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Gene TP53 : tumor protein p53 in Canis lupus familiaris

 See the equivalent entry at NCBI

In other species: pig , crab-eating macaque , golden hamster

Symbol: TP53

Synonyms: P53

Description: tumor protein p53

Type of gene: protein-coding

NCBI gene id: 403869

Other designations: cellular tumor antigen p53|mutant P53 tumor suppressor protein|tumor protein p53 (Li-Fraumeni syndrome)|tumor suppressor p53|tumor suppressor protein

Links: Homologene , Ensembl

Genomic location: 5:32678721..32665395 [Chromosome accession NC_051809.1]

Related phenes:

OMIA:000620-9615 : Histiocytosis, malignant in Canis lupus familiaris

OMIA:001990-9615 : Cancer, TP53-related in Canis lupus familiaris

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2012 Marfe, G., De Martino, L., Tafani, M., Irno-Consalvo, M., Pasolini, M.P., Navas, L., Papparella, S., Gambacurta, A., Paciello, O. :
A multicancer-like syndrome in a dog characterized by p53 and cell cycle-checkpoint kinase 2 (CHK2) mutations and sirtuin gene (SIRT1) down-regulation. Res Vet Sci 93:240-5, 2012. Pubmed reference: 21890154. DOI: 10.1016/j.rvsc.2011.07.030.
York, D., Higgins, R.J., LeCouteur, R.A., Wolfe, A.N., Grahn, R., Olby, N., Campbell, M., Dickinson, P.J. :
TP53 mutations in canine brain tumors. Vet Pathol 49:796-801, 2012. Pubmed reference: 22002975. DOI: 10.1177/0300985811424734.
1996 Guevara-Fujita, M.L., Loechel, R., Venta, P.J., Yuzbasiyan-Gurkan, V., Brewer, G.J. :
Chromosomal assignment of seven genes on canine chromosomes by fluorescence in situ hybridization Mamm Genome 7:268-70, 1996. Pubmed reference: 8661696. DOI: 10.1007/s003359900080.
Vanleeuwen, I.S., Hellmen, E., Cornelisse, C.J., Vandenburgh, B., Rutteman, G.R. :
P53 mutations in mammary tumor cell lines and corresponding tumor tissues in the dog Anticancer Research 16:3737-3744, 1996. Pubmed reference: 9042250.