Bina, S., Wesche, D.L., Boedeker, B.H., Muldoon, S.M. :
Intravenous lecithin-coated microcrystals of dantrolene are effective in the treatment of malignant hyperthermia - an investigation in rats, dogs, and swine Anesthesia & Analgesia 82:796-802, 1996. Pubmed reference: 8615500.
Knyazev, S.P., Hardge, T., Zhuchaev, K.V. :
Molecular genetic screening of siberian swine populations - local breeds are free of the genetic load of malignant hyperthermia [Russian] Genetika 32:1423-1425, 1996. Pubmed reference: 9091417.
Kuciel, J., Lahucky, R. :
Genes with major effect on pork quality [Czech] Zivocisna Vyroba 41:475-480, 1996.
Lambert, A.J., Houde, A., Drolet, R., Dallaire, S. :
Determination of halothane gene mutation associated with malignant hyperthermia in sows dead of cardiac failure Journal of Veterinary Diagnostic Investigation 8:513-515, 1996. Pubmed reference: 8953548.
Leach, L.M., Ellis, M., Sutton, D.S., Mckeith, F.K., Wilson, E.R. :
The growth performance, carcass characteristics, and meat quality of halothane carrier and negative pigs Journal of Animal Science 74:934-943, 1996. Pubmed reference: 8726723.
Lockley, A.K., Bruce, J.S., Franklin, S.J., Bardsley, R.G. :
Use of mutagenically separated PCR for the detection of the mutation associated with porcine stress syndrome Meat Science 43:93-97, 1996.
Maccani, R.M., Wedel, D.J., Hofer, R.E. :
Norepinephrine does not potentiate porcine malignant hyperthermia Anesthesia & Analgesia 82:790-795, 1996. Pubmed reference: 8615499.
Mickelson, J.R., Louis, C.F. :
Malignant hyperthermia - excitation-contraction coupling, CA2+ release channel, and cell CA2+ regulation defects [Review] Physiological Reviews 76:537-592, 1996. Pubmed reference: 8618963.
Nakajima, E., Matsumoto, T., Yamada, R., Kawakami, K., Takeda, K., Ohnishi, A., Komatsu, M. :
Technical note - use of a PCR-single strand conformation polymorphism (PCR-SSCP) for detection of a point mutation in the swine ryanodine receptor (RYR1) gene Journal of Animal Science 74:2904-2906, 1996. Pubmed reference: 8994903.
Neubert, E., Gurtler, H., Vallentin, G. :
Effect of acute stress on plasma levels of catecholamines, cortisol and metabolites in stress-susceptible growing pigs [German] Berliner und Munchener Tierarztliche Wochenschrift 109:381-384, 1996. Pubmed reference: 8999769.
Otten, W., Eichinger, H.M. :
Carbohydrate and lipid metabolism at rest and under physical and metabolic load in normal pigs and those with the genetic mutation for malignant hyperthermia Animal Science 62:581-590, 1996.
Rasmussen, U.F., Rasmussen, H.N., Andersen, A.J., Jorgensen, P.F., Quistorff, B. :
Characterization of mitochondria from pig muscle - higher activity of exo-nadh oxidase in animals suffering from malignant hyperthermia Biochemical Journal 315:659-663, 1996. Pubmed reference: 8615844.
Richter, A., Scholz, J., Loscher, W., Tonner, P.H., Wappler, F. :
Effects of the 5-HT2 receptor antagonist ritanserin on halothane-induced increase of inositol phosphates in porcine malignant hyperthermia Naunyn-Schmiedebergs Archives of Pharmacology 354:593-597, 1996.
Roberts, S.A., Thibault, L., Murray, A.C., Schaefer, A.L. :
The effect of dietary protein source on biochemical indices of stress in stress-susceptible pigs Canadian Journal of Animal Science 76:401-408, 1996.
Sarac, M., Jovanovic, S., Gagrcin, M. :
PCR genotyping of the ryanodine receptor gene RYR1 in Yugoslav meat swine Acta Veterinaria 46:185-191, 1996.
Schwagele, F., Haschke, C., Krauss, G., Honikel, K.O. :
Comparative studies of pyruvate kinase from pse and normal pig muscles Zeitschrift fur Lebensmittel-Untersuchung und -Forschung 203:14-20, 1996. Pubmed reference: 8765986.
Sutko, J.L., Airey, J.A. :
Ryanodine receptor CA2+ release channels - does diversity in form equal diversity in function [Review] Physiological Reviews 76:1027-1071, 1996. Pubmed reference: 8874493.
Wen, G., Leeb, T., Reinhart, B., Schmoelzl, S., Brenig, B. :
The porcine skeletal muscle ryanodine receptor gene structure coding region 1 to 10,614 harbouring 71 exons Animal Genetics 27:297-304, 1996. Pubmed reference: 8930069.
Zinovieva, N., Vasicek, D., Aigner, B., Muller, M., Brem, G. :
Short communication - single tube allele specific (stas) pcr for direct determination of the mutation in the porcine ryanodine receptor gene associated with malignant hyperthermia Animal Biotechnology 7:173-177, 1996.
1995 Backstrom, L., Kauffman, R. :
The porcine stress syndrome - a review of genetics, environmental factors, and animal well-being implications Agri-Practice 16:24-30, 1995.
Bauerova, M., Vasicek, D., Uhrin, P., Chrenek, P., Kminiak, M., Bulla, J. :
Detection of malignant hyperthermia in pigs by PCR-RFLP analysis using plucked hair as a source of DNA Zivocisna Vyroba 40:145-147, 1995.
Belonje, P.C., Wilson, G.R., Berman, P.A., Human, L. :
Sudden death in laboratory rats induced by acute respiratory alkalosis: Biochemical similarities to malignant hyperthermia in pigs South African Journal of Science 91:18-20, 1995.
Bjurstrom, S., Carlsten, J., Jonsson, L. :
The reduction of skeletal muscle lesions after experimental stress in stress-susceptible pigs protected with dantrolene Journal of Veterinary Medicine - Series A 42:659-667, 1995. Pubmed reference: 8822190.
Bjurstrom, S., Carlsten, J., Thorentolling, K., Jonsson, L. :
Distribution and morphology of skeletal muscle lesions after experimental restraint stress in normal and stress-susceptible pigs Journal of Veterinary Medicine - Series A 42:575-587, 1995. Pubmed reference: 8822194.
Casteels, M., Vanoeckel, M.J., Boschaerts, L., Spincemaille, G., Boucque, C.V. :
The relationship between carcass, meat and eating quality of three pig genotypes Meat Science 40:253-269, 1995.
Cheah, K.S., Cheah, A.M., Krausgrill, D.I. :
Variations in Meat Quality in Live Halothane Heterozygotes Identified by Biopsy Samples of M Longissimus Dorsi Meat Science 39:293-300, 1995.
Desmet, S., Pauwels, H., Vervaeke, I., Demeyer, D., Debie, S., Eeckhout, W., Casteels, M. :
Meat and carcass quality of heavy muscled Belgian slaughter pigs as influenced by halothane sensitivity and breed Animal Production 61:109-114, 1995.
Dvorak, J., Hradil, R., Nebola, M. :
Frequency of genotypes and alleles of halothane locus in pigs of the large white breed in the Czech Republic Zivocisna Vyroba 40:103-107, 1995.
Elhayek, R., Yano, M., Antoniu, B., Mickelson, J.R., Louis, C.F., Ikemoto, N. :
Altered E-C coupling in triads isolated from malignant hyperthermia-susceptible porcine muscle American Journal of Physiology - Cell Physiology 37:C1381-C1386, 1995.
Gregor, G., Hardge, T. :
The influence of gene variants at the ryanodine-receptor on sperm quality of AI boars [German] Archiv fur Tierzucht-Archives of Animal Breeding 38:527-538, 1995.
Hanset, R., Dasnois, C., Scalais, S., Michaux, C., Grobet, L. :
Introgression into the Pietrain genome of the normal allele at the locus for halothane sensitivity Genetics Selection Evolution 27:77-88, 1995.
Hanset, R., Dasnois, C., Scalais, S., Michaux, C., Grobet, L. :
Genotypes at the locus for halothane sensitivity and performance in a Pietrain x large white F2 Genetics Selection Evolution 27:63-76, 1995.
Hanset, R., Scalais, S., Grobet, L. :
From the classical type Pietrain to halothane-resistant Pietrain, or Pietrain Rehal Annales de Medecine Veterinaire 139:23-35, 1995.
Klont, R.E., Lambooy, E. :
Influence of preslaughter muscle temperature an muscle metabolism and meat quality in anesthetized pigs of different halothane genotypes Journal of Animal Science 73:96-107, 1995. Pubmed reference: 7601760.
Klont, R.E., Lambooy, E. :
Effects of preslaughter muscle exercise on muscle metabolism and meat quality studied in anesthetized pigs of different halothane genotypes Journal of Animal Science 73:108-117, 1995. Pubmed reference: 7601723.
Kocwinpodsiadla, M., Przybylski, W., Kuryl, J., Talmant, A., Monin, G. :
Muscle Glycogen Level and Meat Quality in Pigs of Different Halothane Genotypes Meat Science 40:121-125, 1995.
Kuciel, J., Dvorak, J., Nespor, F., Nebola, M., Hartl, J. :
PH(1) values of meat of hybrid pigs with heterozygous genotypes of hal locus [Czech] Zivocisna Vyroba 40:417-420, 1995.
Lahucky, R., Madajova, V., Mharapara, O., Marak, J., Kaniansky, D., Poltarsky, J., Kovac, L. :
A Comparison of Some Metabolites in Skeletal Muscle of Different Halothane Sensitivity with Meat Quality Traits of Pigs Using a Capillary Isotachophoresis Technique Meat Science 39:403-414, 1995.
Lahucky, R., Uhrin, V. :
Structural and functional characteristics of the skeletal muscle related to the meat quality of pigs [Czech] Zivocisna Vyroba 40:421-428, 1995.
Leeb, T., Rettenberger, G., Hameister, H., Brem, G., Brenig, B. :
Construction of a porcine YAC library and mapping of the cardiac muscle ryanodine receptor gene to chromosome 14q22-q23 Mammalian Genome 6:37-41, 1995. Pubmed reference: 7719024.
Lokuta, A.J., Rogers, T.B., Lederer, W.J., Valdivia, H.H. :
Modulation of cardiac ryanodine receptors of swine and rabbit by a phosphorylation-dephosphorylation mechanism Journal of Physiology 487:609-622, 1995. Pubmed reference: 8544125.
Lundstrom, K., Karlsson, A., Hakansson, J., Hansson, I., Johansson, M., Andersson, L., Andersson, K. :
Production, carcass and meat quality traits of F-2-CROSSES between european wild pigs and domestic pigs including halothane gene carriers Animal Production 61:325-331, 1995.
Mcphee, C.P., Trout, G.R. :
The effects of selection for lean growth and the halothane allele on carcass and meat quality of pigs transported long and short distances to slaughter Livestock Production Science 42:55-62, 1995.
Moesgaard, B., Quistorff, B., Christensen, V.G., Therkelsen, I., Jorgensen, P.F. :
Differences of Post-Mortem ATP Turnover in Skeletal Muscle of Normal and Heterozygote Malignant-Hyperthermia Pigs - Comparison of P-31-NMR and Analytical Biochemical Measurements Meat Science 39:43-57, 1995.
Nelson, T.E., Lin, M. :
Abnormal function of porcine malignant hyperthermia calcium release channel in the absence and presence of halothane Cellular Physiology and Biochemistry 5:10-22, 1995.
Nurnberg, K., Kuhn, G., Nurnberg, G., Rehfeldt, C., Ender, K. :
Effect of porcine somatotropin (pST) on body composition, meat quality and characteristics of backfat in genetically different pigs Fett Wissenschaft Technologie - Fat Science Technology 97:153-158, 1995.
O'Brien, P.J. :
The causative mutation for porcine stress syndrome Compendium on Continuing Education for the Practicing Veterinarian 17:257, 1995.
Petrovic, L., Okanovic, D., Rede, R. :
Film-Packed Cooked Ham Made from PSE Meat - Properties of Finished Products Fleischwirtschaft 75:712, 1995.
Petrovic, L., Okanovic, D., Rede, R. :
Film-Packed Cooked Hams from PSE Meat - The Properties of Normal and PSE Muscles Fleischwirtschaft 75:480-481, 1995.
Rehfeldt, C., Ender, K. :
Somatotropin action on skeletal muscle and backfat cellularity in pigs of different breed and halothane sensitivity Archiv Fur Tierzucht - Archives of Animal Breeding 38:405-415, 1995.
Rempel, W.E., Lu, M.Y., Mickelson, J.R., Louis, C.F. :
The effect of skeletal muscle ryanodine receptor genotype on pig performance and carcass quality traits Animal Science 60:249-257, 1995.
Roewer, N., Dziadzka, A., Greim, C.A., Kraas, E., Esch, J.S.A. :
Cardiovascular and metabolic responses to anesthetic-induced malignant hyperthermia in swine Anesthesiology 83:141-159, 1995. Pubmed reference: 7604993.
Roewer, N., Greim, C., Rumberger, E., Esch, J.S.A. :
Abnormal action potential responses to halothane in heart muscle isolated from malignant hyperthermia-susceptible pigs Anesthesiology 82:947-953, 1995. Pubmed reference: 7717567.
Scholz, A., Mitchell, A.D., Wang, P.C., Song, H.F., Yan, Z.J. :
Muscle metabolism and body composition of pigs with different ryanodine receptor genotypes studied by means of P-31 nuclear magnetic resonance spectroscopy and H-1 magnetic resonance imaging Archiv fur Tierzucht-Archives of Animal Breeding 38:539-552, 1995.
Shaw, F.D., Trout, G.R., Mcphee, C.P. :
Plasma and Muscle Cortisol Measurements as Indicators of Meat Quality and Stress in Pigs Meat Science 39:237-246, 1995.
Shomer, N.H., Mickelson, J.R., Louis, C.F. :
CA2+ release channels of pigs heterozygous for malignant hyperthermia Muscle & Nerve 18:1167-1176, 1995. Pubmed reference: 7659111. DOI: 10.1002/mus.880181013.
Tonner, P.H., Scholz, J., Richter, A., Loscher, W., Steinfath, M., Wappler, F., Wlaz, P., Hadji, B., Roewer, N., Esch, J.S.A. :
Alterations of inositol polyphosphates in skeletal muscle during porcine malignant hyperthermia British Journal of Anaesthesia 75:467-471, 1995. Pubmed reference: 7488490.
Vanderwal, P.G., Devries, A.G., Eikelenboom, G. :
Predictive value of slaughterhouse measurements of ultimate pork quality in seven halothane negative Yorkshire populations Meat Science 40:183-191, 1995.
Wahle, K.W.J., Morrice, P.C., Arthur, J.R., Duthie, G.G. :
Decreased phospholipid polyunsaturated fatty acid content and superoxide dismutase activity in cardiac muscle of malignant hyperthermia-susceptible swine Comparative Biochemistry & Physiology - B: Comparative Biochemistry 112:283-286, 1995.
1994 Berenyi, E., Bogner, P., Miseta, A., Kover, G., Horn, P., Wheatley, D.N. :
Pre-Slaughter Characteristics of Proton NMR Relaxation Parameters in Malignant Hyperthermia Susceptible Pigs Sciences Des Aliments 14:459-467, 1994.
Boles, J.A., Patience, J.F., Schaefer, A.L., Aalhus, J.L. :
Effect of Oral Loading of Acid or Base on the Incidence of Pale Soft Exudative Pork (PSE) in Stress-Susceptible Pigs Meat Science 37:181-194, 1994.
Carlsten, J., Bjurstrom, S., Haggendal, J., Jonsson, L. :
Reduction of heart lesions after experimental restraint stress: A study in stress-susceptible pigs Journal of Veterinary Medicine Series A - Zentralblatt Fur Veterinarmedizin Reihe A - Physiology Pathology Clinical Medicine 41:722-730, 1994.
Chang, H.L., Wu, M.C., Wu, S.C., Kao, Z.C., Yen, N.T., Tsay, J.S., Liu, C.T., Lai, Y.Y. :
The incidence of reaction of halothane test in taiwan landrace, yorkshire, and duroc piglets [Chinese] Journal of the Agricultural Association of China :116-124, 1994.
Cheah, A.M., Cheah, K.S., Lahucky, R., Kovac, L., Kramer, H.L., Mcphee, C.P. :
Identification of Halothane Genotypes by Calcium Accumulation and Their Meat Quality Using Live Pigs Meat Science 38:375-384, 1994.
Coronado, R., Morrissette, J., Sukhareva, M., Vaughan, D.M. :
Structure and function of ryanodine receptors American Journal of Physiology 266:C1485-C1504, 1994. Pubmed reference: 8023884.
Dvorzak, J., Nebola, M. :
Analysis of Genotype Distribution in HAL Locus in Pigs of Landrace Breed Zivocisna Vyroba 39:781-788, 1994.
