OMIA:001905-9940 : Johne's disease, resistance/susceptibility to in Ovis aries (sheep)

In other species: taurine cattle , indicine cattle (zebu) , goat

Categories: Immune system phene

Mendelian trait/disorder: unknown

Considered a defect: no

Cross-species summary: Johne's disease is also called paratuberculosis

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2021). OMIA:001905-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Usai, M.G., Casu, S., Sechi, T., Salaris, S.L., Miari, S., Mulas, G., Cancedda, M.G., Ligios, C., Carta, A. :
Advances in understanding the genetic architecture of antibody response to paratuberculosis in sheep by heritability estimate and LDLA mapping analyses and investigation of candidate regions using sequence-based data. Genet Sel Evol 56:5, 2024. Pubmed reference: 38200416. DOI: 10.1186/s12711-023-00873-4.
2021 Kravitz, A., Pelzer, K., Sriranganathan, N. :
The paratuberculosis paradigm examined: A review of host genetic resistance and innate immune fitness in Mycobacterium avium subsp. paratuberculosis infection. Front Vet Sci 8:721706, 2021. Pubmed reference: 34485444. DOI: 10.3389/fvets.2021.721706.
Yaman, Y., Aymaz, R., Keleş, M., Bay, V., Ün, C., Heaton, M.P. :
Association of TLR2 haplotypes encoding Q650 with reduced susceptibility to ovine Johne's disease in Turkish sheep. Sci Rep 11:7088, 2021. Pubmed reference: 33782507. DOI: 10.1038/s41598-021-86605-4.
Yaman, Y., Aymaz, R., Keleş, M., Bay, V., Hatipoğlu, E., Kaptan, C., Başkurt, A., Yilmaz, O., Heaton, M.P. :
Evaluation of CD109, PCP4 and SEMA3D genes for their association with ovine Johne's disease in Turkish sheep. Anim Biotechnol 32:519-525, 2021. Pubmed reference: 33612073. DOI: 10.1080/10495398.2021.1887880.
2016 Moioli, B. et al. :
Genomic scan for identifying candidate genes for paratuberculosis resistance in sheep. Animal Production Science 56:1046-1055, 2016. DOI: 10.1071/AN14826.
Nicol, L., Gossner, A., Watkins, C., Chianini, F., Dalziel, R., Hopkins, J. :
Variations in IL-23 and IL-25 receptor gene structure, sequence and expression associated with the two disease forms of sheep paratuberculosis. Vet Res 47:27, 2016. Pubmed reference: 26861902. DOI: 10.1186/s13567-016-0314-4.
2015 Bishop, S.C. :
Genetic resistance to infections in sheep. Vet Microbiol 181:2-7, 2015. Pubmed reference: 26260859. DOI: 10.1016/j.vetmic.2015.07.013.
2013 Vir Singh, S., Dhama, K., Chaubey, K.K., Kumar, N., Singh, P.K., Sohal, J.S., Gupta, S., Vir Singh, A., Verma, A.K., Tiwari, R. :
Impact of host genetics on susceptibility and resistance to Mycobacterium avium subspecies Paratuberculosis infection in domestic ruminants. Pak J Biol Sci 16:251-66, 2013. Pubmed reference: 24498788.
1996 Chiodini, R.J. :
Immunology: resistance to paratuberculosis. Vet Clin North Am Food Anim Pract 12:313-43, 1996. Pubmed reference: 8828108.

Edit History

  • Created by Frank Nicholas on 08 Feb 2014
  • Changed by Imke Tammen2 on 19 Apr 2021
  • Changed by Imke Tammen2 on 17 Sep 2021