OMIA 002061-345164 : Feather colour, light brown in Falco cherrug
change and a premature stop codon at position 81 of the deduced protein sequence, which in the wild-type form contains 536 amino acids."Associated gene:
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|TYRP1||tyrosinase-related protein 1||Falco cherrug||-||no genomic information (-..-)||TYRP1||Homologene, Ensembl, NCBI gene|
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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Feather colour, light brown||TYRP1||complex rearrangement||c.79C>T and c.79_80insT||in exon 1, resulting in "a frameshift change and a premature stop codon at position 81 of the deduced protein sequence, which in the wild-type form contains 536 amino acids.||2017||27611661|
|2017||Cortimiglia, C., Castiglioni, B., Pizzi, F., Stella, A., Capra, E. :|
|Involvement of tyrosinase-related protein 1 gene in the light brown plumage phenotype of Falco cherrug. Anim Genet 48:125-126, 2017. Pubmed reference: 27611661. DOI: 10.1111/age.12506.|
- Created by Frank Nicholas on 19 Oct 2016
- Changed by Frank Nicholas on 02 Mar 2017