OMIA 002054-9823 : Tumour in Sus scrofa

Mendelian trait/disorder: yes

Considered a defect: yes

Key variant known: no

Species-specific description: Susceptibility to tumours in pigs has been created artificially by CRISPR/Cas9-mediated gene targeting of the tumour supressor RUNX3; producing genetically-modified organisms (GMO)

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
RUNX3 runt-related transcription factor 3 Sus scrofa - no genomic information (-..-) RUNX3 Homologene, Ensembl, NCBI gene


2016 Kang, J.T., Ryu, J., Cho, B., Lee, E.J., Yun, Y.J., Ahn, S., Lee, J., Ji, D.Y., Lee, K., Park, K.W. :
Generation of RUNX3 knockout pigs using CRISPR/Cas9-mediated gene targeting. Reprod Domest Anim :, 2016. Pubmed reference: 27696566. DOI: 10.1111/rda.12775.

Edit History

  • Created by Frank Nicholas on 17 Oct 2016