OMIA 001525-9615 : Leukocyte adhesion deficiency, type III in Canis lupus familiaris
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|FERMT3||fermitin family member 3||Canis lupus familiaris||18||NC_051822.1 (53896895..53879047)||FERMT3||Homologene, Ensembl, NCBI gene|
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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
|OMIA Variant ID||Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Source of Genetic Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Inferred EVA rsID||Year Published||PubMed ID(s)||Acknowledgements|
|576||German Shepherd Dog||Leukocyte adhesion deficiency, type III||FERMT3||insertion, small (<=20)||Naturally occurring variant||CanFam3.1||18||g.52835932_52835933insGGCAGCCGTCTT||c.1349_1350insAAGACGGCTGCC||p.(L450_A451insRRLP)||XM_038425194.1; XP_038281122.1; 12-base pair insertion||2010||20126836|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2014||Hugo, T.B., Heading, K.L. :|
|Leucocyte adhesion deficiency III in a mixed-breed dog. Aust Vet J 92:299-302, 2014. Pubmed reference: 24954630. DOI: 10.1111/avj.12206.|
|2010||Boudreaux, MK., Wardrop, KJ., Kiklevich, V., Felsburg, P., Snekvik, K. :|
|A mutation in the canine Kindlin-3 gene associated with increased bleeding risk and susceptibility to infections. Thromb Haemost 103:475-7, 2010. Pubmed reference: 20126836. DOI: 10.1160/TH09-09-0571.|
- Created by Frank Nicholas on 03 Nov 2010
- Changed by Martha MaloneyHuss on 18 Aug 2011
- Changed by Frank Nicholas on 26 Sep 2011
- Changed by Frank Nicholas on 28 Sep 2011
- Changed by Frank Nicholas on 12 Dec 2011
- Changed by Frank Nicholas on 17 Jun 2013
- Changed by Frank Nicholas on 11 Apr 2014