OMIA:001272-9615 : Comedo syndrome in Canis lupus familiaris

Categories: Integument (skin) phene

Possibly relevant human trait(s) and/or gene(s) (MIM number): 120450 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: A comedo (plural comedones) is a plug of keratin and sebum within the dilated orifice of a hair follicle. It frequently contains bacteria.

Species-specific name: Schnauzer comedo syndrome

Species-specific description: Numerous comedones form in the dorsal skin. Schnauzers are particularly predisposed to this disorder.

Breeds: Mexican Hairless Dog (Xoloitzcuintli), Schnauzer.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1997 Hannigan, M.M. :
A refractory case of Schnauzer comedo syndrome Canadian Veterinary Journal - Revue Veterinaire Canadienne 38:238-239, 1997.
1996 Kimura, T., Doi, K. :
Spontaneous comedones on the skin of hairless descendants of mexican hairless dogs Jikken Dobutsu. Experimental Animals 45:377-384, 1996.
Schwartzman, R.M., Kligman, A.M., Duclos, D.D. :
The Mexican hairless dog as a model for assessing the comedolytic and morphogenic activity of retinoids British Journal of Dermatology 134:64-70, 1996. Pubmed reference: 8745888 .

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 23 Oct 2022