OMIA 001617-9685 : Sweet taste, lack of in Felis catus
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|TAS1R2||taste receptor, type 1, member 2 pseudogene||Felis catus||-||no genomic information (-..-)||TAS1R2||Homologene, Ensembl, NCBI gene|
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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
|OMIA Variant ID||Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Source of Genetic Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Inferred EVA rsID||Year Published||PubMed ID(s)||Acknowledgements|
|650||Sweet taste, lack of||TAS1R2||deletion, gross (>20)||Naturally occurring variant||Felis_catus_9.0||C1||Felis_catus_9.0||the TAS1R2 gene in cats, tigers and cheetahs has "a 247-base pair microdeletion in exon 3 and stop codons in exons 4 and 6 ... cat Tas1r2 is an unexpressed pseudogene"||2005||16103917|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2006||Li, X., Li, W., Wang, H., Bayley, D.L., Cao, J., Reed, D.R., Bachmanov, A.A., Huang, L., Legrand-Defretin, V., Beauchamp, G.K., Brand, J.G. :|
|Cats lack a sweet taste receptor. J Nutr 136:1932S-1934S, 2006. Pubmed reference: 16772462.|
|2005||Li, X., Li, W., Wang, H., Cao, J., Maehashi, K., Huang, L., Bachmanov, A.A., Reed, D.R., Legrand-Defretin, V., Beauchamp, G.K., Brand, J.G. :|
|Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar. PLoS Genet 1:27-35, 2005. Pubmed reference: 16103917. DOI: 10.1371/journal.pgen.0010003.|
|1951||Frings, H. :|
|Sweet taste in the cat and the taste-spectrum. Experientia 7:424-6, 1951. Pubmed reference: 14936998.|
- Created by Frank Nicholas on 04 Oct 2011
- Changed by Frank Nicholas on 04 Oct 2011
- Changed by Frank Nicholas on 07 Oct 2011
- Changed by Frank Nicholas on 09 Dec 2011
- Changed by Frank Nicholas on 03 Dec 2012