OMIA:001416-9614 : Coat colour, dominant black in Canis latrans (coyote)

In other species: gray wolf , dog , water buffalo

Categories: Pigmentation phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 606611 (gene)

Single-gene trait/disorder: yes

Mode of inheritance: Autosomal

Disease-related: no

Key variant known: yes

Year key variant first reported: 2009

Cross-species summary: Also known as the K locus

Molecular basis: Anderson et a. (2009) showed that the 3bp deletion of the CBD103 gene that causes dominant black in dogs, exists also in the orthologous gene in wolves and coyotes, and is strongly associated with black coat colour in both these species.

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
CBD103 Canis latrans - no genomic information (-..-) CBD103 Ensembl

Variants

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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.

Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.

OMIA Variant ID Breed(s) Variant Phenotype Gene Allele Type of Variant Source of Genetic Variant Reference Sequence Chr. g. or m. c. or n. p. Verbal Description EVA ID Year Published PubMed ID(s) Acknowledgements
520 Coat colour, dominant black CBD103 deletion, small (<=20) Naturally occurring variant 3bp deletion of the CBD103 gene 2009 19197024

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2012). OMIA:001416-9614: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

Reference

2009 Anderson, TM., Vonholdt, BM., Candille, SI., Musiani, M., Greco, C., Stahler, DR., Smith, DW., Padhukasahasram, B., Randi, E., Leonard, JA., Bustamante, CD., Ostrander, EA., Tang, H., Wayne, RK., Barsh, GS. :
Molecular and evolutionary history of melanism in North American gray wolves. Science 323:1339-43, 2009. Pubmed reference: 19197024. DOI: 10.1126/science.1165448.

Edit History


  • Created by Frank Nicholas on 12 Oct 2011
  • Changed by Frank Nicholas on 12 Oct 2011
  • Changed by Frank Nicholas on 12 Dec 2011
  • Changed by Frank Nicholas on 21 Mar 2012