OMIA 000809-9615 : Polycythemia in Canis lupus familiaris
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|JAK2||Janus kinase 2||Canis lupus familiaris||1||NC_051805.1 (93940875..93989640)||JAK2||Homologene, Ensembl, NCBI gene|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Polycythemia||JAK2||complex rearrangement||1||c.[1849G>T;1852T>C;1853G>T]||p.(V617_C618delinsFL)||a three-base change in codons 617 and 618 of JAK2 giving rise to V617F and C618L||2011||21320566|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2011||Beurlet, S., Krief, P., Sansonetti, A., Briend-Marchal, A., Kiladjian, JJ., Padua, RA., Chomienne, C., Cassinat, B. :|
|Identification of JAK2 mutations in canine primary polycythemia. Exp Hematol 39:542-5, 2011. Pubmed reference: 21320566. DOI: 10.1016/j.exphem.2011.02.003.|
|1998||Faissler, D., Griotwenk, M.E., Fatzer, R., Vontscharner, C., Aberlethiemann, B., Jaggy, A. :|
|Seizures due to polycythemia - review of literature and case report [Review] [German] Schweizer Archiv fur Tierheilkunde 140:101-109, 1998. Pubmed reference: 9528346.|
|1997||Vanvonderen, I.K., Meyer, H.P., Kraus, J.S., Kooistra, H.S. :|
|Polyuria and polydipsia and disturbed vasopressin release in 2 dogs with secondary polycythemia Journal of Veterinary Internal Medicine 11:300-303, 1997. Pubmed reference: 9348498.|
|1959||Donovan, E.F., Loeb, W.F. :|
|Polycythemia rubra vera in the dog Journal of the American Veterinary Medical Association 134:36-37, 1959. Pubmed reference: 13610760.|
- Created by Frank Nicholas on 03 Jul 2011
- Changed by Frank Nicholas on 28 Sep 2011
- Changed by Frank Nicholas on 12 Dec 2011
- Changed by Frank Nicholas on 28 Mar 2017