Essen-Gustavsson, B., Karlsson, A., Lundstrom, K., Enfalt, A.C. :
Intramuscular Fat and Muscle Fibre Lipid Contents in Halothane-Gene-Free Pigs Fed High or Low Protein Diets and Its Relations to Meat Quality Meat Science 38:269-277, 1994.
Fisher, P., Purves, L., Rubenstein, R., Mellett, F.D. :
The Effect of the Malignant Hyperthermia Gene on Carcass Characteristics of Commercial Crossbred Pigs in the Western Cape South African Journal of Animal Science - Suid - Afrikaanse Tydskrif Vir Veekunde 24:111-112, 1994.
Fuentes, O., Valdivia, C., Vaughan, D., Coronado, R., Valdivia, H.H. :
Calcium-Dependent Block of Ryanodine Receptor Channel of Swine Skeletal Muscle by Direct Binding of Calmodulin Cell Calcium 15:305-316, 1994. Pubmed reference: 8055547.
Geers, R., Bleus, E., Vanschie, T., Ville, H., Nackaerts, G., Decuypere, E., Jourquin, J., Gerard, H., Janssens, S. :
Transport of pigs different with respect to the halothane gene: Stress assessment Journal of Animal Science 72:2552-2558, 1994. Pubmed reference: 7883611.
Gurtler, H., Neubert, E. :
Effects of Anaesthesia, of Alpha- and Beta-Adrenergic Blockers in Conscious and of Epinephrine in Anaesthetized Halothane-Sensitive Pigs on Haematological and Metabolic Parameters in Blood During Halothane Exposition Berliner und Munchener Tierarztliche Wochenschrift 107:1-7, 1994. Pubmed reference: 8129701.
Hilbert, F., Fleckna, G., Seiwald, G., Mayr, B. :
PCR-Analysis of the Ryanodine Receptor Gene for MHS- Genotyping in Austrian Pig Breeds .3. PSE-Diagnosis of Cross Breed Slaughter Pigs Wiener Tierarztliche Monatsschrift 81:129-134, 1994.
Iaizzo, P.A., Wedel, D.J. :
Response to succinylcholine in porcine malignant hyperthermia Anesthesia and Analgesia 79:143-151, 1994. Pubmed reference: 8010426.
Janzen, E.G., Gareau, P.J., Stewart, W.A., Towner, R.A. :
The Use of Invivo Magnetic Resonance Imaging and Spectroscopy to Study Porcine Stress Syndrome in Young, Halothane- Susceptible Pigs - Preliminary Results Canadian Journal of Animal Science 74:37-43, 1994.
Karlsson, A., Essen-Gustavsson, B., Lundstrom, K. :
Muscle Glycogen Depletion Pattern in Halothane-Gene-Free Pigs at Slaughter and Its Relation to Meat Quality Meat Science 38:91-101, 1994.
Loscher, W., Gerdes, C., Richter, A. :
Lack of prophylactic or therapeutic efficacy of 5-HT(2A) receptor antagonists in halothane-induced porcine malignant hyperthermia Naunyn - Schmiedebergs Archives of Pharmacology 350:365-374, 1994.
Louis, C.F., Roghair, T., Mickelson, J.R. :
Volatile Anesthetics Inhibit Dihydropyridine Binding to Malignant Hyperthermia-Susceptible and Normal Pig Skeletal Muscle Membranes Anesthesiology 80:618-624, 1994. Pubmed reference: 8141457.
Mcphee, C.P., Daniels, L.J., Kramer, H.L., Macbeth, G.M., Noble, J.W. :
The Effects of Selection for Lean Growth and the Halothane Allele on Growth Performance and Mortality of Pigs in a Tropical Environment Livestock Production Science 38:117-123, 1994.
Mickelson, J.R., Ervasti, J.M., Litterer, L.A., Campbell, K.P., Louis, C.F. :
Skeletal muscle junctional membrane protein content in pigs with different ryanodine receptor genotypes American Journal of Physiology 267:C282-C292, 1994. Pubmed reference: 8048487.
Murray, A.C., Jones, S.D.M. :
The effect of mixing, feed restriction and genotype with respect to stress susceptibility on pork carcass and meat quality Canadian Journal of Animal Science 74:587-594, 1994.
Nebola, M., Dvorak, J., Kuciel, J. :
Determination of Pig Sensitivity to Stress DNA-Test Zivocisna Vyroba 39:789-794, 1994.
Nurnberg, K., Kuhn, G., Ender, K., Nurnberg, G. :
Effect of Porcine Somatotropin (pST) on Carcass Quality and Adipose Tissue Composition in Genetically Different Pigs Archiv Fur Tierzucht - Archives of Animal Breeding 37:265-278, 1994.
Ryan, J.F., Lopez, J.R., Sanchez, V.B., Sreter, F.A., Allen, P.D. :
Myoplasmic calcium changes precede metabolic and clinical signs of porcine malignant hyperthermia Anesthesia and Analgesia 79:1007-1011, 1994. Pubmed reference: 7978379.
Schellander, K., Peli, J., Kneissl, F., Schmoll, F., Mayr, B. :
Variation of the Growth Hormone Gene in Ryr-1 Genotyped Austrian Pig Breeds Journal of Animal Breeding and Genetics - Zeitschrift Fur Tierzuchtung und Zuchtungsbiologie 111:162-166, 1994.
Scholz, A., Hardge, T. :
Effect of MHS-Genotype and Breed on Fattening Performance, Carcass Value and Meat Quality Archiv Fur Tierzucht - Archives of Animal Breeding 37:245-256, 1994.
Schwagele, F., Lopez, P., Haschke, C., Honikel, K.O. :
Rapid pH Drop in PSE-Muscles - Enzymological Investigations into the Causes Fleischwirtschaft 74:95, 1994.
Shomer, N.H., Mickelson, J.R., Louis, C.F. :
Ion selectivity of porcine skeletal muscle Ca2+ release channels is unaffected by the Arg(615) to Cys(615) mutation Biophysical Journal 67:641-646, 1994. Pubmed reference: 7948678. DOI: 10.1016/S0006-3495(94)80524-7.
Solti, L., Bosze, Z. :
DNA-test for detection of porcine stress-susceptibility Reproduction in Domestic Animals 29:379-381, 1994.
Szilagyi, M., Sankari, S., Lindberg, P., Wittmann, M. :
Selenium Status and Serum Biochemical Parameters in Halothane Positive and Negative Pigs Archiv Fur Tierzucht - Archives of Animal Breeding 37:279-286, 1994.
Vogeli, P., Bolt, R., Fries, R., Stranzinger, G. :
Co-segregation of the malignant hyperthermia and the Arg(615)- Cys(615) mutation in the skeletal muscle calcium release channel protein in five European Landrace and Pietrain pig breeds Animal Genetics 25:59-66, 1994. Pubmed reference: 7943985.
Wittmann, W., Linnert, B., Pfeiffer, H., Peschke, W. :
Influence of Gene-Markers on Breeding, Fattening and Carcass Performance Traits of a Homozygous Stress-Resistant German- Landrace Sow Herd Archiv Fur Tierzucht - Archives of Animal Breeding 37:411-425, 1994.
1993 Adeola, O., Ball, R.O., House, J.D., Obrien, P.J. :
Regional Brain Neurotransmitter Concentrations in Stress- Susceptible Pigs Journal of Animal Science 71:968-974, 1993. Pubmed reference: 8097511.
Allen, G.C. :
VIth International Workshop on Malignant Hyperthermia (MH) Canadian Journal of Anaesthesia - Journal Canadien D Anesthesie 40:284-285, 1993.
Boles, J.A., Shand, P.J., Patience, J.F., Mccurdy, A.R., Schaefer, A.L. :
Acid Base Status of Stress Susceptible Pigs Affects Sensory Quality of Loin Roasts Journal of Food Science 58:1254-1257, 1993.
Bolt, R., Vogeli, P., Fries, R. :
A Polymorphic Microsatellite at the RYR1 Locus in Swine Animal Genetics 24:72, 1993. Pubmed reference: 8388671.
Brem, G., Brenig, B. :
The Use of Molecular Gene Diagnostics of Malignant Hyperthermic Syndrome (MHS) in Pigs Genetika 29:1009-1013, 1993. Pubmed reference: 8370496.
Cheah, K.S., Cheah, A.M., Lahucky, R., Mojto, J., Kovac, L. :
Prediction of Meat Quality in Live Pigs Using Stress- Susceptible and Stress-Resistant Animals Meat Science 34:179-189, 1993.
Claxtongill, M.S., Cornickseahorn, J.L., Gamboa, J.C., Boatright, B.S. :
Suspected Malignant Hyperthermia Syndrome in a Miniature Pot- Bellied Pig Anesthetized with Isoflurane Journal of the American Veterinary Medical Association 203:1434-1436, 1993. Pubmed reference: 8276704.
Decanniere, C., Vanhecke, P., Vanstapel, F., Ville, H., Geers, R. :
Metabolic Response to Halothane in Piglets Susceptible to Malignant Hyperthermia - An Invivo P-31-NMR Study Journal of Applied Physiology 75:955-962, 1993. Pubmed reference: 8226501.
Dickson, D. :
DNA Testing Helps British Bring Better Pig to Market Nature 362:688, 1993. Pubmed reference: 8469276. DOI: 10.1038/362688b0.
Duthie, G.G., Arthur, J.R. :
Free Radicals and Calcium Homeostasis - Relevance to Malignant Hyperthermia Free Radical Biology and Medicine 14:435-442, 1993. Pubmed reference: 8468027.
Enfalt, A.C., Lundstrom, K., Engstrand, U. :
Early Post-Mortem pH Decrease in Porcine M-Longissimus dorsi of PSE, Normal and DFD Quality Meat Science 34:131-143, 1993.
Falkenberg, H., Matthes, W., Schwerin, M. :
MHS-Assays and CK-Assays and Their Relation to Each Other and to Performances in Pig Archiv Fur Tierzucht - Archives of Animal Breeding 36:175-188, 1993.
Fewson, D., Rathfelder, A., Muller, E. :
Experiments Concerning the Correlations Between Meat Content, Meat Quality, and Stress Resistance in Different Origins of Pigs .1. Significance of the Morphology of the Musculus Longissimus Dorsi Zuchtungskunde 65:284-296, 1993.
Fiedler, I., Ender, K., Wicke, M., Vonlengerken, G. :
Relationships Between Microstructure of Muscle Tissue and Stress Sensibility in Landrace Pigs Archiv Fur Tierzucht - Archives of Animal Breeding 36:525-538, 1993.
Fletcher, J.E., Calvo, P.A., Rosenberg, H. :
Phenotypes Associated with Malignant Hyperthermia Susceptibility in Swine Genotyped as Homozygous or Heterozygous for the Ryanodine Receptor Mutation British Journal of Anaesthesia 71:410-417, 1993. Pubmed reference: 8398525.
Foster, P.S., Denborough, M.A. :
The Effect of Calcium Channel Antagonists and BAY K-8644 on Calcium Fluxes of Malignant Hyperpyrexia-Susceptible Muscle International Journal of Biochemistry 25:495-504, 1993. Pubmed reference: 7682190.
Gareau, P.J., Janzen, E.G., Towner, R.A., Stewart, W.A. :
Invivo P-31 NMR Spectroscopy Studies of Halothane Induced Porcine Stress Syndrome - No Effect of C-Phenyl N-tert-Butyl Nitrone (PBN) Free Radical Research Communications 19:43-50, 1993. Pubmed reference: 8225033.
Garlik, J., Poltarsky, J., Galik, R., Balogh, Z. :
Utilization of Crude Protein in Pigs Differently Responding to Halothane Anesthesia Zivocisna Vyroba 38:253-260, 1993.
Hald, T.L. :
Early Recognition of DFD Carcasses Fleischwirtschaft 73:140, 1993.
Houde, A., Pommier, S.A. :
Use of Polymerase Chain Reaction Technology to Detect a Mutation Associated with Malignant Hyperthermia in Different Pig Tissues Meat Science 33:349-358, 1993.
Houde, A., Pommier, S.A., Roy, R. :
Detection of the Ryanodine Receptor Mutation Associated with Malignant Hyperthermia in Purebred Swine Populations Journal of Animal Science 71:1414-1418, 1993. Pubmed reference: 8392045.
Klont, R.E., Lambooy, E., Vanlogtestijn, J.G. :
Effect of Preslaughter Anesthesia on Muscle Metabolism and Meat Quality of Pigs of Different Halothane Genotypes Journal of Animal Science 71:1477-1485, 1993. Pubmed reference: 8100812.
Kochs, E., Hoffman, W.E., Esch, J.S.A. :
Improvement of Brain Electrical Activity During Treatment of Porcine Malignant Hyperthermia with Dantrolene British Journal of Anaesthesia 71:881-884, 1993. Pubmed reference: 8280559.
Kuciel, J., Dvorak, J., Nebola, M. :
Adenosine Deaminase Polymorphism in Stress Positive and Stress Negative Pigs Zivocisna Vyroba 38:577-581, 1993.
Lahucky, R., Mojto, J., Poltarsky, J., Miri, A., Renou, J.P., Talmant, A., Monin, G. :
Evaluation of Halothane Sensitivity and Prediction of Post- Mortem Muscle Metabolism in Pigs from a Muscle Biopsy Using P- 31 NMR Spectroscopy Meat Science 33:373-384, 1993.
Lamers, J.M.J., Duncker, D.J., Bezstarosti, K., Mcfalls, E.O., Sassen, L.M.A., Verdouw, P.D. :
Increased Activity of the Sarcoplasmic Reticular Calcium Pump in Porcine Stunned Myocardium Cardiovascular Research 27:520-524, 1993. Pubmed reference: 8387889.
Leeb, T., Schmolzl, S., Brem, G., Brenig, B. :
Genomic Organization of the Porcine Skeletal Muscle Ryanodine Receptor (Ryr1) Gene Coding Region 4624 to 7929 Genomics 18:349-354, 1993. Pubmed reference: 8288238. DOI: 10.1006/geno.1993.1475.
Maclennan, D.H., Higashida, H., Chen, S.R.W., Yoshioka, T., Mikoshiba, K. :
The Role of the Calcium Release Channel of Skeletal Muscle Sarcoplasmic Reticulum in Malignant Hyperthermia Molecular Basis of Ion Channels and Receptors Involved in Nerve Excitation, Synaptic Transmission and Muscle Contraction 707:294-304, 1993.
Mammar, M.S., Vignon, X., Rock, E., Mathieu, F., Gandemer, G. :
Analysis of Lipid Composition of Sarcoplasmic Reticulum Membranes from Normal and Malignant Hyperthermic Pig Skeletal Muscle Biochemistry and Cell Biology - Biochimie et Biologie Cellulaire 71:324-330, 1993. Pubmed reference: 8123249.
Marolf, C.J., Schultz, B.D., Clemens, E.T. :
Epinephrine Effects on Gastrin and Gastric Secretions in Normal and Stress-Susceptible Pigs and in Dogs Comparative Biochemistry and Physiology C - Comparative Pharmacology and Toxicology 106:367-370, 1993.
Mayr, B., Schellander, K., Flekna, G., Panajotov, A. :
PCR-Analysis of the Ryanodine Receptor Gene for MHS- Genotyping in Austrian Pig Breeds .2. Genotype and Allele- Frequencies in Edelschwein and Landrasse Wiener Tierarztliche Monatsschrift 80:261-263, 1993.
Mcpherson, P.S., Campbell, K.P. :
The Ryanodine Receptor/Ca2+ Release Channel Journal of Biological Chemistry 268:13765-13768, 1993. Pubmed reference: 8390976.
Moesgaard, B., Christensen, V.G., Jorgensen, P.F., Quistorff, B., Terkelsen, I. :
Comments on Halothane Gene Carriers in Pigs American Journal of Veterinary Research 54:816, 1993. Pubmed reference: 8347246.
Nystrom, P.E., Andersson, K. :
Halothane Gene Effects on Reproduction, Production and Organ Weights in Pigs Acta Agriculturae Scandinavica Section A - Animal Science 43:201-206, 1993.
Obrien, P.J., Shen, H., Cory, C.R., Zhang, X. :
Use of a DNA-Based Test for the Mutation Associated with Porcine Stress Syndrome (Malignant Hyperthermia) in 10,000 Breeding Swine Journal of the American Veterinary Medical Association 203:842-851, 1993. Pubmed reference: 7901188.
Oliver, M.A., Gispert, M., Diestre, A. :
The Effects of Breed and Halothane Sensitivity on Pig Meat Quality Meat Science 35:105-118, 1993.
Pommier, S.A., Houde, A. :
Effect of the Genotype for Malignant Hyperthermia as Determined by a Restriction Endonuclease Assay on the Quality Characteristics of Commercial Pork Loins Journal of Animal Science 71:420-425, 1993. Pubmed reference: 8440662.
Reiner, G., Hecht, W., Herzog, A., Dzapo, V. :
Reproductivity of Sows with Differing MHS-Genotype Deutsche Tierarztliche Wochenschrift 100:144-146, 1993. Pubmed reference: 8486090.
