OMIA 002466-48882 : Beak colour, BCO2-related in Geospiza conirostris

In other species: medium ground-finch , sharp-beaked ground finch , small ground finch , large ground finch , common cactus finch , mangrove finch , woodpecker finch , small tree finch , medium tree finch , large tree finch , Española cactus finch & Genovesa ground finch , Cocos finch

Possibly relevant human trait(s) and/or gene(s) (MIM number): 611740 (gene)

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: no

Key variant known: yes

Year key variant first reported: 2021

Species-specific description: Enbody et al. (2021) "report a combined field and molecular-genetic investigation of a nestling beak color polymorphism in Darwin's finches. ... we show that the polymorphism arose in the Galápagos half a million years ago through a mutation associated with regulatory change in the BCO2 gene and is shared by 14 descendant species."

See 'OMIA 002466-48883 : Beak colour, BCO2-related in Geospiza fortis' for information on history, inheritance, mapping and molecular basis.

Variants

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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.

Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.

OMIA Variant ID Breed(s) Variant Phenotype Gene Allele Type of Variant Source of Genetic Variant Reference Sequence Chr. g. or m. c. or n. p. Verbal Description EVA ID Inferred EVA rsID Year Published PubMed ID(s) Acknowledgements
1375 Beak colour, yellow BCO2 synonymous Naturally occurring variant 24 g.6166878G>A p.(V?V) synonymous change 32 bp into exon 4 2021 34687609

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Enbody, E.D., Sprehn, C.G., Abzhanov, A., Bi, H., Dobreva, M.P., Osborne, O.G., Rubin, C.J., Grant, P.R., Grant, B.R., Andersson, L. :
A multispecies BCO2 beak color polymorphism in the Darwin's finch radiation. Curr Biol 31:5597-5604, 2021. Pubmed reference: 34687609. DOI: 10.1016/j.cub.2021.09.085.
2014 Grant P.R., Grant B.R. :
40 Years of Evolution: Darwin’s Finches on Daphne Major Island. Princeton University Press :, 2014.
1989 Grant B.R., Grant P.R. :
Evolutionary Dynamics of a Natural Population: The Large Cactus Finch of the Galapagos University of Chicago Press, :, 1989.
1979 Grant P.R., Boag P.T., Schluter D. :
A bill color polymorphism in young Darwin’s finches. Auk 96:800-802, 1979. DOI: https://doi.org/10.1093/auk/96.4.800.

Edit History


  • Created by Imke Tammen2 on 02 Nov 2021
  • Changed by Imke Tammen2 on 02 Nov 2021