OMIA:002660-9031 : Resistance/susceptibility to avian influenza virus in Gallus gallus
In other species: Mallard
Categories: Immune system phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Species-specific description: Byun et al. (2017) "used recombinant lentiviruses to generate transgenic [TG] chickens expressing the 3D8 scFv gene under the control of the chicken β-actin promoter. ... [Their] results suggest that the transgenic chickens developed in this study could be useful for controlling potential within-flock AIV transmission." Yang et al. (2023) compared various parameters in non-TG and TG offspring female chickens: "Some serum parameters and cytokines were significantly different ... . Despite these differences, the mortality rates, body weight, egg production rates, and egg weight were not significantly different in the experimental groups of non-TG and TG offspring female chickens ... ."
This phene includes references to studies involving gene edited or genetically modified organisms (GMO).
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2023||Bertram, H., Wilhelmi, S., Rajavel, A., Boelhauve, M., Wittmann, M., Ramzan, F., Schmitt, A.O., Gültas, M. :|
|Comparative investigation of coincident single nucleotide polymorphisms underlying avian influenza viruses in chickens and ducks. Biology (Basel) 12:, 2023. Pubmed reference: 37508399 . DOI: 10.3390/biology12070969.|
|Bryson, K.J., Sives, S., Lee, H.M., Borowska, D., Smith, J., Digard, P., Vervelde, L. :|
|Comparative analysis of different inbred chicken lines highlights how a hereditary inflammatory state affects susceptibility to avian influenza virus. Viruses 15:, 2023. Pubmed reference: 36992300 . DOI: 10.3390/v15030591.|
|Yang, H., Ock, S.A., Lee, S., Park, M.R., Kim, S., No, J., Oh, K.B., Wi, H., Jung, S.K., Jo, Y.J., Lee, B.R., Lee, M., Byun, S.J. :|
|Mortality, growth, and egg production do not differ between nontransgenic and transgenic female chickens with ubiquitous expression of the 3D8 single chain variable fragment gene. Poult Sci 102:102802, 2023. Pubmed reference: 37307631 . DOI: 10.1016/j.psj.2023.102802.|
|2018||Drobik-Czwarno, W., Wolc, A., Fulton, J.E., Jankowski, T., Arango, J., O'Sullivan, N.P., Dekkers, J.C.M. :|
|Genetic basis of resistance to avian influenza in different commercial varieties of layer chickens. Poult Sci 97:3421-3428, 2018. Pubmed reference: 29924353 . DOI: 10.3382/ps/pey233.|
|2017||June Byun, S., Yuk, S.S., Jang, Y.J., Choi, H., Jeon, M.H., Erdene-Ochir, T.O., Kwon, J.H., Noh, J.Y., Sun Kim, J., Gyu Yoo, J., Song, C.S. :|
|Transgenic chickens expressing the 3D8 single chain variable fragment protein suppress avian influenza transmission. Sci Rep 7:5938, 2017. Pubmed reference: 28724948 . DOI: 10.1038/s41598-017-05270-8.|
|2016||Ruiz-Hernandez, R., Mwangi, W., Peroval, M., Sadeyen, J.R., Ascough, S., Balkissoon, D., Staines, K., Boyd, A., McCauley, J., Smith, A., Butter, C. :|
|Host genetics determine susceptibility to avian influenza infection and transmission dynamics. Sci Rep 6:26787, 2016. Pubmed reference: 27279280 . DOI: 10.1038/srep26787.|
- Changed by Imke Tammen2 on 31 Mar 2023
- Created by Imke Tammen2 on 31 Mar 2023
- Changed by Imke Tammen2 on 15 Jun 2023