OMIA 000874-9940 : Vertebrae, quantitative variation in Ovis aries |
Li et al. (2021) "performed high-throughput genome resequencing on multi-lumbar vertebrae (n = 18) and normal (n = 11) Duolang sheep ... . We found that the most significantly selective region were located in the 49.68-49.74 MB of chromosome 4 by selective-sweep analysis. We annotated this region and found that it contains SFRP4 which is known to regulate bone development. We further used the PCR-SSCP technology to detect the single nucleotide polymorphism (SNP) of the putative candidate SFRP4 and found that the two SNPs (rs600370085:C > T and rs415133338: A > G) of this gene were significantly associated with the multi-lumbar vertebrae of Duolang sheep."
Breeds: Duolang, Han, small-tailed, Hu, Sunite. Associated gene:Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
---|---|---|---|---|---|---|
SYNDIG1L | synapse differentiation inducing 1-like | Ovis aries | 7 | NC_056060.1 (83851144..83794408) | SYNDIG1L | Homologene, Ensembl, NCBI gene |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 | Li, C., Liu, K., Dai, J., Li, X., Liu, X., Ni, W., Li, H., Wang, D., Qiao, J., Wang, Y., Cui, Y., Xia, X., Hu, S. : | |
Whole-genome resequencing to investigate the determinants of the multi-lumbar vertebrae trait in sheep. Gene 809:146020, 2021. Pubmed reference: 34656743. DOI: 10.1016/j.gene.2021.146020. | ||
Zhang, D., Zhang, X., Li, F., Liu, T., Hu, Z., Gao, N., Yuan, L., Li, X., Zhao, Y., Zhao, L., Zhang, Y., Xu, D., Song, Q., Cheng, J., Wang, W. : | ||
Whole-genome resequencing identified candidate genes associated with the number of ribs in Hu sheep. Genomics 113:2077-2084, 2021. Pubmed reference: 33965549. DOI: 10.1016/j.ygeno.2021.05.004. | ||
Zhong, Y.J., Yang, Y., Wang, X.Y., Di, R., Chu, M.X., Liu, Q.Y. : | ||
Expression analysis and single-nucleotide polymorphisms of SYNDIG1L and UNC13C genes associated with thoracic vertebral numbers in sheep (Ovis aries). Archives Animal Breeding 64:131-138, 2021. Pubmed reference: 34084911. DOI: doi: 10.5194/aab-64-131-2021. | ||
2020 | Zhao, F., Deng, T., Shi, L., Wang, W., Zhang, Q., Du, L., Wang, L. : | |
Genomic scan for selection signature reveals fat deposition in Chinese indigenous sheep with extreme tail types. Animals (Basel) 10:773, 2020. Pubmed reference: 32365604. DOI: 10.3390/ani10050773. | ||
2012 | Donaldson, C.L., Lambe, N.R., Maltin, C.A., Knott, S., Bunger, L. : | |
Between and within breed variations of spine characteristics in sheep. J Anim Sci :, 2012. Pubmed reference: 23243168. DOI: 10.2527/jas.2012-5456. |
Edit History
- Created by Imke Tammen2 on 17 Jun 2021
- Changed by Imke Tammen2 on 17 Jun 2021
- Changed by Imke Tammen2 on 03 Nov 2021