OMIA:000080-9823 : Atherosclerosis in Sus scrofa
In other species: rock pigeon , dog , domestic cat , golden hamster , Japanese quail
Categories: Cardiovascular system phene
Possibly relevant human trait(s) and/or gene(s) (MIM number): 108725 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: A common form of arteriosclerosis in which deposits of yellowing plaques (atheromas) containing cholesterol and other lipid material are formed within the arteries.
Species-specific description: A strain of pig that spontaneously develops atherosclerosis has been developed by selection (Skold and Getty, 1961; Gal et al., 1990), and is used as an animal model for medical studies of the same disease in humans.
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2021||Zhang, Y., Fatima, M., Hou, S., Bai, L., Zhao, S., Liu, E. :|
|Research methods for animal models of atherosclerosis (Review). Mol Med Rep 24:871, 2021. Pubmed reference: 34713295 . DOI: 10.3892/mmr.2021.12511.|
|1996||Ali, M.N., Mazur, W., Kleiman, N.S., Rodgers, G.P., Abukhalil, J.M., French, B.A., Raizner, A.E. :|
|Inhibition of coronary restenosis by antithrombin iii in atherosclerotic swine Coronary Artery Disease 7:851-861, 1996. Pubmed reference: 8993944 .|
|1990||Armstrong, M.L., Heistad, D.D. :|
|Animal Models of Atherosclerosis Atherosclerosis 85:15-23, 1990. Pubmed reference: 2282105 .|
|Gal, D., Rongione, A.J., Slovenkai, G.A., Dejesus, S.T., Lucas, A., Fields, C.D., Isner, J.M. :|
|Atherosclerotic Yucatan Microswine - An Animal Model with High- Grade, Fibrocalcific, Nonfatty Lesions Suitable for Testing Catheter-Based Interventions American Heart Journal 119:291-300, 1990. Pubmed reference: 2301218 .|
|Rapacz, J., Hasler-Rapacz, J. :|
|The Pig and Its Plasma Lipoprotein Polymorphism in Studies of Atherosclerosis Journal of Animal Breeding and Genetics-Zeitschrift Fur Tierzuchtung und Zuchtungsbiologie :131-146, 1990.|
|1989||Rapacz, J., Hasler-Rapacz, J. :|
|Animal Models - The Pig Genetic Factors in Atherosclerosis : Approaches and Model Systems 12:139-169, 1989.|
|1986||Rapcz, J., Hasler-Rapacz, J., Taylor, K.M., Checovich, W.J., Attie, A.D. :|
|Lipoprotein mutations in pigs are associated with elevated plasma cholesterol and atherosclerosis Science 234:1573-1577, 1986. Pubmed reference: 3787263 .|
|1963||Downie, H.G., Mustard, J.F., Rowsell, H.C. :|
|Swine atherosclerosis: the relationships of lipids and blood coagulation to its development Annals of the New York Academy of Sciences 104:539-562, 1963.|
|1961||Skold, B.H., Getty, R. :|
|Spontaneous atherosclerosis of swine Journal of the American Veterinary Medical Association 139:655-660, 1961.|
- Created by Frank Nicholas on 06 Sep 2005