OMIA:002466-1553461 : Beak colour, BCO2-related in Camarhynchus heliobates
In other species: medium ground-finch , large cactus finch , sharp-beaked ground finch , small ground finch , large ground finch , common cactus finch , woodpecker finch , small tree finch , medium tree finch , large tree finch , Española cactus finch & Genovesa ground finch , Cocos finch , common canary
Categories: Pigmentation phene
Possibly relevant human trait(s) and/or gene(s) (MIM number): 611740 (gene)
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal recessive
Considered a defect: no
Key variant known: yes
Year key variant first reported: 2021
Cross-species summary: Bill colour, BCO2-related
Species-specific description: Enbody et al. (2021) "report a combined field and molecular-genetic investigation of a nestling beak color polymorphism in Darwin's finches. ... we show that the polymorphism arose in the Galápagos half a million years ago through a mutation associated with regulatory change in the BCO2 gene and is shared by 14 descendant species."
See 'OMIA 002466-48883 : Beak colour, BCO2-related in Geospiza fortis' for information on history, inheritance, mapping and molecular basis.
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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
|OMIA Variant ID||Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Source of Genetic Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Inferred EVA rsID||Year Published||PubMed ID(s)||Acknowledgements|
|1375||Beak colour, yellow||BCO2||synonymous||Naturally occurring variant||24||g.6166878G>A||p.(V?V)||synonymous change 32 bp into exon 4||2021||34687609|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2021||Enbody, E.D., Sprehn, C.G., Abzhanov, A., Bi, H., Dobreva, M.P., Osborne, O.G., Rubin, C.J., Grant, P.R., Grant, B.R., Andersson, L. :|
|A multispecies BCO2 beak color polymorphism in the Darwin's finch radiation. Curr Biol 31:5597-5604, 2021. Pubmed reference: 34687609 . DOI: 10.1016/j.cub.2021.09.085.|
|2014||Grant P.R., Grant B.R. :|
|40 Years of Evolution: Darwin’s Finches on Daphne Major Island. Princeton University Press :, 2014.|
|1989||Grant B.R., Grant P.R. :|
|Evolutionary Dynamics of a Natural Population: The Large Cactus Finch of the Galapagos University of Chicago Press, :, 1989.|
|1979||Grant P.R., Boag P.T., Schluter D. :|
|A bill color polymorphism in young Darwin’s finches. Auk 96:800-802, 1979. DOI: https://doi.org/10.1093/auk/96.4.800.|
- Created by Imke Tammen2 on 02 Nov 2021
- Changed by Imke Tammen2 on 02 Nov 2021