OMIA:002400-9925 : Casein, kappa in Capra hircus (goat)

In other species: horse , taurine cattle , domestic yak

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Possibly relevant human trait(s) and/or gene(s) (MIM number): 601695 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Considered a defect: no

Key variant known: no

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2021). OMIA:002400-9925: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Dettori, M.L., Pazzola, M., Noce, A., Landi, V., Vacca, G.M. :
Variations in casein genes are associated with milk protein and fat contents in Sarda goats (Capra hircus), with an important role of CSN1S2 for milk yield. Animals (Basel) 14:56, 2023. Pubmed reference: 38200787. DOI: 10.3390/ani14010056.
Fernández Álvarez, J., Navas González, F.J., León Jurado, J.M., González Ariza, A., Martínez Martínez, M.A., Pastrana, C.I., Pizarro Inostroza, M.G., Delgado Bermejo, J.V. :
Discriminant canonical tool for inferring the effect of αS1, αS2, β, and κ casein haplotypes and haplogroups on zoometric/linear appraisal breeding values in Murciano-Granadina goats. Front Vet Sci 10:1138528, 2023. Pubmed reference: 37483293. DOI: 10.3389/fvets.2023.1138528.
2022 Rahmatalla, S.A., Arends, D., Brockmann, G.A. :
Review: Genetic and protein variants of milk caseins in goats. Front Genet 13:995349, 2022. Pubmed reference: 36568379. DOI: 10.3389/fgene.2022.995349.
2019 Gautam, D., Vats, A., Verma, M., Rout, P.K., Meena, A.S., Ali, M., Deepika, S., De, S. :
Genetic variation in CSN3 exon 4 region of Indian goats and a new nomenclature of CSN3 variants. Anim Genet 50:191-192, 2019. Pubmed reference: 30724371. DOI: 10.1111/age.12767.
2015 Singh, L.V., Jayakumar, S., Sharma, A., Gupta, S.K., Dixit, S.P., Gupta, N., Gupta, S.C. :
Comparative screening of single nucleotide polymorphisms in β-casein and κ-casein gene in different livestock breeds of India. Meta Gene 4:85-91, 2015. Pubmed reference: 25905036. DOI: 10.1016/j.mgene.2015.03.005.
2013 Jemmali, B., Ben Gara, A., Selmi, H., Ammari, Z., Bouheni, C., Ben Larbi, M., Hammami, M., Amraoui, M., Kamoun, M., Rouissi, H., Rekik, B. :
Kappa casein gene polymorphism in local Tunisian goats. Pak J Biol Sci 16:2031-5, 2013. Pubmed reference: 24517024. DOI: 10.3923/pjbs.2013.2031.2035.
2011 Caravaca, F., Ares, J.L., Carrizosa, J., Urrutia, B., Baena, F., Jordana, J., Badaoui, B., Sànchez, A., Angiolillo, A., Amills, M., Serradilla, J.M. :
Effects of α s1-casein (CSN1S1) and κ-casein (CSN3) genotypes on milk coagulation properties in Murciano-Granadina goats. J Dairy Res 78:32-7, 2011. Pubmed reference: 21214964. DOI: 10.1017/S002202991000083X.
Dagnachew, B.S., Thaller, G., Lien, S., Ådnøy, T. :
Casein SNP in Norwegian goats: additive and dominance effects on milk composition and quality. Genet Sel Evol 43:31, 2011. Pubmed reference: 21864407. DOI: 10.1186/1297-9686-43-31.
2010 Clop, A., Zidi, A., Amills, M. :
Identification of positively selected sites in the goat kappa casein (CSN3) gene. Anim Genet 41:332, 2010. Pubmed reference: 19968644. DOI: 10.1111/j.1365-2052.2009.02001.x.
2007 Chiatti, F., Chessa, S., Bolla, P., Cigalino, G., Caroli, A., Pagnacco, G. :
Effect of kappa-casein polymorphism on milk composition in the Orobica goat. J Dairy Sci 90:1962-6, 2007. Pubmed reference: 17369237. DOI: 10.3168/jds.2006-508.
2005 Prinzenberg, E.M., Gutscher, K., Chessa, S., Caroli, A., Erhardt, G. :
Caprine kappa-casein (CSN3) polymorphism: new developments in molecular knowledge. J Dairy Sci 88:1490-8, 2005. Pubmed reference: 15778318. DOI: 10.3168/jds.S0022-0302(05)72817-4.
2004 Jann, O.C., Prinzenberg, E.M., Luikart, G., Caroli, A., Erhardt, G. :
High polymorphism in the kappa-casein (CSN3) gene from wild and domestic caprine species revealed by DNA sequencing. J Dairy Res 71:188-95, 2004. Pubmed reference: 15190947. DOI: 10.1017/s0022029904000093.
2003 Chessa, S., Budelli, E., Gutscher, K., Caroli, A., Erhardt, G. :
Short communication: Simultaneous identification of five kappa-casein (CSN3) alleles in domestic goat by polymerase chain reaction-single strand conformation polymorphism. J Dairy Sci 86:3726-9, 2003. Pubmed reference: 14672203. DOI: 10.3168/jds.S0022-0302(03)73978-2.
2001 Caroli, A., Jann, O., Budelli, E., Bolla, P., Jäger, S., Erhardt, G. :
Genetic polymorphism of goat kappa-casein (CSN3) in different breeds and characterization at DNA level. Anim Genet 32:226-30, 2001. Pubmed reference: 11531704. DOI: 10.1046/j.1365-2052.2001.00765.x.

Edit History

  • Created by Imke Tammen2 on 27 Aug 2021
  • Changed by Imke Tammen2 on 27 Aug 2021