OMIA:000874-30521 : Vertebrae, quantitative variation in Bos grunniens (domestic yak)
Categories: Skeleton phene (incl. short stature & teeth)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: no
Cross-species summary: This phene was originally named 'Rib and vertebral number' in OMIA
Species-specific description: Wang et al. (2020): "a sub-population of yak termed as the Jinchuan yak has been identified with over half its members own a thoracolumbar vertebral formula of T15L5 instead of the natural T14L5 arrangement. The novel T15L5 positioning is a preferred genetic trait leading to enhanced meat and milk production."
Mapping: Wang et al. (2020) "investigated the genetic background of the Jinchuan yak through resequencing fifteen individuals, comprising five T15L5 individuals and ten T14L5 individuals ... Three hundred and thirty candidate markers were identified as associated with the additional thoracic vertebrae and target sequencing was used to validate seven carefully selected markers in an additional 51 Jinchuan yaks. ... Two genes, PPP2R2B and TBLR1, were found to harbour the most candidate markers associated with the trait and likely contribute to the unique somitic number and identity according to their reported roles in the mechanism of somitogenesis."
Cite this entry
|2020||Wang, Y., Cai, H., Luo, X., Ai, Y., Jiang, M., Wen, Y. :|
|Insight into unique somitogenesis of yak (Bos grunniens) with one additional thoracic vertebra. BMC Genomics 21:201, 2020. Pubmed reference: 32131721 . DOI: 10.1186/s12864-020-6598-9.|
- Created by Imke Tammen2 on 27 Sep 2021