Rempel, W.E., Lu, M., Elkandelgy, S., Kennedy, C.F.H., Irvin, L.R., Mickelson, J.R., Louis, C.F. :
Relative Accuracy of the Halothane Challenge Test and a Molecular Genetic Test in Detecting the Gene for Porcine Stress Syndrome Journal of Animal Science 71:1395-1399, 1993. Pubmed reference: 8392044.
Rock, E., Motta, C., Vignon, X., Kozakribbens, G. :
Fluidity State of Lymphocyte Plasma Membrane in Malignant Hyperthermia Susceptible Pigs and Humans Acta Anaesthesiologica Scandinavica 37:488-492, 1993. Pubmed reference: 8356862.
Rosel, U., Szentkuti, L. :
In vitro Caffeine Test on Porcine Skeletal Muscle Samples Deutsche Tierarztliche Wochenschrift 100:25-28, 1993. Pubmed reference: 8428567.
Schaefer, A.L., Murray, A.C., Tong, A.K.W., Jones, S.D.M., Sather, A.P. :
The Effect of Ante-Mortem Electrolyte Therapy on Animal Physiology and Meat Quality in Pigs Segregating at the Halothane Gene Canadian Journal of Animal Science 73:231-240, 1993.
Schellander, K., Mayr, B., Siegl, G. :
PCR-Analysis of the Ryanodine Receptor Gene for MHS- Genotyping in Austrian Pig Breeds .1 Wiener Tierarztliche Monatsschrift 80:97-99, 1993.
Scholz, J., Steinfath, M., Roewer, N., Patten, M., Troll, U., Schmitz, W., Scholz, H., Esch, J.S.A. :
Biochemical Changes in Malignant Hyperthermia Susceptible Swine - Cyclic AMP, Inositol Phosphates, alpha-1, beta-1- Adrenoceptor and beta-2-Adrenoceptor in Skeletal and Cardiac Muscle Acta Anaesthesiologica Scandinavica 37:575-583, 1993. Pubmed reference: 8213023.
Schulman, S.R. :
The Sixth International Malignant Hyperthermia Workshop Anesthesiology 78:626, 1993.
Shomer, N.H., Louis, C.F., Fill, M., Litterer, L.A., Mickelson, J.R. :
Reconstitution of Abnormalities in the Malignant Hyperthermia- Susceptible Pig Ryanodine Receptor American Journal of Physiology 264:C125-C135, 1993. Pubmed reference: 7679249.
Sorrentino, V., Volpe, P. :
Ryanodine Receptors - How Many, Where and Why Trends in Pharmacological Sciences 14:98-103, 1993. Pubmed reference: 8387707.
Strand, M.A., Louis, C.F., Mickelson, J.R. :
Phosphorylation of the Porcine Skeletal and Cardiac Muscle Sarcoplasmic Reticulum Ryanodine Receptor Biochimica et Biophysica Acta 1175:319-326, 1993. Pubmed reference: 8435448.
Vanlaack, R.L.J.M., Faustman, C., Sebranek, J.G. :
Pork Quality and the Expression of Stress Protein Hsp-70 in Swine Journal of Animal Science 71:2958-2964, 1993. Pubmed reference: 8270516.
Ville, H., Bertels, S., Geers, R., Janssens, S., Goedseels, V., Parduyns, G., Vanbael, J., Goossens, K., Bosschaerts, L., Deley, J., Heylen, L. :
Electrocardiogram Parameters of Piglets During Housing, Handling and Transport Animal Production 56:211-216, 1993.
Warnants, N., Eeckhout, W., Boucque, C.V. :
Serum Pyruvate Kinase and Its Relation to Stress Susceptibility in Pigs Journal of Animal Breeding and Genetics - Zeitschrift Fur Tierzuchtung und Zuchtungsbiologie 110:357-362, 1993.
Wedel, D.J., Gammel, S.A., Milde, J.H., Iaizzo, P.A. :
Delayed Onset of Malignant Hyperthermia Induced by Isoflurane and Desflurane Compared with Halothane in Susceptible Swine Anesthesiology 78:1138-1144, 1993. Pubmed reference: 8512107.
Wicke, M., Vonlengerken, G., Maak, S., Fiedler, I. :
Prediction of PSE-Meat by Biochemical and Morphological Traits of Skeletal Muscle in Living Pigs Archiv Fur Tierzucht - Archives of Animal Breeding 36:631-638, 1993.
Wittmann, W., Peschke, W., Littmann, E., Behringer, J., Birkenmaier, S., Dovc, P., Forster, M. :
Fattening and Carcass Performance Traits of German Landrace Castrates Genetically Differentiated by the MHS-Gene-Test Zuchtungskunde 65:197-205, 1993.
1992 Allen, P.D., Lopez, J.R., Sanchez, V., Ryan, J.F., Sreter, F.A. :
EU-4093 Decreases Intracellular <Ca2+> in Skeletal Muscle Fibers from Control and Malignant Hyperthermia Susceptible Swine Anesthesiology 76:132-138, 1992. Pubmed reference: 1729917.
Arai, M., Otsu, K., Maclennan, D.H., Periasamy, M. :
Regulation of Sarcoplasmic Reticulum Gene Expression During Cardiac and Skeletal Muscle Development American Journal of Physiology 262:C614-C620, 1992. Pubmed reference: 1372478.
Boles, J.A., Parrish, F.C., Huiatt, T.W., Robson, R.M. :
Effect of Porcine Stress Syndrome on the Solubility and Degradation of Myofibrillar Cytoskeletal Proteins Journal of Animal Science 70:454-464, 1992. Pubmed reference: 1548208.
Brem, G., Brenig, B. :
Molecular Genotype Diagnosis of the Malignant Hyperthermia Syndrome for Efficient Breeding of Stress-Resistant Pigs Wiener Tierarztliche Monatsschrift 79:301-305, 1992.
Brenig, B., Brem, G. :
Molecular Cloning and Analysis of the Porcine Halothane Gene Archiv Fur Tierzucht - Archives of Animal Breeding 35:129-135, 1992.
Brenig, B., Brem, G. :
Genomic Organization and Analysis of the 5' End of the Porcine Ryanodine Receptor Gene (ryrl) FEBS Letters 298:277-279, 1992. Pubmed reference: 1312025.
Casteels, M., Bosschaerts, L. :
Instrumental Detection of PSE-Carcasses in the Slaughterline Landbouwtijdschrift - Revue de L Agriculture 45:1115-1127, 1992.
Chowdhary, B.P., Harbitz, I., Davies, W., Gustavsson, I. :
Localization of the Calcium Release Channel Gene in Cattle and Horse by In situ Hybridization - Evidence of a Conserved Synteny with Glucose Phosphate Isomerase Animal Genetics 23:43-50, 1992. Pubmed reference: 1315127.
Claes, V., Chaput, M., Kettmann, R., Burny, A., Thielemans, M.F., Bodart, C. :
Molecular Diagnosis of Pig Malignant Hyperthermia Landbouwtijdschrift - Revue de L Agriculture 45:505-512, 1992.
Coppieters, W., Vanzeveren, A., Vandeweghe, A., Peelman, L., Bouquet, Y. :
Direct Genotyping of Stress Susceptibility and Resistance in Pigs by Means of a DNA Test Vlaams Diergeneeskundig Tijdschrift 61:68-72, 1992.
Doize, F., Martineaudoize, B., Deroth, L. :
Total Plasma Creatine Kinase Activity in Relation to Phi and PGD Phenotypes in Normal and Stress-Susceptible Landrace Pigs Canadian Veterinary Journal - Revue Veterinaire Canadienne 33:263-264, 1992.
Duthie, G.G., Wahle, K.W.J., Harris, C.I., Arthur, J.R., Morrice, P.C. :
Lipid Peroxidation, Antioxidant Concentrations, and Fatty Acid Contents of Muscle Tissue from Malignant Hyperthermia- Susceptible Swine Archives of Biochemistry and Biophysics 296:592-596, 1992. Pubmed reference: 1632646.
Dvorak, J. :
Genotypes at the HAL Locus and Reproductive Traits in Pigs of the Breeding Population of the Landrace Breed Zivocisna Vyroba 37:193-203, 1992.
Dvorak, J., Tesarova, L., Ingr, I. :
Incidence of PSE Meat in Pigs with Different ADA (Adenosine Deaminase) Phenotypes Zivocisna Vyroba 37:31-37, 1992.
Fink, H.S., Maak, S., Vonlengerken, G., Till, U. :
Abnormalities in the Regulation of Blood Platelet Free Cytosolic Calcium in Malignant Hyperthermia .2. Pig Platelets Cell Calcium 13:157-162, 1992. Pubmed reference: 1576636.
Foster, P.S., Hopkinson, K.C., Denborough, M.A. :
Propofol Anaesthesia in Malignant Hyperpyrexia Susceptible Swine Clinical and Experimental Pharmacology & Physiology 19:183-186, 1992. Pubmed reference: 1521353.
Gabrisova, E., Cizova, D., Hony, J. :
Haplotypes of the Linkage Group S-HAL-GPI-H-A1BG-PGD in Breeding Pigs of the Prestice Black-Pied Breed for Stress Resistance Zivocisna Vyroba 37:625-632, 1992.
Gaillard, S., Rock, E., Vignon, X., Dufourc, E.J., Renou, J.P. :
P-31 NMR and Freeze Fracture Studies of Sarcoplasmic Reticulum Membranes from Normal and Malignant Hyperthermic Pigs - Effect of Halothane and Dantrolene Archives of Biochemistry and Biophysics 294:154-159, 1992. Pubmed reference: 1550341.
Galik, R., Poltarsky, J., Garlik, J. :
Nutrient Digestibility and Nitrogen Utilization by Pigs in Relation to Their Response to Halothane Anaesthesia Zivocisna Vyroba 37:263-268, 1992.
Gallant, E.M., Lentz, L.R. :
Excitation-Contraction Coupling in Pigs Heterozygous for Malignant Hyperthermia American Journal of Physiology 262:C422-C426, 1992. Pubmed reference: 1539630.
Geers, R., Decanniere, C., Ville, H., Vanhecke, P., Goedseels, V., Bosschaerts, L., Deley, J., Janssens, S., Nierynck, W. :
Identification of Halothane Gene Carriers by Use of In Vivo P- 31 Nuclear Magnetic Resonance Spectroscopy in Pigs American Journal of Veterinary Research 53:1711-1713, 1992. Pubmed reference: 1416381.
Geers, R., Decanniere, C., Ville, H., Vanhecke, P., Goedseels, V., Vanstapel, F., Bosschaerts, L., Deley, J., Zhang, W.G., Janssens, S. :
In vivo Muscle P-31 Nuclear Magnetic Resonance Spectroscopy During Treatment of Halothane-Sensitive and Halothane- Nonsensitive Pigs American Journal of Veterinary Research 53:613-616, 1992. Pubmed reference: 1586038.
Geers, R., Ville, H., Janssens, S., Goedseels, V., Goossens, K., Parduyns, G., Vanbael, J., Bosschaerts, L., Heylen, L. :
Changes of Body Temperatures of Piglets as Related to Halothane Sensitivity and Treadmill Exercise Journal of Thermal Biology 17:125-128, 1992.
Gerdes, C., Richter, A., Annies, R., Loscher, W. :
Increase of Serotonin in Plasma During Onset of Halothane- Induced Malignant Hyperthermia in Pigs European Journal of Pharmacology 220:91-94, 1992. Pubmed reference: 1425984.
Grobet, L., Hanset, R., Dasnois, C. :
Halothane Challenge Test and Genotype at the Ryanodine Receptor Locus (RYR1) in Crossbred Pietrain Pigs Annales de Medecine Veterinaire 136:249-257, 1992.
Harbitz, I., Kristensen, T., Bosnes, M., Kran, S., Davies, W. :
DNA Sequence of the Skeletal Muscle Calcium Release Channel cDNA and Verification of the Arg(615)->Cys(615) Mutation, Associated with Porcine Malignant Hyperthermia, in Norwegian Landrace Pigs Animal Genetics 23:395-402, 1992. Pubmed reference: 1329581.
Harrison, G.G., Isaacs, H. :
Malignant Hyperthermia - An Historical Vignette Anaesthesia 47:54-56, 1992. Pubmed reference: 1536407.
Henckel, P., Jorgensen, P.F., Jensen, P. :
Glycogen Content, Buffering Capacity and Resting pH in Live Muscles of Pigs of Different Halothane Genotypes (A Pilot Project) Meat Science 32:131-138, 1992.
Hill, M.R. :
Porcine Stress Deaths Veterinary Record 130:59, 1992. Pubmed reference: 1546438.
Hogan, K., Couch, F., Powers, P.A., Gregg, R.G. :
A Cysteine-for-Arginine Substitution (R614C) in the Human Skeletal Muscle Calcium Release Channel Cosegregates with Malignant Hyperthermia Anesthesia and Analgesia 75:441-448, 1992. Pubmed reference: 1510267.
Holland, M., Williams, J.H., Lee, J.C. :
W-7, a Calmodulin Antagonist, and Contracture of Malignant Hyperthermia Susceptible Skeletal Muscle Comparative Biochemistry and Physiology C - Comparative Pharmacology and Toxicology 101:383-388, 1992.
Hopkins, P.M., Ellis, F.R., Halsall, P.J. :
Inconsistency of Data Linking the Ryanodine Receptor and Malignant Hyperthermia Genes Anesthesiology 76:659-660, 1992. Pubmed reference: 1610471.
Hovenier, R., Kanis, E., Vanasseldonk, T., Westerink, N.G. :
Genetic Parameters of Pig Meat Quality Traits in a Halothane Negative Population Livestock Production Science 32:309-321, 1992.
Hughes, I.P., Moran, C., Nicholas, F.W. :
PCR Genotyping of the Ryanodine Receptor Gene for a Putative Causal Mutation for Malignant Hyperthermia in Australian Pigs Journal of Animal Breeding and Genetics - Zeitschrift Fur Tierzuchtung und Zuchtungsbiologie 109:465-476, 1992.
Joffe, M., Savage, N., Silove, M. :
The Biochemistry of Malignant Hyperthermia - Recent Concepts International Journal of Biochemistry 24:387-398, 1992. Pubmed reference: 1312953.
Kuciel, J., Dvorak, J. :
A Change in Allele and Genotype Frequencies of Halothane Locus in Boars of the Landrace Breed Zivocisna Vyroba 37:633-638, 1992.
Kurlan, R., Klawans, H.L., Goetz, C.G., Tanner, C.M. :
The Malignant Hyperthermic Syndromes Textbook of Clinical Neuropharmacology and Therapeutics, 2nd Edition :405-411, 1992.
Larach, M.G. :
Malignant Hyperthermia Science 257:11-12, 1992. Pubmed reference: 1621085.
Maak, S., Fink, H.S., Vonlengerken, G., Hofmann, J.G. :
Halothane Susceptibility and Calcium Homeostasis of Porcine Blood Platelets Journal of Animal Breeding and Genetics - Zeitschrift Fur Tierzuchtung und Zuchtungsbiologie 109:216-220, 1992.
MacLennan, D.H., Otsu, K., Fujii, J., Zorzato, F., Phillips, M.S., O'Brien, P.J., Archibald, A.L., Britt, B.A., Gillard, E.F., Worton, R.G. :
The role of the skeletal muscle ryanodine receptor gene in malignant hyperthermia. Symp Soc Exp Biol 46:189-201, 1992. Pubmed reference: 1341035.
Mackenzie, A., Maclennan, D.H. :
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Multiple Restriction Fragment Length Polymorphisms in the Porcine Calcium Release Channel Gene (CRC) - Assignment to the Halothane (HAL) Linkage Group Animal Genetics 23:257-262, 1992. Pubmed reference: 1354420.
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The Effects of Alpha-Adrenergic and Beta-Adrenergic Blockers and Epinephrine in Halothane-Sensitive Pigs in Their Response to Halothane Tierarztliche Umschau 47:371-376, 1992.
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The Effect of the Malignant Hyperthermia Genotype as Determined by a Restriction Endonuclease Assay on Carcass Characteristics of Commercial Crossbred Pigs Canadian Journal of Animal Science 72:973-976, 1992.
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Atypical Reactions to Halothane in a Subgroup of Homozygous Malignant Hyperthermia(MH)-Susceptible Pigs - Indication of a Heterogenous Genetic Basis for the Porcine Syndrome Deutsche Tierarztliche Wochenschrift 99:401-406, 1992. Pubmed reference: 1425316.
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Associations Between Blood Marker Loci and Stress Susceptibility in Pigs Journal of Animal Breeding and Genetics - Zeitschrift Fur Tierzuchtung und Zuchtungsbiologie 109:301-310, 1992.
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The Influence of Immobilization Stress on Natural Killer Cytotoxic Activity in Halothane Susceptible and Resistant Pigs Veterinary Immunology and Immunopathology 31:371-376, 1992. Pubmed reference: 1589959.
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Diagnosis of Stress Susceptibility and Deficiency in Nature of Meat in Living Pigs - Review Monatshefte Fur Veterinarmedizin 47:479-486, 1992.
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Multiple Effects of Ryanodine on Intracellular Free Ca2+ in Smooth Muscle Cells from Bovine and Porcine Coronary Artery - Modulation of Sarcoplasmic Reticulum Function British Journal of Pharmacology 105:903-911, 1992. Pubmed reference: 1504718.
