OMIA 002492-9544 : Amyotrophic lateral sclerosis, TARDBP-related in Macaca mulatta

In other species: crab-eating macaque , pig

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 605078 (gene) , 612069 (trait)

Mendelian trait/disorder: yes

Considered a defect: yes

Key variant known: no

Species-specific description: This phene includes references to studies involving genetically modified organisms (GMO).

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Yang, W., Chen, X., Li, S., Li, X.J. :
Genetically modified large animal models for investigating neurodegenerative diseases. Cell Biosci 11:218, 2021. Pubmed reference: 34933675. DOI: 10.1186/s13578-021-00729-8.
2019 Yin, P., Guo, X., Yang, W., Yan, S., Yang, S., Zhao, T., Sun, Q., Liu, Y., Li, S., Li, X.J. :
Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains. Acta Neuropathol 137:919-937, 2019. Pubmed reference: 30810811. DOI: 10.1007/s00401-019-01979-0.

Edit History


  • Created by Imke Tammen2 on 09 Jan 2022