OMIA 001206-9796 : Laryngeal paralysis, generic in Equus caballus

In other species: dog , cattle

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific name: Recurrent laryngeal neuropathy. Also known as Laryngeal hemiplegia

Species-specific symbol: RLN


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2018 Brooks, S.A., Stick, J., Braman, A., Palermo, K., Robinson, N.E., Ainsworth, D.M. :
Identification of loci affecting sexually dimorphic patterns for height and recurrent laryngeal neuropathy risk in American Belgian Draft Horses. Physiol Genomics 50:1051-1058, 2018. Pubmed reference: 30265593. DOI: 10.1152/physiolgenomics.00068.2018.
Cook, W.R. :
Fifty years of recurring struggles with recurrent laryngeal neuropathy. Equine Vet J :, 2018. Pubmed reference: 30030931. DOI: 10.1111/evj.12981.
Parente, E.J. :
Fifty years of recurring struggles with recurrent laryngeal neuropathy. Equine Vet J 50:155-158, 2018. Pubmed reference: 28976020. DOI: 10.1111/evj.12763.
2015 Gerber, V., Tessier, C., Marti, E. :
Genetics of upper and lower airway diseases in the horse. Equine Vet J 47:390-7, 2015. Pubmed reference: 24773614. DOI: 10.1111/evj.12289.
2014 Boyko, A.R., Brooks, S.A., Behan-Braman, A., Castelhano, M., Corey, E., Oliveira, K.C., Swinburne, J.E., Todhunter, R.J., Zhang, Z., Ainsworth, D.M., Robinson, N.E. :
Genomic analysis establishes correlation between growth and laryngeal neuropathy in Thoroughbreds. BMC Genomics 15:259, 2014. Pubmed reference: 24707981. DOI: 10.1186/1471-2164-15-259.
2013 Dupuis, M.C., Zhang, Z., Durkin, K., Charlier, C., Lekeux, P., Georges, M. :
Detection of copy number variants in the horse genome and examination of their association with recurrent laryngeal neuropathy. Anim Genet 44:206-8, 2013. Pubmed reference: 22582820. DOI: 10.1111/j.1365-2052.2012.02373.x.
2011 Dupuis, M.C., Zhang, Z., Druet, T., Denoix, J.M., Charlier, C., Lekeux, P., Georges, M. :
Results of a haplotype-based GWAS for recurrent laryngeal neuropathy in the horse. Mamm Genome 22:613-20, 2011. Pubmed reference: 21698472. DOI: 10.1007/s00335-011-9337-3.
2009 Dixon, PM., Hahn, CN., Barakzai, SZ. :
Recurrent laryngeal neuropathy (RLN) research: where are we and to where are we heading? Equine Vet J 41:324-7, 2009. Pubmed reference: 19562891.
2007 Studer, S., Gerber, V., Straub, R., Brehm, W., Gaillard, C., Lüth, A., Burger, D. :
[Prevalence of hereditary diseases in three-year-old Swiss Warmblood horses]. Schweiz Arch Tierheilkd 149:161-71, 2007. Pubmed reference: 17461391.
Studer, S., Gerber, V., Straub, R., Brehm, W., Gaillard, C., Lüth, A., Burger, D. :
Erhebung der Prävalenz von Erbkrankheiten bei dreijährigen Schweizer Warmblutpferden [Prevalence of hereditary diseases in three-year-old Swiss Warmblood horses] Schweiz Arch Tierheilkd 149:161-171, 2007.
2001 Dixon, P.M., McGorum, B.C., Railton, D.I., Hawe, C., Tremaine, W.H., Pickles, K., McCann, J. :
Laryngeal paralysis: a study of 375 cases in a mixed-breed population of horses Equine Veterinary Journal 33:452-458, 2001. Pubmed reference: 11558739.
1997 Christley, R.M., Hodgson, D.R., Evans, D.L., Rose, R.J. :
Cardiorespiratory responses to exercise in horses with different grades of idiopathic laryngeal hemiplegia Equine Veterinary Journal 29:6-10, 1997. Pubmed reference: 9031857.
1996 Kantas, K. :
Etiology and pathogenesis of equine laryngeal hemiplegia - literature review [Hungarian] Magyar Allatorvosok Lapja 51:464-466, 1996.
Tetens, J., Derksen, F.J., Stick, J.A., Lloyd, J.W., Robinson, N.E. :
Efficacy of prosthetic laryngoplasty with and without bilateral ventriculocordectomy as treatments for laryngeal hemiplegia in horses American Journal of Veterinary Research 57:1668-1673, 1996. Pubmed reference: 8915450.
1995 Dalin, G. :
Control of genetically determined diseases and defects in Swedish horse breeding Equine Veterinary Journal 27:411-415, 1995.
Deegen, E., Ohnesorge, B., Miesner, K., Brandt, I. :
Hemiplegia laryngis sinistra - an hereditary disease in horses [summary] Equine Veterinary Journal 27:412-413, 1995.
1993 Beard, W.L., Hayes, H.M. :
Risk Factors for Laryngeal Hemiplegia in the Horse Preventive Veterinary Medicine 17:57-63, 1993.
Lopezplana, C., Sautet, J.Y., Ruberte, J. :
Muscular Pathology in Equine Laryngeal Neuropathy Equine Veterinary Journal 25:510-513, 1993. Pubmed reference: 8275997.
1989 Gerber, H. :
The genetic basis of some equine diseases Equine Veterinary Journal 21:244-248, 1989. Pubmed reference: 2670541.
Poncet, P.A., Montavon, S., Gaillard, C., Barrelet, F., Straub, R., Gerber, H. :
A preliminary report on the possible genetic basis of laryngeal hemiplegia Equine Veterinary Journal 21:137-138, 1989. Pubmed reference: 2707232.
1987 Cahill, J.I., Goulden, B.E. :
The pathogenesis of equine laryngeal hemiplegia New Zealand Veterinary Journal 35:82-90, 1987.
1941 Runciman, B. :
Roaring and whistling in thoroughbred horses Veterinary Record 53:37-38, 1941.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Carrie Finno on 11 Dec 2013