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Selection of Genetically Homozygous Stress-Resistant German Landrace Pigs by Means of Marker Genes Archiv Fur Tierzucht - Archives of Animal Breeding 35:119-127, 1992.
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1991 Ayoub, S., Berson, G., Rock, E., Younes, A. :
Mitochondrial Nucleotide Translocase from Skeletal Muscle of Halothane Sensitive Pigs - An Electrophoretic Study Cell Biochemistry and Function 9:193-199, 1991. Pubmed reference: 1752024. DOI: 10.1002/cbf.290090307.
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Sensory and Processing Properties of Cured Semimembranosus Muscle from Stress-Susceptible Pigs Treated with Porcine Somatotropin Journal of Animal Science 69:4049-4054, 1991. Pubmed reference: 1778818.
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Some Ethological and Physiological Indicators of MHS in Pigs Journal of Animal Breeding and Genetics - Zeitschrift Fur Tierzuchtung und Zuchtungsbiologie 108:315-318, 1991.
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Abnormal Rapid Ca2+ Release from Sarcoplasmic Reticulum of Malignant Hyperthermia Susceptible Pigs Biochimica et Biophysica Acta 1064:175-183, 1991. Pubmed reference: 1645197.
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Mapping of Genes Belonging to the Halothane Linkage Group in Pigs Using In situ Hybridization Genetics Selection Evolution 23:S96-S99, 1991.
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Calcium ATPase in the Sarcoplasmic Reticulum of Muscle from Normal and Malignant Hyperthermia Susceptible Pigs Neuroscience Letters 131:187-192, 1991. Pubmed reference: 1837071.
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Dietary Vitamin-E Decreases ESR Signal Intensity in Hepatic Microsomal Preparations from Malignant Hyperthermia Susceptible Pigs Free Radical Research Communications 14:133-137, 1991. Pubmed reference: 1648019.
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Influence of the Administration of Magnesium-Aspartate- Hydrochloride on Porcine-Stress-Syndrome Magnesium - Bulletin 13:103-106, 1991.
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Ryanodine Receptor in Different Malignant Hyperthermia- Susceptible Porcine Muscles American Journal of Physiology 260:C58-C66, 1991. Pubmed reference: 1824808.
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Comparison of North American and European Malignant Hyperthermia Group Halothane Contracture Testing Protocols in Swine Acta Anaesthesiologica Scandinavica 35:483-487, 1991. Pubmed reference: 1897341.
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Fatty Acids Markedly Lower the Threshold for Halothane- Induced Calcium Release from the Terminal Cisternae in Human and Porcine Normal and Malignant Hyperthermia Susceptible Skeletal Muscle Life Sciences 49:1651-1657, 1991. Pubmed reference: 1943469.
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The Effect of Azumolene on Hypercontractility and Sarcoplasmic Reticulum Ca-2+-Dependent ATPase Activity of Malignant Hyperpyrexia-Susceptible Porcine Skeletal Muscle Clinical and Experimental Pharmacology & Physiology 18:489-495, 1991. Pubmed reference: 1833102.
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A Comparison of Some Muscle Metabolites in Stress Susceptible and Resistant Landrace Gilts After Halothane Exposure or Exercise Stress Meat Science 30:337-349, 1991.
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Visceral Losses of Desflurane, Isoflurane, and Halothane in Swine Anesthesia and Analgesia 73:209-212, 1991. Pubmed reference: 1854035.
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Malignant Hyperthermia - An Anaesthetic Complication Monatshefte Fur Veterinarmedizin 46:614-617, 1991.
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Calcium Handling by Platelets from Normal and Malignant Hyperthermia-Susceptible Pigs Life Sciences 48:1471-1476, 1991. Pubmed reference: 2011050.
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The Measurement of Light Scattering and Electrical Conductivity for the Prediction of PSE Pig Meat At Various Times Post Mortem Meat Science 29:141-151, 1991.
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The Effect of the Halothane Gene on Pork Production and Meat Quality of Pigs Reared Under Commercial Conditions Canadian Journal of Animal Science 71:959-967, 1991.
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Effects of Caffeine, Halothane, Succinylcholine, Phenylephrine and Isoproterenol on Myocardial Force of Contraction of Malignant Hyperthermia Susceptible Swine Acta Anaesthesiologica Scandinavica 35:320-325, 1991. Pubmed reference: 1853693.
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Gas Anaesthesia of Slaughter Pigs .1. Stunning Experiments Under Laboratory Conditions with Fat Pigs of Known Halothane Reaction Type - Meat Quality, Animal Protection Fleischwirtschaft 71:1063-1068, 1991.
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Reduction of Stress and Stress Susceptibility in Pigs As Prerequisite for Qualitatively and Quantitatively High Results .2. Possibilities to Reduce Stress Susceptibility and Meat Quality Deficiencies in Pigs Archiv Fur Tierzucht - Archives of Animal Breeding 34:241-247, 1991.
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Relationship Between Muscle Metabolism in the Musculus Longissimus and Halothane Susceptibility Archiv Fur Tierzucht - Archives of Animal Breeding 34:553-560, 1991.
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Endothelin Mediates Ca Influx and Release in Porcine Coronary Smooth Muscle Cells American Journal of Physiology 260:C771-C777, 1991. Pubmed reference: 1850196.
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The Porcine Phicdna Linked to the Halothane Gene Detects a Noti RFLP in Normal and Malignant Hyperthermia Susceptible Pigs Nucleic Acids Research 18:388, 1990.
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The Porcine Phicdna Linked to the Halothane Gene Detects a Hindiii and Xbai RFLP in Normal and Malignant Hyperthermia Susceptible Pigs Nucleic Acids Research 18:388, 1990.
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Prediction of the Halothane (Hal) Genotypes by Means of Linked Marker Loci (Phi, Po2, Pgd) in Quebec Landrace Pigs Canadian Journal of Veterinary Research-Revue Canadienne de Recherche Veterinaire 54:397-399, 1990. Pubmed reference: 2249173.
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Spin Trapping of Free Radicals and Lipid Peroxidation in Microsomal Preparations from Malignant Hyperthermia Susceptible Pigs Free Radical Research Communications 8:93-99, 1990. Pubmed reference: 2156750.
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Halothane Sensitivity of Young Pigs Invivo and Invitro American Journal of Physiology 259:R133-R138, 1990. Pubmed reference: 2375422.
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Importance of Fasting in the Lymphocyte Calcium Test for Malignant Hyperthermia Acta Anaesthesiologica Scandinavica 34:636-639, 1990. Pubmed reference: 2275324.
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Stress in Domestic Pigs Journal of Animal Breeding and Genetics-Zeitschrift Fur Tierzuchtung und Zuchtungsbiologie :69-79, 1990.
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Estimation of the Frequency of the Halothane Gene and Its Effects in Landrace and Yorkshire Pigs in Ontario Canadian Journal of Animal Science 70:73-79, 1990.
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Concurrence of Malignant Hyperthermia and Congenital Abnormalities Muscle & Nerve 13:915-917, 1990. Pubmed reference: 2233848. DOI: 10.1002/mus.880131005.
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Identifying PSE Meat by Means of Electric Conductance Veterinarni Medicina 35:43-48, 1990.
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Porcine Stress Syndrome - An Animal Model for the Neuroleptic Malignant Syndrome Biological Psychiatry 28:58-62, 1990. Pubmed reference: 2115811.
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Halothane Increases Cytosolic Ca-2+ and Inhibits Na+/H+ Exchange in L6 Muscle Cells Journal of Pharmacology and Experimental Therapeutics 254:552-559, 1990. Pubmed reference: 2384885.
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The Minimum Alveolar Concentration (Mac) and Hemodynamic Effects of Halothane, Isoflurane, and Sevoflurane in Newborn Swine Anesthesiology 73:717-721, 1990. Pubmed reference: 2221440.
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Ryanodine Receptor Gene Is a Candidate for Predisposition to Malignant Hyperthermia Nature 343:559-561, 1990. Pubmed reference: 1967823. DOI: 10.1038/343559a0.
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Compensatory Increase in Calcium Extrusion Activity of Untreated Lymphocytes from Swine Susceptible to Malignant Hyperthermia American Journal of Veterinary Research 51:1038-1043, 1990. Pubmed reference: 2389880.
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Stress - Biological and Biomedical Considerations Journal of Animal Breeding and Genetics-Zeitschrift Fur Tierzuchtung und Zuchtungsbiologie :57-68, 1990.
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Multiple-Pulse Stimulation and Dantrolene in Malignant Hyperthermia Muscle & Nerve 13:904-908, 1990. Pubmed reference: 2233846. DOI: 10.1002/mus.880131003.
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The Prognostical Significance of Ham Temperature Obtained During Halothane Testing in Regard to Meat Quality in Pigs Fleischwirtschaft 70:1325-1328, 1990.
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Influence of the Halothane Gene and Effects of Halothane on the Osmotic Fragility of Erythrocytes in Pigs Journal of Animal Physiology and Animal Nutrition-Zeitschrift Fur Tierphysiologie Tierernahrung und Futtermittelkunde 63:149-154, 1990.
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Abnormal Fluidity State in Membranes of Malignant Hyperthermia Pig Skeletal Muscle Archives of Biochemistry and Biophysics 281:36-40, 1990. Pubmed reference: 2166478.
Rundgren, M., Lundstrom, K., Edfors-Lilja, I. :
A Within-Litter Comparison of the 3 Halothane Genotypes .2. Performance, Carcass Quality, Organ Development and Long-Term Effects of Transportation and Amperozide Livestock Production Science 26:231-243, 1990.
Rundgren, M., Lundstrom, K., Edfors-Lilja, I., Juneja, R.K. :
A Within-Litter Comparison of the 3 Halothane Genotypes .1. Piglet Performance and Effects of Transportation and Amperozide Treatment At 12 Weeks of Age Livestock Production Science 26:137-153, 1990.
Sather, A.P., Schaefer, A.L., Tong, A.K.W., Gariepy, C., Zawadski, S.M. :
Muscle and Rectal Temperature Response Curves to a Short-Term Halothane Challenge in 8-Week-Old Piglets with Known Genotype at the Halothane Locus Canadian Journal of Animal Science 70:9-14, 1990.
Schaefer, A.L., Doornenbal, H., Sather, A.P., Tong, A.K.W., Jones, S.D.M., Murray, A.C. :
The Use of Blood Serum Components in the Identification of Stress-Susceptible and Carrier Pigs Canadian Journal of Animal Science 70:845-855, 1990.
Sufit, R.L., Kreul, J.F., Bellay, Y.M., Helmer, P., Brunson, D.B., Will, J. :
Doxacurium and Mivacurium Do Not Trigger Malignant Hyperthermia in Susceptible Swine Anesthesia and Analgesia 71:285-287, 1990. Pubmed reference: 2144100.
Uhrin, P. :
Post-Mortal Metabolism of Glycogen in the Muscles of Healthy Pigs and Pigs with Malignant Hyperthermia Syndrome Veterinarni Medicina 35:403-409, 1990. Pubmed reference: 2087801.
Vanarendonk, J.A.M., Kennedy, B.W. :
Efficiency of Selection Strategies for Halothane-Negative Gene Journal of Animal Science 68:1569-1576, 1990. Pubmed reference: 2384358.
Vanzeveren, A., Bouquet, Y., Vandeweghe, A., Lampo, P., Peelman, L., Coppieters, W. :
Stress Susceptibility in Belgian Landrace Pigs - Zootechnical Implications and Blood Marker Determinations As a Tool for a More Efficient Selective Reduction Vlaams Diergeneeskundig Tijdschrift 59:169-174, 1990.
Warriss, P.D., Brown, S.N., Rolph, T.P., Kestin, S.C. :
Interactions Between the Beta-Adrenergic Agonist Salbutamol and Genotype on Meat Quality in Pigs Journal of Animal Science 68:3669-3676, 1990. Pubmed reference: 2262419.
Yasuda, N., Targ, A.G., Eger, E.I., Johnson, B.H., Weiskopf, R.B. :
Pharmacokinetics of Desflurane, Sevoflurane, Isoflurane, and Halothane in Pigs Anesthesia and Analgesia 71:340-348, 1990. Pubmed reference: 2400116.
Yeh, H.J.C., Moody, E.J., Skolnick, P. :
Halothane and Anaesthesia Nature 346:227, 1990. Pubmed reference: 2374588. DOI: 10.1038/346227b0.
Yerle, M., Archibald, A.L., Dalens, M., Gellin, J. :
Localization of the PGD and TGF beta-1 loci to pig chromosome 6q. Anim Genet 21:411-7, 1990. Pubmed reference: 2090012.
1989 Blasco, A., Webb, A.J. :
Genetic variation in reaction time to halothane exposure Animal Production 49:117-121, 1989.
Chowdhary, B.P., Harbitz, I., Makinen, A., Davies, W., Gustavsson, I. :
Localization of the Glucose Phosphate Isomerase Gene to the P12->Q21 Segment of Chromosome-6 in Pig by Insitu Hybridization Hereditas 111:73-78, 1989. Pubmed reference: 2793514.
Dershwitz, M., Sreter, F.A., Ryan, J.F. :
Ketamine Does Not Trigger Malignant Hyperthermia in Susceptible Swine Anesthesia and Analgesia 69:501-503, 1989. Pubmed reference: 2782651.
Ervasti, J.M., Mickelson, J.R., Louis, C.F. :
Transverse tubule calcium regulation in malignant hyperthermia. Arch Biochem Biophys 269:497-506, 1989. Pubmed reference: 2537601.
Foster, P.S., Gesini, E., Claudianos, C., Hopkinson, K.C., Denborough, M.A. :
Inositol 1,4,5,-Trisphosphate Phosphatase Deficiency and Malignant Hyperpyrexia in Swine Lancet 2:124-127, 1989. Pubmed reference: 2567894.
Foster, P.S., White, M.D., Denborough, M.A. :
Characterization of the Terminal Cisternae and Longitudinal Tubules of Sarcoplasmic Reticulum from Malignant Hyperpyrexia Susceptible Porcine Skeletal Muscle International Journal of Biochemistry 21:1119-1126, 1989. Pubmed reference: 2583347.
Gallant, E.M., Mickelson, J.R., Roggow, B.D., Donaldson, S.K., Louis, C.F., Rempel, W.E. :
Halothane-Sensitivity Gene and Muscle Contractile Properties in Malignant Hyperthermia American Journal of Physiology 257:C781-C786, 1989. Pubmed reference: 2801926.
Honkavaara, M. :
Influence of Lairage on Blood Composition of Pig and on the Development of PSE Pork Journal of Agricultural Science in Finland 61:425-432, 1989.
Honkavaara, M. :
Influence of Carcass Temperature, Glycogenolysis and Glycolysis 45 Min Postmortem on the Development of PSE Pork Journal of Agricultural Science in Finland 61:433-440, 1989.
Honkavaara, M. :
Influence of Selection Phase, Fasting and Transport on Porcine Stress and on the Development of PSE Pork Journal of Agricultural Science in Finland 61:415-423, 1989.
Jonsson, L., Haggendal, J., Johansson, G., Thorentolling, K., Bjurstrom, S., Carlsten, J. :
Cardiac Manifestation and Blood Catecholamine Levels During Succinylcholine-Induced Stress of Malignant Hyperthermia Sensitive Pigs Journal of Veterinary Medicine Series A-Animal Physiology Pathology and Clinical Veterinary Medicine-Zentralblatt Fur Veterinarmedizin Reihe a 36:772-782, 1989.
Lewis, P.K., Rakes, L.Y., Brown, C.J., Noland, P.R. :
Effect of Exercise and Pre-Slaughter Stress on Pork Muscle Characteristics Meat Science 26:121-129, 1989.
Mickelson, J.R., Gallant, E.M., Rempel, W.E., Johnson, K.M., Litterer, L.A., Jacobson, B.A., Louis, C.F. :
Effects of the Halothane-Sensitivity Gene on Sarcoplasmic Reticulum Function American Journal of Physiology 257:C787-C794, 1989. Pubmed reference: 2801927.
Ohta, T., Endo, M., Nakano, T., Morohoshi, Y., Wanikawa, K., Ohga, A. :
Ca-Induced Ca Release in Malignant Hyperthermia-Susceptible Pig Skeletal Muscle American Journal of Physiology 256:C358-C367, 1989. Pubmed reference: 2919663.
Poltarsky, J. :
Meat Performance and Meat Quality in Pigs with the Malignant Hyperthermia Syndrome Zivocisna Vyroba 34:807-814, 1989.
Reik, T.R. :
Effects of breed and stress susceptibility on production and carcass traits in swine Dissertation Abstracts International, B 49:2433, 1989.
Renou, J.P., Kopp, J., Gatellier, P., Monin, G., Kozakreiss, G. :
NMR Relaxation of Water Protons in Normal and Malignant Hyperthermia-Susceptible Pig Muscle Meat Science 26:101-114, 1989.
Simpson, S.P., Webb, A.J. :
Growth and Carcass Performance of British Landrace Pigs Heterozygous at the Halothane Locus Animal Production 49:503-509, 1989.
