OMIA:001888-9615 : Muscular dystrophy, Becker type in Canis lupus familiaris (dog) |
In other species: domestic cat , pig
Categories: Muscle phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 300376 (trait) , 300377 (gene)
Links to MONDO diseases:
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Variants in the DMD gene may give rise to phenotypes with different severity. True null alleles cause the more severe Duchenne muscular dystrophy (OMIA:001081), while alleles with partial remaining protein function give rise to the milder Becker muscular dystrophy.
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2014). OMIA:001888-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 2013 | Baroncelli, A.B., Abellonio, F., Pagano, T.B., Esposito, I., Peirone, B., Papparella, S., Paciello, O. : |
| Muscular Dystrophy in a Dog Resembling Human Becker Muscular Dystrophy. J Comp Pathol , 2013. Pubmed reference: 24529507. DOI: 10.1016/j.jcpa.2013.12.006. |
Edit History
- Created by Frank Nicholas on 26 Mar 2014