OMIA 001202-9031 : Scleroderma in Gallus gallus

Possibly relevant human trait(s) and/or gene(s) (MIM number): 181750

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific name: Also known as Systemic sclerosis. This disorder is characteristic of University of Davis (UCD) lines 200 and 206

Species-specific symbol: SSc

Mapping: Ek et al. (2012) conducted a genome scan on the the backcross generation from a cross between the UCD-200 line and red jungle fowl. QTL were identified on chromosomes GGA2, GGA12, and GGA14.

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2016 Cipriani, P., Di Benedetto, P., Dietrich, H., Ruscitti, P., Liakouli, V., Carubbi, F., Pantano, I., Berardicurti, O., Sgonc, R., Giacomelli, R. :
Searching for a good model for systemic sclerosis: the molecular profile and vascular changes occurring in UCD-200 chickens strongly resemble the early phase of human systemic sclerosis. Arch Med Sci 12:828-43, 2016. Pubmed reference: 27478465. DOI: 10.5114/aoms.2016.60970.
2012 Ek, W., Sahlqvist, A.S., Crooks, L., Sgonc, R., Dietrich, H., Wick, G., Ekwall, O., Andersson, L., Carlborg, Ö., Kämpe, O., Kerje, S. :
Mapping QTL affecting a systemic sclerosis-like disorder in a cross between UCD-200 and red jungle fowl chickens. Dev Comp Immunol 38:352-9, 2012. Pubmed reference: 22796227. DOI: 10.1016/j.dci.2012.06.006.
2010 Beyer, C., Schett, G., Distler, O., Distler, J.H. :
Animal models of systemic sclerosis: prospects and limitations. Arthritis Rheum 62:2831-44, 2010. Pubmed reference: 20617524. DOI: 10.1002/art.27647.
2006 Wick, G., Andersson, L., Hala, K., Gershwin, M.E., Selmi, C., Erf, G.F., Lamont, S.J., Sgonc, R. :
Avian models with spontaneous autoimmune diseases. Adv Immunol 92:71-117, 2006. Pubmed reference: 17145302. DOI: 10.1016/S0065-2776(06)92002-1.
2002 Zhang, Y., Gilliam, A.C. :
Animal models for scleroderma: an update. Curr Rheumatol Rep 4:150-62, 2002. Pubmed reference: 11890881.
1996 Dietrich, H.M., Oliveiradossantos, A.J., Hala, K., Wick, G. :
Skin allograft survival in chicken strains with spontaneous autoimmune diseases Poultry Science 75:285-293, 1996. Pubmed reference: 8778718.
1995 Sgonc, R., Dietrich, H., Gershwin, M.E., Colombatti, A., Wick, G. :
Genomic analysis of collagen and endogenous virus loci in the UCD-200 and 206 lines of chickens, animal models for scleroderma Journal of Autoimmunity 8:763-770, 1995. Pubmed reference: 8579730.
1993 Gruschwitz, M.S., Shoenfeld, Y., Krupp, M., Gershwin, M.E., Penner, E., Brezinschek, H.P., Wick, G. :
Antinuclear Antibody Profile in UCD Line 200 Chickens - A Model for Progressive Systemic Sclerosis International Archives of Allergy and Immunology 100:307-313, 1993. Pubmed reference: 8386962.
1990 Abplanalp, H., Gershwin, M.E., Johnston, E., Reid, J. :
Genetic control of avian scleroderma. Immunogenetics 31:291-5, 1990. Pubmed reference: 2370076.
1981 Gershwin, M.E., Abplanalp, H., Castles, J.J., Ikeda, R.M., van der Water, J., Eklund, J., Haynes, D. :
Characterization of a spontaneous disease of white leghorn chickens resembling progressive systemic sclerosis (scleroderma). J Exp Med 153:1640-59, 1981. Pubmed reference: 7252423.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 05 Jan 2013