Southwood, O.I., Mercer, J.D. :
Efficiency of halothane selection in a commercial British Landrace breeding herd Research and Development in Agriculture 6:37-40, 1989.
Szilagyi, M., Laky, G., Suri, A., Guba, F. :
Activities of Some Serum Enzymes in Halothane Reacted and Non- Reacted Pigs Acta Veterinaria Hungarica 37:117-121, 1989. Pubmed reference: 2626995.
Vogeli, P. :
Position of the Phi and Po2 loci in the Hal linkage group in pigs Genetique, Selection, Evolution 21:119-125, 1989.
Weiskopf, R.B., Eger, E.I., Holmes, M.A., Rampil, I.J., Johnson, B., Brown, J.G., Yasuda, N., Targ, A.G. :
Epinephrine-Induced Premature Ventricular Contractions and Changes in Arterial Blood Pressure and Heart Rate During I-653, Isoflurane, and Halothane Anesthesia in Swine Anesthesiology 70:293-298, 1989. Pubmed reference: 2464293.
1988 Akita, T., Watanabe, S. :
[Relationship between speed of halothane reaction and the activities of serum CPK, LDH and LDH(5) isozyme in the halothane positive pigs] Bulletin of National Institute of Animal Industry, Japan :11-16, 1988.
Bergonzini, E., Fabbri, R., Rosi, M.A., Masoero, G. :
[Blood creatinine, finishing and carcass performance and cured hams of halothane positive and negative pigs] Rivista di Suinicoltura 29:33-37, 1988.
Brenner, K.V. :
[Effect of an alpha- or beta-adrenergic agonist on the creatine kinase activity in blood serum of stress-susceptible and stress-resistant pigs during a catecholamine infusion] Journal of Animal Breeding and Genetics 105:1-10, 1988.
Cepica, S., Hyanek, J., Pazdera, J. :
Statistical test for determination of Hal genotypes of boars by test matings Journal of Animal Breeding and Genetics 105:21-25, 1988.
Davies, W., Harbitz, I., Fries, R., Stranzinger, G., Hauge, J.G. :
Porcine malignant hyperthermia carrier detection and chromosomal assignment using a linked probe Animal Genetics 19:203-212, 1988. Pubmed reference: 3207216.
Erhard, L., Wittman, W., Cwik, S., Schmid, D.O. :
[Studies on the blood group and halothane status of progeny of two German Landrace boars] Bayerisches Landwirtschaftliches Jahrbuch 65:221-230, 1988.
Gahne, B., Juneja, R.K. :
In vivo prediction of meat quality in pigs by genetic markers :113-125, 1988.
Glodek, P. :
[Breeding strategies to overcome the conflict between performance and health in pigs] Tierarztliche Praxis 16:11-15, 1988.
Grashorn, M. :
Comparison of different hypotheses for the inheritance of halothane susceptibility Journal of Animal Breeding and Genetics 105:204-217, 1988.
Heinze, P.H., Mitchell, G. :
Growth, carcase and meat characteristics of stress susceptible and stress resistant South African Landrace gilts South African Journal of Animal Science 18:42-46, 1988.
Hubbard, D.J., Southwood, O.I., Kennedy, B.W. :
Estimation of the halothane gene frequency in Canadian swine using test station records :33 only, 1988.
Jones, S.D.M., Murray, A.C., Sather, A.P., Robertson, W.M. :
Body proportions and carcass composition of pigs with known genotypes for stress susceptibility fasted for different periods of time prior to slaughter Canadian Journal of Animal Science 68:139-149, 1988.
Koliandr, P. :
[Evaluating pigs for stress resistance] Zootekhniya :30-31, 1988.
Makeveev, T., Profirov, Y. :
[Genetic aspects of variation of calcium in blood plasma of pigs] Gentika i Selektsiya 21:332-335, 1988.
Mickelson, J.R., Gallant, E.M., Litterer, L.A., Johnson, K.M., Rempel, W.E., Louis, C.F. :
Abnormal sarcoplasmic reticulum ryanodine receptor in malignant hyperthermia. J Biol Chem 263:9310-5, 1988. Pubmed reference: 3379071.
Nyberg, L., Lundstrom, K., Edfors-Lilja, I., Rundgren, M. :
Effects of transport stress on concentrations of cortisol, corticosteroid-binding globulin and glucocorticoid receptors in pigs with different halothane genotypes Journal of Animal Science 66:1201-1211, 1988. Pubmed reference: 3397347.
Puonti, M., Schulman, A. :
Eradication of halothane gene from Finnish pig population :478 only, 1988.
Reinecke, S., Kalm, E. :
[Associations between halothane reaction, marker genes, activity of creatine kinase and performance traits of Pietrain and German Landrace B pigs] Zuchtungskunde 60:330-344, 1988.
Sellier, P., Mejenes-Quijano, A., Marinova, P., Talmant, A., Jacquet, B., Monin, G. :
Meat quality as influenced by halothane sensitivity and ultimate pH in three porcine breeds Livestock Production Science 18:171-186, 1988.
Southwood, O.I., Simpson, S.P., Curran, M.K., Webb, A.J. :
Frequency of the halothane gene in British Landrace and Large White pigs Animal Production 46:97-102, 1988.
Southwood, O.I., Simpson, S.P., Webb, A.J. :
Reaction to halothane anaesthia among heterozygotes at the halothane locus in British Landrace pigs Genetique, Selection, Evolution 20:357-366, 1988.
Vecchionacce Rojas, H. :
[Pale soft exudative meat. Causes and implications] Boletin de la Sociedad Veterinaria Venezolana de Especialistas en Cerdos 3:54-57, 1988.
Yablanski, T :
[Recombination frequency and gene order in the group of linked loci S-Phi-Hal-H-Pgd in German Landrace pigs] Genetika i Selektsiya 21:413-419, 1988.
Yablanski, T., Zhelyazkov, E. :
[The possibility of practical use of haplotypes of group-linked loci S-Phi-Hal-H-Pgd for the determination of the Hal locus genotypes in pigs] Zhivotnov'dni Nauki 25:70-75, 1988.
Zeveren, A. van, Weghe, A. van de, Bouquet, Y. Varewyck, H. :
The porcine stress linkage group. III. Linkage disequilibria and application of blood marker analysis in selection against stress susceptibility in Belgian Landrace pigs Journal of Animal Breeding and Genetics 105:195-203, 1988.
Zeveren, A. van, Weghe, A. van de, Bouquet, Y., Varewyck, H. :
The porcine stress linkage group. I. The sequence of the linked blood marker loci in Belgian Landrace pigs Journal of Animal Breeding and Genetics 105:177-186, 1988.
Zeveren, A. van, Weghe, A. van de, Bouquet, Y., Varewyck, H. :
The porcine stress linkage group. II. The position of the halothane locus and the accuracy of the halothane test diagnosis in Belgian Landrace pigs Journal of Animal Breeding and Genetics 105:187-194, 1988.
1987 Bader, R. :
Histological findings in skeletal muscles of pigs with different stress susceptibility Journal of Veterinary Medicine, A 34:452-464, 1987.
Barthelemy, G., Darre, R. :
[Electrophoretic variants of blood proteins in domestic and wild pigs: presentation and applications] Revue de Medecine Veterinaire 138:839-851, 1987.
Barton-Gade, P.A. :
Meat and fat quality in boars abd gilts Livestock Production Science 16:187-196, 1987.
Barton-Gade, P.A., Olsen, E.V. :
Experience in measuring the meat quality of stress-susceptible pigs :117-128, 1987.
Baulain, U., Meyer, J.N., Brandt, H., Glodek, P. :
Halothane reaction, blood markers and litter performance in pigs :1266-1267, 1987.
Brinkord, C. :
[Studies on use of the halothane test, viability and carcass quality of pigs of different genetic origins with particular reference to some cell physiological traits of liver and testis microsomes and blood serum] Thesis, Fachbereich Veterinarmedizin, Justus-Liebig-Universitat Giessen, German Federal republic :167 pp., 1987.
Chambers, J., Hall, R.R. :
Porcine malignant hyperthermia (porcine stress syndrome) Compendium on Continuing Education for the Practicing Veterinarian 9:F317-F320, 1987.
Edfors-Lilja, I., Lundstrom, K., Nyberg, L., Rundgren, M. :
Influence of the Hal locus and standardized stress on antibody response and in vitro reactivity of peripheral blood lymphocytes in pigs Veterinary Immunology and Immunopathology 14:157-171, 1987. Pubmed reference: 3564363.
Fesus, L., Palovics, A., Osvath, L., Szollosi, E. :
[Effect of selection on the basis of genetic markers (blood groups and enzymes) on meat quality and stress resistance in pigs. 2. Linkage of the Ha blood group and the PHI and 6-PGD enzyme types with litter size at birth and at 21 days of age] Allattenyesztes es Takarmanyozas 36:433-439, 1987.
Fischer, K. :
The importance of reaction intensity in the halothane test :379-386, 1987.
Ikeda, T., Ando, S., Nakai, H. :
[Comparison of physio-chemical and organoleptic properties of normal and PSE pork for processing purposes] Bulletin of National Institute of Animal Industry, Japan :55-59, 1987.
Jovanovic, S., Gagrcin, N., Nikolic, P. :
[Polymorphism of phosphohexose isomerase (PHI) in different pig breeds] Veterinarski Glasnik 41:912-914, 1987.
Jovanovic, S., Gagricin, M., Loncarevic, A. :
[Results of the halothane test on some pig breeds in Serbia] Veterinarski Glasnik 41:757-761, 1987.
Juneja, R.K., Gahne, B. :
Simultaneous phenotyping of pig plasma alpha-protease inhibitors (P11, PO1A, PO1B, P12) and four other proteins (PO2, TF, CP, HPX) by a simple method of 2D horizontal electrophoresis Animal Genetics 18:197-211, 1987. Pubmed reference: 3662119.
Kolb, E. :
[New biochemical findings regarding the origins of stress susceptibility and of changes in pigs with watery pork (PSE)] Tierzucht 41:557-559, 1987.
Lampo, P. :
[Stress susceptibility in pigs: diagnosis, genetic basis, zootechnical effects and possible solutions by breeding plans. A review] Vlaams Diergeneeskundig Tijdschrift 56:77-88, 1987.
Lengerken, G. von, Schwalbe, M. :
[Efficiency of selection against halothane susceptibility in breeding centres for German Landrace and Schwerfurt pigs] Archiv fur Tierzucht 30:547-555, 1987.
Lundeheim, N. :
[Possibilities of improving the health of pigs by means of breeding. 2] Kungliga Skogs- och Lantbruksakademiens Tidskrift 126:439-446, 1987.
Pinkas, A., Makaveev, T., Aleksandrova, N. :
[Early diagnosis of stress susceptibility and PSE meat in Camborough pigs] Zhivotnov'dni Nauki 24:59-66, 1987.
Poltarsky, J., Bulla, J. :
[The development of malignant hyperthermia syndrome and its relationship with the performance of sows] Zivocisna Vyroba 32:843-850, 1987.
Regal, D.S., Waginger, H., Baumgartner, W. :
[Ultrahistochemical demonstration of enzyme activities to explain metabolic changes in pale, soft exudative pig meat] Journal of Veterinary Medicine, A 34:133-147, 1987.
Sabec, D., Lazar, P., Pokorn, A., Janezic, M., Cerne, I., Pirc, B. :
Fattening and carcass characteristics of pigs susceptible and resistant to halothane Zbornik Biotehniske Fakultete Univerze Edvarda Kardelja v Ljubljani, Veterinarstvo 24:63-68, 1987.
Sellier, P., Cousin, V., Dando, P. :
Effects of halothane sensitivity on male and female reproductive performance in Pietrain lines Annales de Zootechnie 36:249-263, 1987.
Webb, A.J. :
[Genetic selection for the improvement of meat quality and breeding performance] Rivista di Suinicoltura 28:29-36, 1987.
Webb, A.J., Southwood, O.I., Simpson, S.P. :
[The halothane test for improving meat quality] Rivista di Suinicoltura 28:25-32, 1987.
Willeke, H. :
[Ways of breeding resistant sows] Tierzuchter 39:335-336, 1987.
Yablanski, T. :
[Halothane susceptibility and the performance of line Ch Belgian Landrace pigs] Zhivotnov'dni Nauki 24:34-37, 1987.
1986 Babaev, A.A., Kazachok, G.E., Efimov, V.I., Myagkova, V.V. :
[The use of the halothane test in the selection of pigs for stress resistance] :12-20, 1986.
Beckova, R. :
[The frequency of meat quality traits within certain limits in Belgian Landrace and synthetic line 98 pigs] Vedecke Prace Vyzkumneho Ustavu pro Chov Prasat v Kostelci nad Orlici 6:1-23, 1986.
Bleicher, H. :
[Results of the halothane test on Franconian breeding farms] Zuchtwahl und Besamung :69-71, 1986.
Bousset, J., Dumont, B.L. :
[Carcass traits, muscle composition and meat quality in halothane-positive and halothane-negative Poetrain boars] :47-54, 1986.
Cepica, S., Hojny, J., Hradecky, J. :
[The relationship among the S, Phi, H and Pgd loci and the Hal locus in Landrace pigs from a pedigreed herd] Zivocisna Vyroba 31:577-584, 1986.
Cepica, S., Hradecky, J., Hojny, J., Kuryl, J., Grzybowski, G. :
Localization of the Po2 locus in the S, Phi, Hal, H, Po2, Pgd linkage group in pigs Animal Genetics 17:283-286, 1986. Pubmed reference: 2429594.
Cheah, K.S., Cheah, A.M., Waring, J.C. :
Phospholipase A(2) activity, calmodulin, CA(2+) and meat quality in young and adult halothane-sensitive and halothane-insensitive British Landrace pigs Meat Science 17:37-53, 1986.
Cvejn, J. :
[The use of stress suceptibility and biochemical teats of meat in Belgian Landrace and synthetic line 98 pigs] Vedecke Prace Vyzkumneho Ustavu pro Chov Prasat v Kostelci nad Orlici 6:25-47, 1986.
Edfors-Lilja, I. :
[Improved disease resistance in pigs by exploitation of genetic variation in immune defences] Konsulentavdelningens Rapporter, Sveriges Lantbruksuniversitet 82:1-5, 1986.
Ender, K. :
[Relationship between stress tolerance and meat quality in cattle and pigs] Archiv fur Tierzucht 29:373-377, 1986.
Fesus, L., Palovics, A., Osvath, L., Szollosi, E. :
[The effect of selection on marker traits for stress resistance and meat quality (blood groups and enzymes) on meat production in pigs. 1. Relationship of the Ha blood group and phosphohexose isomerase (PHI) with bofy weight, daily gain and percentage of valuable carcass parts] Allattenyesztes es Takarmanyozas 35:461-465, 1986.
Hajkova, J., Cerny, M., Borkovec, L., Lojda, L. :
[Screening for genetic health and the intensification of production of pig meat] Veterinarstvi 36:348-351, 1986.
Hyldgaard-Jensen, J.F. :
Adenosine deaminase and meat quality in pigs - role of an antilipolytic action of adenosine Israeli Journal of Veterinary Medicine 42:278-285, 1986.
Kallweit, E. :
[Methods of improving stress resistance and meat quality by means of breeding] Zuchtungskunde 58:407-415, 1986.
Kalm, E. :
Evaluation and utilisation of breed resources: as sire lines in crossbreeding :35-44, 1986.
Kofer, J., Leitner, B., Golles, J. :
[Evaluation of meat quality in halothane-negative pigs] Fleischwirtschaft 66:1159-1163, 1986.
McDonell, W.N., Seeler, D.C., Basrur, P.K. :
Evaluation of a commercial creatine kinase screening test for malignant hyperthermia (porcine stress syndrome) Canadian Journal of Veterinary Research 50:494-501, 1986. Pubmed reference: 3791075.
Mercer, J.T., Southwood, O.I. :
Selection against halothane reaction in a commercial Landrace nucleus herd :168-171, 1986.
Monin, G., Talmant, A., Laborde, D., Zabari, M., Sellier, P. :
Compositional and enzymatic characteristics of the longissimus dorsi muscle from Large White, halothane-positive and halothane-negative Pietrain and Hampshire pigs Meat Science 16:307-316, 1986.
Nikitchenko, I.N., Gorin, V.V., Yakushik, V.N. :
[Use of the halothane test in the selection of pigs] Sbornik Trudov, Belorusskii Nauchno-Issledovatel'skii Institut Zhivotnovodstva :13-16, 1986.
Robert, S., Dallare, A. :
An exploratory study of behavioural differences between young pigs susceptible and nonsusceptible to stress syndrome Applied Animal Behaviour Science 16:335-343, 1986.
Salomon, F.V., Fiedler, I., Ziegan, J., Heinz, M. :
[Malignant hyperthermia and morphological characteristics of skeletal muscle in swine] Monatshefte fur Veterinarmedizin 41:156-158, 1986.
Simpson, S.P., Webb, A.J., Wilmut, I. :
Performance of British Landrace pigs selected for high and low incidence of halothane sensitivity. 1. Reproduction Animal production 43:485-492, 1986.
