OMIA 000080-9823 : Atherosclerosis in Sus scrofa |
In other species:
rock pigeon
,
dog
,
domestic cat
,
Japanese quail
Possibly relevant human trait(s) and/or gene(s) (MIM number):
108725 (trait)
Mendelian trait/disorder:
unknown
Considered a defect:
yes
Cross-species summary:
A common form of arteriosclerosis in which deposits of yellowing plaques (atheromas) containing cholesterol and other lipid material are formed within the arteries.
Species-specific description:
A strain of pig that spontaneously develops atherosclerosis has been developed by selection (Skold and Getty, 1961; Gal et al., 1990), and is used as an animal model for medical studies of the same disease in humans.
Inheritance:
familial
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2021 | Zhang, Y., Fatima, M., Hou, S., Bai, L., Zhao, S., Liu, E. : | |
| Research methods for animal models of atherosclerosis (Review). Mol Med Rep 24:871, 2021. Pubmed reference: 34713295. DOI: 10.3892/mmr.2021.12511. | ||
| 1996 | Ali, M.N., Mazur, W., Kleiman, N.S., Rodgers, G.P., Abukhalil, J.M., French, B.A., Raizner, A.E. : | |
| Inhibition of coronary restenosis by antithrombin iii in atherosclerotic swine Coronary Artery Disease 7:851-861, 1996. Pubmed reference: 8993944. | ||
| 1990 | Armstrong, M.L., Heistad, D.D. : | |
| Animal Models of Atherosclerosis Atherosclerosis 85:15-23, 1990. Pubmed reference: 2282105. | ||
| Gal, D., Rongione, A.J., Slovenkai, G.A., Dejesus, S.T., Lucas, A., Fields, C.D., Isner, J.M. : | ||
| Atherosclerotic Yucatan Microswine - An Animal Model with High- Grade, Fibrocalcific, Nonfatty Lesions Suitable for Testing Catheter-Based Interventions American Heart Journal 119:291-300, 1990. Pubmed reference: 2301218. | ||
| Rapacz, J., Hasler-Rapacz, J. : | ||
| The Pig and Its Plasma Lipoprotein Polymorphism in Studies of Atherosclerosis Journal of Animal Breeding and Genetics-Zeitschrift Fur Tierzuchtung und Zuchtungsbiologie :131-146, 1990. | ||
| 1989 | Rapacz, J., Hasler-Rapacz, J. : | |
| Animal Models - The Pig Genetic Factors in Atherosclerosis : Approaches and Model Systems 12:139-169, 1989. | ||
| 1986 | Rapcz, J., Hasler-Rapacz, J., Taylor, K.M., Checovich, W.J., Attie, A.D. : | |
| Lipoprotein mutations in pigs are associated with elevated plasma cholesterol and atherosclerosis Science 234:1573-1577, 1986. Pubmed reference: 3787263. | ||
| 1963 | Downie, H.G., Mustard, J.F., Rowsell, H.C. : | |
| Swine atherosclerosis: the relationships of lipids and blood coagulation to its development Annals of the New York Academy of Sciences 104:539-562, 1963. | ||
| 1961 | Skold, B.H., Getty, R. : | |
| Spontaneous atherosclerosis of swine Journal of the American Veterinary Medical Association 139:655-660, 1961. |
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- Created by Frank Nicholas on 06 Sep 2005