OMIA:001888-9615 : Muscular dystrophy, Becker type in Canis lupus familiaris

In other species: pig , domestic cat

Categories: Muscle phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 300376 (trait) , 300377 (gene)

Links to MONDO diseases:

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Variants in the DMD gene may give rise to phenotypes with different severity. True null alleles cause the more severe Duchenne muscular dystrophy (OMIA:001081), while alleles with partial remaining protein function give rise to the milder Becker muscular dystrophy.

Reference

2013 Baroncelli, A.B., Abellonio, F., Pagano, T.B., Esposito, I., Peirone, B., Papparella, S., Paciello, O. :
Muscular Dystrophy in a Dog Resembling Human Becker Muscular Dystrophy. J Comp Pathol :, 2013. Pubmed reference: 24529507 . DOI: 10.1016/j.jcpa.2013.12.006.

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  • Created by Frank Nicholas on 26 Mar 2014