OMIA 001990-10036 : Cancer, TP53-related in Mesocricetus auratus

In other species: pig

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 109800 (trait) , 114480 (trait) , 137215 (trait) , 601626 (trait) , 211980 (trait) , 260350 (trait) , 614470 (trait) , 202300 (trait) , 114500 (trait) , 114550 (trait) , 607107 (trait) , 259500 (trait) , 614740 (trait) , 137800 (trait) , 191170 (gene) , 190070 (gene) , 151623 (trait)

Mendelian trait/disorder: yes

Considered a defect: yes

Key variant known: no

Species-specific description: Miao et al. (2021) describe a cancer phenotype in TP53 knockout golden Syrian hamsters.

This phene includes references to studies involving genetically modified organisms (GMO).

Reference


2021 Miao, J., Li, R., Wettere, A.J.V., Guo, H., Tabaran, A.F., O'Sullivan, M.G., Carlson, T., Scott, P.M., Chen, K., Gao, D., Li, H., Wang, Y., Wang, Z., Cormier, R.T. :
Cancer spectrum in TP53-deficient golden Syrian hamsters: A new model for Li-Fraumeni syndrome. J Carcinog 20:18, 2021. Pubmed reference: 34729050. DOI: 10.4103/jcar.jcar_18_21.

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  • Created by Imke Tammen2 on 08 Nov 2021