Southwood, O.I., Curran, M.K., Simpson, S.P., Webb, A.J. :
Estimated halothane gene frequency in eight British pig breeding companies :2 pp., 1986.
Southwood, O.I., Simpson, S.P., Webb, A.J. :
Incomplete recessive inheritance and maternal effects on halothane sensitivity in British pigs :401-406, 1986.
Troshenkova, L.V. :
[The possibility of using blood groups for the determination of stress resistance in pigs] Sbornik Trudov, Belorusskii Nauchno-Issledovatel'skii Institut Zhivotnovodstva :8-12, 1986.
Webb, A.J., Imlah, P., Carden, A.E. :
Succinylcholine and halothane as a field test for the heterozygote at the halothane locus in pigs Animal Production 42:275-279, 1986.
Webb, A.J., Simpson, S.P. :
Performance of British Landrace pigs selected for high and low incidence of halothane sensitivity. 2. Growth and carcass traits Animal production 43:493-503, 1986.
Willeke, H. :
A note on the effect of the halothane type of sows on lifetime prolificacy and litter parity at culling Livestock Production Science 14:205-210, 1986.
1985 Archibald, A.L., Imlah, P. :
The halothane sensitivity locus and its linkage relationships Animal Blood Groups and Biochemical Genetics 16:253-263, 1985. Pubmed reference: 2421615.
Brunken, H.-G., Meyer, J.-N., Glodek, P. :
Investigations of the halothane linkage group in German Landrace pigs Animal Blood Groups and Biochemical Genetics 16:Suppl. 1, pp. 97-98, 1985.
Carden, A.E., Hill, W.G., Webb, A.J. :
The effects of halothane susceptibility on some economically important traits in pigs. 1. Litter productivity Animal Production 40:351-358, 1985.
Courreau, J.F. :
[Postgraduate refresher article. Halothane sensitivity in swine, a genetic study] Recueil de Medecine Veterinaire 161:385-396, 1985.
Courreau, J.F., Sellier, P., Boulard, J., Breton, T., Goullieux, P., Guerin, G. :
[Blood markers (phosphohexose isomerase and phosphogluconate dehydrogenase) and halothane susceptibility in French Landrace pigs] :95-104, 1985.
Cruz-Bustillo, D., Dieguez, F.J., Andujar, G., Hombre, R. de, Herrera, H. :
[Indications of carcass quality in pigs with normal or potentially PSE carcasses at a slaughterhouse] Ciencia y Tecnica en la Agriclutura, Ganado Porcino 8:67-82, 1985.
Gahne, B., Juneja, R.K. :
Prediction of the halothane (Hal) genotypes of pigs by deducing Hal, Phi, Po2, Pgd haplotypes of parents and offspring: results from a large-scale practice in Swedish breeds Animal Blood Groups and Biochemical Genetics 16:265-283, 1985. Pubmed reference: 3832972.
Glodek, P., Meyer, J.-N., Brunken, H.-G. :
Associations between marker genotypes, halothane reaction, creatine kinase activity and meat quality characters in a sample of German Landrace pigs Animal Blood Groups and Biochemical Genetics 16:319-327, 1985. Pubmed reference: 2421617.
Grashorn, M., Muller, E. :
Relationships between blood groups, isozymes and halothane reaction in pigs from a selection experiment Animal Blood Groups and Biochemical Genetics 16:329-335, 1985. Pubmed reference: 3832975.
Hojny, J., Cepica, S., Hradecky, J. :
Gene order and recombination rates in the linkage group S-Phi-Hal-H-(Po2)-Pgd in pigs Animal Blood Groups and Biochemical Genetics 16:307-318, 1985. Pubmed reference: 3832974.
Honkavaara, M. :
Influence of halothane positive pigs on technological yield of cooked ham :11-13, 1985.
Hradecky, J., Hruban, V., Hojny, J., Pazdera, J., Stanek, R. :
Development of a semi-inbred line of Landrace pigs. I. Breeding performance and immunogenetic characteristics Laboratory Animals 19:279-283, 1985. Pubmed reference: 4068654.
Kadima-Nkashama, M., Bogner, H., Krausslich, H., Schmid, D.O., Sprengel, D., Matzke, P., Blendl, H.M., Gehra, H. :
[Relationships among blood-group markers, stress resistance, fattening performance and carcass characters and quality of German Landrace pigs] Bayerisches Landwirtschaftliches Jahrbuch 62:601-629, 1985.
Kofer, J., Glawischnig, E., Rohrbacher, H. :
[Halothane test programme in Styria] Wiener Tierarztliche Monatsschrift 72:170-173, 1985.
Kovach, G., Horn, P., Lengerken, G. von, Pfeiffer, H. :
[Halothane test in selection for stress tolerance in pigs] Szaktanacsok :13-20, 1985.
Kovach, G., Horn, P., Lengerken, G. von, Pfeiffer, H. :
[Sensitivity to stress in pigs with special regard to creatine kinase test and meat quality] Szaktanacsok :21-26, 1985.
Mal'a, P., Baranova, M., Pleva, J., Belickova, E., Siklenka, P. :
[Evaluating the response to halothane in responding and non-responding pigs in relation to meat quality] Zivocisna Vyroba 30:637-642, 1985.
Matzke, P., Kadima-Nkashama, M., Sprengel, D., Peschke, W. :
[Relationships between blood markers, resistance to stress and meat quality in German Landrace pigs] Berliner und Munchener Tierarztliche Wochenschrift 98:329-332, 1985. Pubmed reference: 4074313.
Michalski, Z., Kamyczek, M. :
[The response of purebred and crossbred pigs to the halothane test] Roczniki Naukowe Zootechniki 12:135-141, 1985.
Monin, G., Sellier, P. :
Pork of low technological quality with a normal rate of muscle pH fall in the immediate post-mortem period: the case of the Hampshire breed Meat Science 13:49-63, 1985.
O'Brien, P.J., Rooney, M.T., Reik, T.R., Thatte, H.S., Rempel, W.E., Addis, P.B., Louis, C.F. :
Porcine malignant hyperthermia susceptibility: erythrocyte osmotic fragility American Journal of Veterinary Research 46:1451-1456, 1985. Pubmed reference: 4026025.
Pavlik, J., Siler, R. :
[The problem of susceptibility to stress in pigs from a synthetic sire line based on Duroc and Belgian Landrace breeds] Sbornik Vysoka Skoly Zemedelske v Praze, Faculta Agronomicka, B (Zivocisna Vyroba) 43:173-186, 1985.
Pavlik, J., Siler, R. :
[Selection on results of halothane tests in pedigree herds] Zivocisna Vyroba 30:779-788, 1985.
Pavlik, J., Siler, R. :
[The frequency of terminal hybrids susceptible to stress factors in pig breeding] Agriculturae Bohemoslovaca 17:137-145, 1985.
Pfutzner, H., Kleibel, A., Fialik, E. :
[PSE muscles. Interpretation of dielectric loss factors] Fleischwirtschaft 65:46-49, 1985.
Poltarsky, J., Bulla, J. :
[Preslaughter stress and meat quality in pigs with different response to halothane] Zivocisna Vyroba 30:807-816, 1985.
Poltarsky, J., Bulla, J. :
[Finishing performance of pigs in relation to their response to halothane] Pol'nohospodarstvo 31:621-627, 1985.
Poltarsky, J., Bulla, J., Palanska, O. :
[Halothane test an an indicator of meat quality in pigs] Pol'nohospodarstvo 31:547-553, 1985.
Schlenker, G., Pohle, M., Wiegand, C., Lengerken, G. von, Arndt, S. :
[Influence of exposure of pigs to stress on the proportion of positive reactions in the halothane test] Monatshefte fur Veterinarmedizin 40:300-304, 1985.
Sellier, P. :
[A new feature in the selection of pigs. Blood typing for Phi and Pgd in French Landraces] Techni-Porc 8:7-14, 1985.
Simpson, S.P., Carden, A.E., Webb, A.J., Wilmut, I. :
Influence of the halothane gene on reproduction in pigs :2 pp., 1985.
Southwood, O.I., Webb, A.J., Carden, A.E. :
Halothane sensitivity of the heterozygote at the halothane locus in British Landrace pigs :2 pp., 1985.
Stankovic, M., Cmiljanic, R., Anastasijevic, V., Zaletel, I., Pusic, M., Drobnjakovic, R. :
[A study of porcine stress syndrome in pigs included in the programmes for the production of pigs for large farms] Stocarstvo 39:349-356, 1985.
Vittmann, M. :
[Meat quality in stress-susceptible pigs] Mezhdunarodnyi Sel'skokhozyaistvennyi Zhurnal :83-86, 1985.
Vogeli, P. :
[Blood-group and enzyme investigations in the pig from 1981 to 1984] Kleinviehzuchter 33:889-897, 1985.
Vogeli, P., Schworer, D., Kuhne, R., Wysshaar, M. :
Trends in economic traits, halothane sensitivity, blood group and enzyme systems of Swiss Landrace and Large White pigs Animal Blood Groups na Biochemical Genetics 16:285-296, 1985.
Webb, A.J., Southwood, O.I., Simpson, S.P. :
The halothane gene in pig breeding :53-65, 1985.
Williams, J.M. :
Causes and effects of porcine stress syndromes :175-179, 1985.
Zaveren, A. van, Weghe, A. van de, Bouquet, Y., Varewyck, H. :
The position of the epistatic S locus in the halothane linkage group in pigs Animal Blood Groups and Biochemical Genetics 16:297-305, 1985. Pubmed reference: 2421616.
1984 Berra, G., Miquet, J.M., Colautti, G., Verges, J.B., Casal, J.J. :
[The halothane test for detecting the susceptibility of pigs to stress, resulting in the production of pale, soft exudative meat] Revista Argentina de Produccion Animal 4:855-860, 1984.
Brandsch, H., Kruger, W. :
[Halothane test and estimation of allele frequencies in pig breeding] Archiv fur Tierzucht 27:331-335, 1984.
Carden, A.E., Webb, A.J. :
The effect of age on halothane susceptibility in pigs Animal Production 38:469-475, 1984.
Cepica, S., Hojny, J., Pazdera, J., Hradecky, J., Kralova, D. :
Determination of genotypes for Hal locus by means of simultaneous halothane testing and typing of linked marker loci Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 101:291-297, 1984.
Cheah, K.S., Cheah, A.M., Crosland, A.R., Casey, J.C. :
Relationship between CA(2+) release, sarcoplasmic Ca(2+), glycolysis and meat quality in halothane-sensitive and halothane-insensitive pigs Meat Science 10:117-130, 1984.
Essen-Gustavsson, B., Lindholm, A. :
Fiber types and metabolic characteristics in muscles of wild boars, normal boars, normal and halothane sensitive Swedish Landrace pigs Comparative Biochemistry and Physiology 78:67-71, 1984. Pubmed reference: 6146439.
Fialik, E., Pfutzner, H., Krause, E. :
[Routine detection of PSE muscle using a rapid electrophysical test] Wiener Tierarztliche Monatsschrift 71:66-69, 1984.
Froystein, T., Gronseth, K., Nostvold, S.O., Standal, N. :
Changes in muscle density in pigs during malignant hyperthermia syndrome measured by computerized tomography Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 101:198-214, 1984.
Hillbrand, F.-W., Glodek, P. :
Halothane sensitivity and semen quality of boars in 3 lines of pigs :2 pp., 1984.
Imlah, P. :
Blood group association with severity and speed of the halothane reaction Animal Blood Groups and Biochemical Genetics 15:275-284, 1984. Pubmed reference: 6524710.
Jeremiah, L.E. :
A note on the influence of inherent muscle quality on cooking losses and palatibility attributes of pork loin chops Canadian Journal of Animal Science 64:773-775, 1984.
Knap, P.W., Grier, J.A. de :
[Prospects for selection against stress susceptibility] Bedrijfsontwikkeling 15:733-736, 1984.
Kobylka, V., Cerny, M., Hajkova, J. :
[Inherited abnormalities and defects in pedigreed herds of pigs in the Czech Republic in 1979-1983] Veterinarstvi 34:351-352, 1984.
Kofer, J., Stur, I., Rohrbacher, H., Pieber, U. :
[Selection measures against stress susceptibility in the Styrian herdbook population of German Yorkshires] Wiener Tierarztliche Monatsschrift 71:324, 326, 1984.
Lengerken, G. von, Huagwitz, T., Schwalbe, M. :
[Relationship between halothane susceptibility and several stress criteria in pigs] Wissenschaftliche Zeitschrift der Karl-Marx-Universitat Leipzig, Mathematisch-Naturwissenschaftliche Reihe 33:293-300, 1984.
Matzke, P., Blendl, H.M., Hollwich, W., Gunter, I., Husslein, E., Buchart, G. :
[Relationships of the halothane reaction with finishing performance, carcass characters and meat quality in pigs] Bayerisches Landwirtschaftliches Jahrbuch 61:904-914, 1984.
McGloughlin, P., Somers, C., Tarrant, P.V., Ahern, C.P. :
Pork quality and erythrocyte fragility :25 only, 1984.
Mitchell, G. :
Porcine stress syndromes Dissertion Abstracts International, B 45:1397 only, 1984.
Monin, G. :
[Genotype and meat quality in pigs] Bulletin Technique, Centre de recherches Zootechniques et Veterinaraires de Theix :9-15, 1984.
Monin, G., Gruand, J., Laborde, D., Sellier, P. :
[The Hampshire effect on meat quality in pigs] :59-64, 1984.
Pavlik, J., Siler, R. :
Possibilities of selection for elimination of undesirable pork meat defects and susceptibility of pigs to stress factors Scientia Agriculturae Bohemoslovaca 16:197-203, 1984.
Pavlik, J., Siler, R. :
[Evaluating different approaches to selection leading to elimination of susceptibility of pigs to stress] Zivocisna Vyroba 29:775-782, 1984.
Pleva, J., Cabadaj, R., Mal'a, P., Turek, P. :
[Prediction of PSE meat in pigs by measuring muscle pH before slaughter, and its correlation with creatine kinase activity] Veterinarni Medicina 29:611-618, 1984.
Pohlann, R., Schemel, D., Lyhs, L. :
[Malignant hyperthermia in halothane-sensitive pigs after exposure to maximum neuromotor stress] Archiv fur Experimentelle Veterinarmedizin 38:302-310, 1984. Pubmed reference: 6487013.
Poltarsky, J., Bulla, J. :
[Halothane anaesthesia as a test of constitution, health condition and reproduction ability of pigs] Pol'hohospodarstvo 30:341-347, 1984.
Poltarsky, J., Bulla, J. :
[Halothane anaesthesia as a test of susceptibility to stress, constitution and poor quality of meat in pigs] Zivocisna Vyroba 29:703-802, 1984.
Poltarsky, J., Bulla, J., Sarvasova, E. :
[The possibility of predicting meat quality in live pigs] Vedecke Prace Vyskumneho Ustavu Zivocisnej Vyroby v Nitre :125-131, 1984.
Roose, P. de, Pauwels, H., Lampo, P., Oyaert, W., Hende, C. van den :
[Halothane test for selecting stress-negative pigs] Deutsche Tierartzliche Wochenschrift 91:198-203, 1984.
Schwerin, M., Nurnberg, G., Lengerken, G. von, Heinecke, K. :
[Investigation of the possible mutagenic effect of the halothane test in pigs - dominant lethal test of male pigs] Archiv fur Tierzucht 27:325-330, 1984.
Schworer, D., Morel, P. :
[Correlation between the halothane reaction and fertility in the pig] Schriften der Schweizerischen Vereinigung fur Tierzucht :33-40, 1984.
Seidler, D., Nowak, B., Bartnicke, E., Huesmann, M. :
[PSE diagnosis on the slaughter line. Pt. 2: Comparison of possible diagnoses with a modified MS-tester and the FOM-instrument on the basis of biochemical and structural meat quality parameters] Fleischwirtschaft 64:1499-1505, 1984.
Seidler, D., Nowak, B., Bartnicke, E., Weismann, M. :
[PSE diagnosis on the slaughter line. Pt. 1: Selected traits during the 1st hour post mortem] Fleischwirtschaft 64:1379-1382, 1385-1387, 1984.
Sellier, P., Monin, G., Houix, Y., Dando, P. :
[Meat quality in 4 pig breeds: relationship with halothane susceptibility and plasma creatine phosphokinase activity] :65-74, 1984.
Siler, R., Pavlik, J. :
[Susceptibility to stress within parental populations used for the production of slaughter pigs] Zivocisna Vyroba 29:783-791, 1984.
Stepanov, V.I., Nikitchenko, I.N., Burov, S.V., Mikhailov, N.V. :
[Prediction of stress resistance in meat pigs] Sel'skokhozyaistvennaya Biologiya :33-35, 1984.
Tetkova, M :
[Meat quality in Belgian Landrace and Duroc pigs, and the relationship of stress susceptibility with meat quality after halothane anaesthesia] Zivocisna Vyroba 29:803-809, 1984.
Tikhonov, V.N., Nikitin, S.V., Gorelov, I.G., Troshina, A.I., Bobovich, V.E., Astakhova, N.M. :
[Mapping of the G and H blood group loci to chromosome 15 of wild and domestic pigs] Genetika, USSR 20:662-671, 1984.
