OMIA:000716-9615 : Neurofibromatosis, generic in Canis lupus familiaris (dog)

In other species: taurine cattle , teleost fishes

Categories: Neoplasm

Possibly relevant human trait(s) and/or gene(s) (MIM number): 162200 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: The occurrence of tumours at multiple sites of the brachial plexus, intercostal nerves and cardiac nerves; and, to a lesser extent, in retroserosal areas of the thorax and abdomen, in nerves to the skeletal muscles, and in roots and ganglia of spinal nerves.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000716-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2021 Osum, S.H., Watson, A.L., Largaespada, D.A. :
Spontaneous and engineered large animal models of neurofibromatosis type 1. Int J Mol Sci 22:1954, 2021. Pubmed reference: 33669386. DOI: 10.3390/ijms22041954.
2018 Hoon-Hanks, L.L., Frank, C.B., Edmondson, E.F. :
Primary meningeal rhabdomyosarcoma of the spinal cord of a young dog with neuromelanocytosis and multiple cutaneous neurofibromas. J Comp Pathol 165:57-61, 2018. Pubmed reference: 30502797. DOI: 10.1016/j.jcpa.2018.09.008.

Edit History

  • Created by Imke Tammen2 on 12 Apr 2021
  • Changed by Imke Tammen2 on 16 Oct 2023