OMIA:002353 : Limb movement, synchronic, EFNB3-related

Categories: Limbs / fins / digit / tail phene

Links to MONDO diseases: No links.

Cross-species summary: "Flight in birds evolved through patterning of the wings from forelimbs and transition from alternating gait to synchronous flapping. In mammals, the spinal midline guidance molecule ephrin-B3 [EFNB3] instructs the wiring that enables limb alternation, and its deletion leads to synchronous hopping gait." (Haimson et al. 2021)

Species in which this phene is found:
birds (Aves)
fowls (Galliformes)
chicken (Gallus gallus)
turkey (Meleagris gallopavo)
Japanese quail (Coturnix japonica)

Edit History


  • Created by Imke Tammen2 on 17 Jun 2021
  • Changed by Imke Tammen2 on 17 Jun 2021
  • Changed by Imke Tammen2 on 29 Oct 2022