Vogeli, P., Stranzinger, G., Schneebeli, H., Hagger, C., Kunzi, N., Gerwig, C. :
Relationship between the H and A-O blood types, phosphohexose isomerase and 6-phosphogluconate dehydrogenase red cell enzyme systems and halothane sensitivity, and economic traits in a superior and an inferior selection line of Swiss Landrace pigs Journal of Animal Science 59:1440-1450, 1984. Pubmed reference: 6526752.
Webb, A.J., Imlah, P., Carden, A.E. :
Succinylcholine and halothane as a field test for the heterozygote at the halothane locus in pigs :2 pp., 1984.
Wilde, R.O. de :
Comparison of halothane-sensitive and halothane-resistant litter-mate pigs for growth, carcass composition, hormonal status and energy balance Livestock Production Science 11:303-313, 1984.
Willeke, H., Amler, K., Fischer, K. :
[The effect of the halothane genotype of the sow on litter size] Zuchtungskunde 56:20-26, 1984.
Yang, T.S., Hawrysh, Z.J., Price, M.A., Aherne, F.X. :
Identification of PSE in the Longissimus muscle of pigs stunned by captive-bolt Meat Science 10:243-251, 1984.
1983 Arvidsson-Rosen, A. :
[Stress susceptibility in pigs - an inherited defect] Husdjur :32-33, 1983.
Bouix, Y., Sellier, P., Monin, G. :
[Effects of halothane susceptibility on growth and body composition in the pig] :245-254, 1983.
Bulla, J., Poltarsky, J., Majerciak, P. :
[Meat quality in pigs in relation to the halothane test and some biochemical indices of the blood and muscles] Zivocisna Vyroba 28:745-750, 1983.
Carden, A.E., Hill, W.G., Webb, A.J. :
The inheritance of halothane susceptibility in pigs Genetique, Selection, Evolution 15:65-81, 1983.
Gahne, B., Juneja, R.K., Pettersson, H. :
Genotypes at the locus for halothane sensitivity (Hal) in pigs revealed by Hal-linked genetic markers in blood :100-103, 1983.
Guerin, G., Ollivier, L., Sellier, P. :
[The Hal, Phi, Pgd, linkage group in the pig: gene order and estimation of the recombination rate] Genetique, Selection, Evolution 15:55-63, 1983.
Hanset, R., Leroy, P., Michaux, C., Kintaba, K.N. :
The Hal locus and its linkage with the Phi and 6-Pgd loci in the Belgian Pietrain and Landrace breeds :130-131, 1983.
Hanset, R., Leroy, P., Michaux, C., Kintaba, K.N. :
The Hal locus in the Belgian Pietrain pig breed Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 100:123-133, 1983.
Juneja, R.K., Gahne, B., Edfors-Lilja, I., Andresen, E. :
Genetic variation at a pig serum protein locus, Po-2, and its assignment to the Phi, Hal, S, H, Pgd linkage group Animal Blood Groups and Biochemical Genetics 14:27-36, 1983. Pubmed reference: 6614592.
Kallweit, E. :
[Breeding aims to improve pork quality] Hohenheimer Arbeiten, Schriftenreihe der Universitat Hohenheim, Reihe Tierische Produktion :19-28, 1983.
Kleibel, A., Pfutzner, H., Krause, E. :
Measurement of dielectric loss factor, a routine method of recognizing PSE muscle Fleischwirtschaft 63:1183-1185, 1983.
Ljungqvist, L., Hyldgaard-Jensen, J. :
[Serum postalbumin-2 (Po-2) and prealbumin (Pi-1) polymorphism in Danish pig breeds and an investigation of relationships between Po-2 and the Phi-Hal-H linkage group] Arsberetning, Institut for Sterilitetsforskning, Kongelige Veterinaer- og Landbohojskole 26:98-108, 1983.
Lundstrom, K., Lundeheim, N., Gahne, B., Sellei, J., Andren, H., Persson, J. :
Relationship between halothane sensitivity, blood types and production characteristics in Swedish progeny tested pigs Swedish Journal of Agricultural Research 13:167-174, 1983.
Mabry, J.W., Christian, L.L., Kuhlers, D.L., Rasmusen, B.A. :
Prediction of susceptibility to the porcine stress syndrome Journal of Heredity 74:23-26, 1983. Pubmed reference: 6827066.
Monin, G. :
[Effect of production and slaughter conditions on the physical and oganleptic characters of pigmeat] :151-176, 1983.
Oishi, T., Abe, T. :
Studies on blood groups and blood protein polymorphism as genetic markers in pigs :77-78, 1983.
Pazdera, J., Hyanek, J., Hruban, V., Hradecky, J., Gahne, B. :
Changes in the phenotype for halothane sensitivity in pigs Livestock Production Science 10:365-371, 1983.
Pleva, J., Balaz, J., Cabadaj, R. :
[The incidence of PSE meat in different commercial types of pig in Slovakia] Zivocisna Vyroba 28:207-213, 1983.
Reik, T.R., Rempel, W.E., McGrath, C.J., Addis, P.B. :
Further evidence on the inheritance of halothane reaction in pigs Journal of Animal Science 57:826-831, 1983. Pubmed reference: 6643300.
Romanov, Yu. D., Troshenkova, L.V. :
[Methods of determining resistance to stress in pigs] Sbornik Trudov. Belorusskii Nauchno-Issledovatel'skii Institut Zhivotnovodstva 24:7-13, 1983.
Runavot, J.P. :
[The halothane test in the French Landrace] Techni-Porc 6:13-16, 1983.
Schworer, D., Mani, R. :
[Selection for meat quality and stress resistance in AI boars] Mitteilungen des Schweizerischen Verbandes fur kunstliche Besamung und der Schweizerischen Arbeitgemeinschaft fur kunstliche Besamung 21:22-24, 1983.
Seeler, D.C., McDonell, W.N., Basrur, P.K. :
Halothane and halothane/succinylcholine induced malignant hyperthermia (porcine stress syndrome) in a population of Ontario boars Canadian Journal of Comparative Medicine 47:284-290, 1983. Pubmed reference: 6640412.
Siler, R., Pavlik, J. :
[The comparison of genotype and allele frequencies at the HAL locus in pig breeds with different susceptibility] Zivocisna Vyroba 28:361-366, 1983.
Siler, R., Plocek, F., Pavlik, J., Zich, V., Prazak, C. :
[Breeding measures necessary in the introduction of the halothane test and suppression of undesirable defects of pig meat] Zivocisna Vyroba 28:311-315, 1983.
Stankovic, M., Cmiljanic, R., Anastasijevic, V., Pusic, M., Zaletel, I., Josipovic, S. :
Halothane test of different genetic groups of pigs :772-773, 1983.
Stur, I., Muller, S., Grubber, H., Schleger, W. :
[Relationships between porcine stress syndrome and the heterozygosity of marker genes] Zuchtungskunde 55:106-113, 1983.
Tanuska, J. :
[The incidence of quality defects of pork (PSE and DFD) according to pH values] Zivocisna Vyroba 28:699-704, 1983.
Tanuska, J. :
[The incidence of meat quality defects (PSE and DFD) in pigs from the Galanta district] Zivocisna Vyroba 28:291-296, 1983.
Thoren-Tolling, K. :
Serum creatine kinase isoenzyme activities as criterion for stress susceptibility in pigs :461-465, 1983.
Vogeli, P., Gerwig, C., Schneebeli, H. :
The A-O and H blood group systems, some enzyme systems and halothane sensitivity of two divergent lines of Landrace pigs using index selection procedures Livestock Production Science 10:159-169, 1983.
Vogeli, P., Gerwig, C., Schneebeli, H. :
Selection for improved meat quality with the aid of the S bloodgroup alleles in Swiss Landrace pigs :152-153, 1983.
Voloshchik, P., Dmitrieva, N., Yusupov, Kh., Tutukin, V., Kalabina, L., Kosenko, L. :
[Susceptibility to stress in gilts] Svinovodstvo :30 only, 1983.
Voloshchik, P., Dmitrieva, N., Yusupov, Kh., Tutukin, V., Kalyabina, L., Kosenko, L. :
[Susceptibility to stress in boars] Svinovodstvo :32-33, 1983.
Webb, A.J. :
The halothane test for porcine stress syndrome :5-11, 1983.
Webb, A.J. :
Effect of halothane phenotype on the performance of British Landrace pigs :2 pp., 1983.
Wood, J.D. :
Meat quality in lean pigs Pig News and Information 5:199-297, 1983.
1982 Camporesi, A., Santoro, P., Lambertini, L. :
[Halothane reactivity and data on processed hams] Societa Italiana delle Scienze Veterinarie 36:442-443, 1982.
Cepica, S. :
[The possibility of using the halothane test in pig breeding] Nas Chov 42:497-500, 1982.
Cepica, S., Hojny, J., Hradecky, J., Klaudy, J. :
[Halothane sensitivity and associations among the Hal, Phi, A and S loci in Prestice pigs] Zivocisna Vyroba 27:587-593, 1982.
Dallaire, S., Deroth, L. :
Incidence of porcine stress syndrome susceptibility at the St Cyrille record of performance station in Quebec Canadian Veterinary Journal 23:168 only, 1982.
Garcia Martin, M. :
[Problems of stress in intensively managed pigs] Avances en Alimentacion y Mejora Animal 23:521-527, 1982.
Heffron, J.J.A., Mitchell, G., Dreyer, J.H. :
Muscle fibre type, fibre diameter and pH-1 values of m. longissimus dorsi of normal, malignant hyperthermia- and PSE-susceptible pigs British Veterinary Journal 138:45-50, 1982. Pubmed reference: 7059782.
Hoyer, H., Hoyer, I. :
[Stress in fattening pigs and the quality of pale, soft, exudative meat: a consequence of vitamin D deficiency?] Deutsche Tierarztliche Wochenschrift 89:482-483, 1982. Pubmed reference: 6762296.
Hyldgaard-Jensen, J., Jorgensen, P.F., Nielsen, P.B. :
[Possible importance of adenosine deaminase for carcass quality in pigs] Arsberetning, Institut for Sterilitetsforskning, Kongelige Veterinaer- og Landbohojskole 25:42-52, 1982.
Imlah, P. :
Linkage studies between the halothane (Hal), phosphohexose isomerase (Phi) and the S(A-O) and H red blood cell loci of Pietrain/Hampshire and Landrace pigs Animal Blood Groups and Biochemical Genetics 13:245-262, 1982. Pubmed reference: 7171127.
Lengerken, G. von, Bergmann, M. :
[Breeding measures aimed at the improvement of stress resistance and meat quality of pigs] :81-94, 1982.
Lunow, J., Schupbach, O., Schneider, A. :
[Halothane genotypes, corticosteroids and lactate dehydrogenase in the pig] Schweizer Archiv fur Tierheilkunde 124:11-18, 1982. Pubmed reference: 7079715.
Monin, G., Girard, J.-P., Sellier, P., Ollivier, L. :
[Composition of the longissimus dorsi muscle in the Pietrain pig in relation to halothane susceptibility and carcass fat percentage] Sciences des Aliments 2:107-112, 1982.
Monin, G., Girard, J.-P., Sellier, P., Ollivier, L. :
Composition of the longissimus dorsi muscle in the Pietrain pig in relation to halothane susceptibility and carcass fat percentage Sciences des Aliments 2:107-112, 1982.
Nardelli, S., Bracchi, P.G., Maggi, E. :
[Pale, soft exudative pig meat. I. Genetic and endocrine aspects of susceptibility to stress (a review)] Annuali della Facolta di Medicina Veterinaria, Universita di Parma 2:351-369, 1982.
Pecquereau, B., Claustriaux, J.J. :
[Stress susceptibility in two Belgian pigs breeds, the Pietrain and the Belgian Landrace] Revue de l'Agriculture 35:3161-3169, 1982.
Pfutzner, H., Fialik, E. :
A new electrophysical method for rapid detection of exudative porcine muscle Zentralblatt fur Veterinarmedizin, A 29:637-645, 1982.
Santoro, P., Lambertini, L., Camporesi, A. :
[Halothane reactivity and meat quality in pigs] Atti della Societa Italinan delle Scienze Veterinarie 36:439-441, 1982.
Schlenker, G., Lengerken, G. von, Rothe, M., Wiegand, C., Bergmann, V., Schmutzler, K. :
[Results of a production experiment on the use of the halothane test, with particluar reference to individual performance and locomotor strength of boars] Monatshefte fur Veterinarmedizin 37:601-606, 1982.
Schmitten, F. :
[Stress susceptibility and meat quality in pigs] Tierzuchter 34:162-165, 1982.
Schworer, D., Mani, R. :
[Selection for meat quality and stress resistance in AI boars] Mitteilungen des Schweizerischen Verbandes fur kunstliche Besamung und der Schweizerischen Arbeitsgemeinschaft fur kunstliche Besamung 20:167-171, 1982.
Sebranek, J.G. :
Pork quality: a research review World Review of Animal Production 18:3, 5, 7-28, 1982.
Slanec, E. :
[The incidence of quality defects of pork in Czechoslovakia and some measures leading to their elimination] Nas Chov 42:194 only, 1982.
Smith, C. :
Estimates of trends in the halothane gene in pig stocks with selection Zeitschrift fur Tierzuchtzung und Zuchtungsbiologie 99:232-240, 1982.
Touraille, C., Monin, G. :
[Organoleptic characters of pork in relation to halothane sensitivity] :33-36, 1982.
Vogeli, P., Schworer, D. :
[Linkage disequilibrium between susceptibility to the malignant hyperthermia syndrome (MHS, halothane sensitivity) and the phenotypes of the H blood group system and the PHI enzyme system in Swiss Improved Landrace pigs] Zuchtungskunde 54:124-130, 1982.
Vogeli, P., Schworer, D., Haggar, C. :
[The importnace of the halothane test, the H blood-group system and the PHI enzyme system in breeding for meat quality in the Swiss Improved Landrace] Schriften der Schweizerischen Vereinigung fur Tierzucht :18-27, 1982.
Webb, A.J., Carden, A.E., Smith, C., Imlah, P. :
Porcine stress syndrome in pig breeding :588-608, 1982.
1981 Andresen, E., Jensen, P., Bartongade, P. :
The porcine HAL locus - a major locus exhibiting overdominance Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 98:170-175, 1981.
Andresen, E., Jensen, P., Jonsson, P. :
Population studies of Phi, Hal, H haplotype frequencies and linkage disequilibria in Danish Landrace pigs Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 98:45-54, 1981.
Bulla, J., Poltarsky, J. :
[The performance and carcasses of pigs susceptible to the halothane test] Nas Chov 41:464-465, 1981.
Cvejn, J., Lisek, J. :
[The results of halothane anaesthesia in pigs from breeding herds] Vedecke Prace Vyzkumneho Ustavu pro Chov Prasat v Kostelci nad Orlici 5:31-45, 1981.
Kukoyi, E.A., Addis, P.B., McGrath, C.J., Rempel, W.E., Martin, F.B. :
Porcine stress syndrome and postmortem muscle characteristics of two purebreds and three specific terminal crosses Journal of Animal Science 52:278-284, 1981. Pubmed reference: 7275857.
Lampo, C. :
[Stress susceptibility in the Belgian Landrace. The relationship between the halothane test and finishing and carcass charcaters] Revue de l'Agriculture 34:213-220, 1981.
Mabry, J.W., Christian, L.L., Kuhlers, D.L. :
Inheritance of porcine stress syndrome Journal of Heredity 72:429-430, 1981. Pubmed reference: 7334204.
Mitchell, G., Heffron, J.J.A. :
Some muscle and growth characteristics of pigs susceptible to stress British Veterinary Journal 137:374-380, 1981. Pubmed reference: 7284743.
Monin, G., Sellier, P., Ollivier, L., Grouteforgea, R., Girard, J.P. :
Carcass characteristics and meat quality of halothane negative and halothane positive Pietrain pigs Meat Science 5:413-423, 1981.
Schmitten, F., Schepers, K.-H., Wagner, E. :
[Studies on diagnosis of stress susceptibility and its relation to performance characters in pigs. 2. Differences in performance between stress-susceptible and stress-resistant pigs] Zuchtungskunde 53:125-134, 1981.
Schmitten, F., Schepers, K.-H., Wagner, E., Trappmann, W. :
[Studies on the diagnosis of stress susceptibility and its relationship to performance characters in pigs. 1. Presentation of the problem, animals and diagnostic methods] Zuchtungskunde 53:118-124, 1981.
Webb, A.J. :
Age effect on expression of halothane gene in pigs Annual Report of the Animal Breeding Research Organisation :?, 1981.
1980 Bickhardt, K., Richter, L. :
Methodische aspekte des creatin-kinase-test (CK-tests) beim schwein Deutsche Tierarztliche Wochenschrift 87:289-328, 1980. Pubmed reference: 7006984.
Carlson, J.P., Christian, L.L., Kuhlers, D.L., Rasmusen, B.A. :
Influence of the porcine stress syndrome on production and carcass traits Journal of Animal Science 50:21-28, 1980. Pubmed reference: 7364680.
Eikelenboom, G., Minkema, D., Eldik, P. van, Sybesma, W. :
Performance of Dutch Landrace pigs with different genotypes for the halothane - induced malignant hyperthermia syndrome Livestock Production Science 7:317-324, 1980.
Eikelenboom, G., Minkema, D., Eldik, P. van, Sybesma, W. :
Results of halothane testing offspring of Dutch Landrace boars of different halothane phenotypes Livestock Production Science 7:283-289, 1980.
Flewellen, E.H., Nelson, T.E., Bee, D.E. :
Porcine malignant hyperthermia--failure of dantrolene dose response to diagnose susceptibility (halothane effect). Can Anaesth Soc J 27:16-21, 1980. Pubmed reference: 7353186.
Hall, G.M., Lucke, J.N., Lovell, R., Lister, D. :
Porcine malignant hyperthermia. VII: Hepatic metabolism. Br J Anaesth 52:11-7, 1980. Pubmed reference: 6990947.
Lucke, J.N. :
Halothane anaesthesia as a method of indentifying stress susceptible pigs Veterinary Annual 21:140-143, 1980.
MacNeil, F. :
What to do with the 'halothane gene' Pig Farming 28:88-89, 1980.
McGloughlin, P. :
Genetic aspects of pig meat quality Pig News and Information 1:5-9, 1980.
McGloughlin, P., Ahern, C.P., Butler, M., McLoughlin, J.V. :
Halothane induced malignant hyperthermia in Irish pig breeds Livestock Production Science 7:147-154, 1980.
Ollivier, L. :
Genetic determination of muscular hypertrophy in the pig Annales de Genetique et de Selection Animale 12:383-394, 1980.
Poltarsky, J., Bulla, J. :
[Pig breeding and the problem of meat quality] Mezhdunarodnyi Sel'skokhozyaistennyi Zhurnal :69-72, 1980.
Rasmusen, B.A., Reece, C.K., Christian, L.L. :
Halothane sensitivity and linkage of genes for H red blood cell antigens, phosphokexose isomerase (PHI) and 6-phosphogluconate dehydrogenase (6-PGD) variants in pigs Animal Blood Groups and Biochemical Genetics 11:93-107, 1980. Pubmed reference: 7436052.
Schulman, A. :
Exertional myopathy in Finnish Landrace pigs. A survey of the situation and evaluation of different control methods Journal of the Scientific Agricultural Society of Finland 52:505-569, 1980.
Schworer, D. :
[Selection for meat quality and stress resistance in pigs in Switzerland] Schweizerische Landwirtschaftliche Monatshefte 58:230-245, 1980.
Schworer, D., Blum, J., Rebsamen, A. :
Parameters of meat quality and stress resistance of pigs Livestock Production Science 7:337-348, 1980.
Webb, A.J. :
The incidence of halothane sensitivity in British pigs Animal Production 31:101-105, 1980.
Webb, A.J. :
The halothane test: a practical method of eliminating porcine stress syndrome Veterinary Record 106:410-412, 1980. Pubmed reference: 7434505.
1979 Andresen, E. :
Linkage disequilibrium responsible for association between susceptibility to the malignant hyperthermia syndrome (MHS) and PHI types in Danish Landrace pigs Acta Agriculturae Scandinavica 29:369-373, 1979.
Andresen, E. :
Associative additive effects of alleles of the H and PHI loci on the quality of meat from Danish Landrace pigs Acta Agriculturae Scandinavica 29:321-325, 1979.
Bergmann, V. :
Stress myopathies in swine manifestations and pathogenesis Monatshefte fur Veterinarmedizin 34:21-28, 1979.
Campion, D.R., Eikelenboom, G., Cassens, R.G. :
Effect of halothane on isometric contractile properties of muscle from stress susceptible and stress resistant pigs Research in Veterinary Science 27:116-118, 1979. Pubmed reference: 504799.
Eddis, P.B., Rempel, W.E., McGrath, C., Aberle, E.D. :
The use of breed differences to study porcine stress susceptibility Acta Agriculturae Scandinavica 21:312-321, 1979.
Ewan, R.C., Topel, D.G., Ono, K. :
Chemical composition of chops from pale, soft, exudative (PSE) and normal pork loins Journal of Food Science 44:678-680, 1979.
Froystein, T., Schie, K.A., Nostvold, S.O. :
Halothane sensitivity, blood CPK-values and meat quality characteristics in pigs selected for rate of gain and backfat thickness Acta Agriculturae Scandinavica 21:432-440, 1979.
Gerwig, C., Vogeli, P., Schworer, D. :
Halothane sensitivity in a positive and negative selection line Acta Agriculturae Scandinavica 21 Suppl:441-450, 1979.
Guérin, G., Ollivier, L., Sellier, P. :
[The "hitch-hiking" effect of a selected gene and gamete combination (linkage disequilibrium): the example of 2 closely linked loci in the swine, Hal (halothane sensitivity) and PHI (phosphohexose isomerase)]. C R Seances Acad Sci D 289:153-6, 1979. Pubmed reference: 117919.
Harrison, G.G. :
Porcine malignant hyperthermia International Anaesthesiology Clinics 17:25-61, 1979.
Hojny, J., Valenta, M., Cepika, S., Hruban, V., Hradecky, J. :
The relationship between halothane sensitivity and blood group systems in pigs Acta Agriculturae Scandinavica 21 Suppl:463-468, 1979.
Hyldgaard-Jensen, J., Nielsen, P.B., Agergaard, N., Moustgaard, J. :
Blood parameters and gene frequency trends in studies of porcine meat quality Acta Agriculturae Scandinavica 21 Suppl:289-301, 1979.
Imlah, P., Thomson, S.R.M. :
The H blood group locus and meat colour, and using blood groups to predict halothane reactors Acta Agriculturae Scandinavica 21 Suppl:403-410, 1979.
Jensen, P. :
Incidence of halothane susceptibility in the Danish Landrace breed and its association with meat quality Acta Agriculturae Scandinavica 21 Suppl:427-431, 1979.
Jorgensen, P.F. :
Polymorphic systems in blood. Associations with porcine halothane sensitivity and meat quality Acta Agriculturae Scandinavica 21 Suppl:386-395, 1979.
Knitaba, K.N., de Ieteren, G. :
Sensitivity to stress and halothane in the pig Annales de Medecine Veterinaire 123:313-326, 1979.
McGloughlin, P., Ahern, C.P., McLoughlin, J.V. :
Halothane sensitivity and PH testing in Irish Pigs Acta Agriculturae Scandinavica 21 Suppl:451-456, 1979.
McLoughlin, J.V., Somers, C.J., Ahern, C.P., Wilson, P. :
Porcine malignant hyperthermia syndrome: effectiveness of spiperone and dantrolene in prevention and treatment Acta Agriculturae Scandinavica, Supplement 21 :343-348, 1979.
McPhee, C.P., Takken, A., D'Arcy, K.J. :
Genetic variation in meat quality and the incidence of malignant hyperthermia syndrome in Large White and Landrace boars Australian Journal of Agriculture and Animal Husbandry 19:43-47, 1979.
Okumura, F., Crocker, B.D., Denborough, M.A. :
Identification to susceptibility to malignant hyperpyrexia in swine British Journal of Anaesthesia 51:171-176, 1979. Pubmed reference: 435338.
Smith, W.C., Lesser, D. :
An economic assessment of pale soft exudative muscle in the pig carcass Animal Production 28:422 only, 1979.
Thoren-Tolling, K. :
CK isozymes in serum of halothane sensitive and non reacting pigs Acta Veterinaria Scandinavica 20:309-311, 1979. Pubmed reference: 484409.
Watanabe, S., Akita, T., Koishikawa, T., Naito, H.K., Himeno, K. :
Association between halothane reactivity and PHI phenotypes, and its significance for predicting meat quality in Japanese Landrace pigs Japanese Journal of Zootechnical Science 50:574-581, 1979.
Webb, A.J., Jordan, C.H.C. :
The halothane test in genetic improvement programmes: experiments with Pietrain/Hampshire pigs Acta Agriculturae Scandinavica 21:418-426, 1979.
1978 Watanabe, S., Akita, T., Mikami, H., Himeno, K. :
Further evidence for the existence of the (PHI-A, Hal-n) haplotype in the Landrace breed Animal Blood Groups and Biochemical Genetics 9:253-256, 1978. Pubmed reference: 756146.
Webb, A.J., Jordon, C.H.C. :
Halothane sensitivity as a field test for stress susceptibility in the pig Animal Production 26:157-168, 1978.
1977 Anon. :
Porcine stress syndrome : scientist zeroes in on the cause and cure Veterinary Medicine and Small Animal Clinician 72:361-362, 1977. Pubmed reference: 585249.
Lucke, J.N., Hall, G.M., Lister, D. :
Anaesthesia of pigs sensitive to malignant hyperthermia. Vet Rec 100:45-8, 1977. Pubmed reference: 319590.
Minkema, D., Eikelenboom, G., Eldik, P. van :
Inheritance of MHS (malignant hyperthermia susceptibility) in pigs Proceedings of the Third International Conference on Production Diseases in Farm Animals, Wageningen :203-207, 1977.
Smith, C., Bampton, P.R. :
Inheritance of reaction to halothane anaesthesia in pigs Genetical Research 29:287-292, 1977. Pubmed reference: 892446.
1976 Aberle, E.D., Addis, P.B., Rempel, W.E. :
Lactate metabolism by cardiac muscle and liver from Pietrain and Minnesota no 1 pigs and their reciprocal crosses Journal of Animal Science 43:1211-1217, 1976. Pubmed reference: 1002623.
Anderson, I.L., Jones, E.W. :
Recent developments in porcine malignant hyperthermia Proceedings of the Fourth International Pig Veterinary Society Congress, Iowa State University, Ames :T3, 1976.
Eikelenboom, G., Eldik, P. van, Minkema, D., Sybesma, W. :
Control of stress susceptibility and meat quality in pig breeding Proceedings of the Fourth International Pig Veterinary Society Congress, Iowa State University, Ames :T8, 1976.
Elizondo, G., Addis, P.B., Rempel, W.E., Madero, C., Martin, F.B., Anderson, D.B., Murple, D.N. :
Stress response and muscle properties in Pietrain (P) Minnesota no. I (M) and PxM pigs Journal of Animal Science 43:1004-1014, 1976. Pubmed reference: 977504.
Heffron, J.J.A., Mitchell, G. :
Calcium uptake by sarcoplasmic reticulum of muscle of pigs susceptible to malignant hyperthermia Proceedings of the Fourth International Pig Veterinary Society Congress, Iowa State University, Ames :T6 only, 1976.
Marple, D.N., Nachreiner, R.F. :
Thryoxine metabolism in stress susceptible swine Proceedings of the Fourth International Pig Veterinary Society Congress, Iowa State University, Ames :T4 only, 1976.
Nelson, T.E., Anderson, I.L. :
Porcine malignant hyperthermia American Journal of Pathology 84:197-199, 1976. Pubmed reference: 937515.
Rasmusen, B.A., Christian, L.L. :
H blood types in pigs as predictors of stress susceptibility Science 191:947-948, 1976. Pubmed reference: 1251204.
Webb, A.J. :
Pale watery pigmeat A.B.R.O. Report :17-23, 1976.
Williams, C.H., Stubbs, D.H., Shanklin, M.D., Hedrick, H.B. :
Energy metabolism and hemodynamics in fulminant hyperthermia stress syndrome swine Proceedings of the Fourth International Pig Veterinary Society Congress, Iowa State University, Ames :T5, 1976.
1975 Campion, D.R., Topal, D.G. :
A review of the role of swine skeletal muscle in malignant hyperthermia Journal of Animal Science 41:779 only, 1975.
Nelson, T.E., Bedell, D.M., Jones, E.W. :
Porcine malignant hyperthermia: effects of temperature and extracellular calcium concentration on halothane-induced contracture of susceptible skeletal muscle Anesthesiology 42:301-306, 1975. Pubmed reference: 1115384.
Ollivier, L., Sellier, P., Monin, G. :
Déterminisme génétique du syndrome d'hyperthermie maligne chez le porc de Piétrain (Genetic determination of malignant hyperthermia syndrome in the Pietrain pig) Annales de Génétique et de Sélection animale 7:159-166, 1975.
Williams, C.H., Houchins, C., Shanklin, M.D. :
Pigs susceptible to energy metabolism in the fulminant hyperthermia stress syndrome British Medical Journal 3:411-413, 1975. Pubmed reference: 1156789.
1974 Eikelenboom, G., Minkema, D. :
Prediction of pale, soft, exudative muscle with a non-lethal test for halothane-induced porcine malignant hyperthermia syndrome. Tijdschrift voor Diergeneeskunde 99:421-426, 1974.
Nelson, T.E., Jones, E.W., Henrickson, R.L., Falk, S.N., Kerr, D.D. :
Porcine malignant hyperthermia: observations on the occurrence of pale, soft exudative musculature among susceptibile pigs American Journal of Veterinary Research 35:347-350, 1974. Pubmed reference: 4819718.
1973 Anderson, I.L. :
Anaesthesia in the pig. Aust Vet J 49:474-7, 1973. Pubmed reference: 4590195.
Ball, R.A., Annis, C.L., Topel. D.G., Christian, L.L. :
Clinical and laboratory diagnosis of porcine stress syndrome Veterinary Medicine and Small Animal Clinician 68:1156-1159, 1973. Pubmed reference: 4490513.
Brooks, G.A., Cassens, R.G. :
Respiratory functions of mitochondria isolated from stress susceptible and stress resistant pigs Journal of Animal Science 37:688-691, 1973. Pubmed reference: 4742097.
Harrison, G.G., Verburg, C. :
Erythrocyte osmotic fragility in hyperthermia-susceptible swine. Br J Anaesth 45:131-3, 1973. Pubmed reference: 4704063.
Kerr, D.D., Jones, E.W., Nelson, T.E., Gatz, E.E. :
Treatment of malignant hyperthermia in swine. Anesth Analg 52:734-9, 1973. Pubmed reference: 4581069.
Nelson, T.E., Jones, E.W., Bedell, D.M. :
Porcine malignant hyperthermia: a study on the triggering effects of succinylcholine Anesthesia and Analgesia 52:908-911, 1973. Pubmed reference: 4796565.
1972 Hall, L.W., Trim, C.M., Woolf, N. :
Further studies of porcine malignant hyperthermia. Br Med J 2:145-8, 1972. Pubmed reference: 5017306.
Harrison, G.G. :
Pale soft, exudative pork, porcine stress syndrome and malignant hyperthermia - an identity? Journal of the South African Veterinary Association 43:57-63, 1972. Pubmed reference: 4680363.
Jones, E.W., Nelson, T.E., Anderson, I.L., Kerr. D.D., Burnap, T.K. :
Malignant hyperthermia of swine Anesthesiology 36:42-51, 1972. Pubmed reference: 5006985.
Nelson, T.E., Jones, E.W., Venable, J.H., Kerr, D.D. :
Malignant hyperthermia of Poland China swine: studies of a myogenic etiology. Anesthesiology 36:52-56, 1972. Pubmed reference: 5006987.
1971 Berman, M.C., du Toit, P., Kench, J.E. :
Hereditary metabolic myopathy in pigs and its association with malignant hyperpyrexia. Changes in glycolytic intermediates and high-energy phosphate compounds during development of halothane-induced muscle rigor and hyperpyrexia in Landrace pigs South African Medical Journal 45:580-590, 1971.
1970 Allen, W.M., Berrett, S., Harding, J.D.J., Patterson, D.S.P. :
Experimentally induced acute stress syndrome in Pietrain pigs Veterinary Record 87:64-69, 1970. Pubmed reference: 5471576.
Berman, M.C., Harrison, G.G., Bull, A.B., Kench, J.E. :
Changes underlying halothane induced malignant hyperpyrexia in Landrace pigs Nature 225:653 only, 1970. Pubmed reference: 5413377.
1969 Sybesma, W. :
Differences in stress susceptibility in slaughter pigs. Some veterinary aspects. Tijdschrift voor Diergeneeskunde 94:1696-1702, 1969.
Sybesma, W., Eikelenboom, G. :
Malignant hyperpyexia syndrome in pigs Netherlands Journal of Veterinary Science 2:155-160, 1969.
1968 Harrison, G.G., Biebuyck, J.F., Terblanche, J., Dent, D.M., Hickman, R., Saunders, J. :
Hyperpyrexia during anaesthesia British Medical Journal 3:594-595, 1968. Pubmed reference: 5667993.
Topel, D.G., Bicknell, E.J., Preston, K.S., Christian, L.L., Matsushima, C.Y. :
Porcine stress syndrome Modern Veterinary Practice 49:40-60, 1968.
1966 Hall, L.W., Woolf, N., Bradley, J.W.P., Jolly, D.W. :
Unusual reaction to suxamethonium chloride British Medical Journal 2:1305 only, 1966.
1964 Briskey, E.J. :
Etiological status and associated studies of pale, soft, exudative porcine musculature Advances in Food Research 13:89-178, 1964. Pubmed reference: 14283271.

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