OMIA 000162-10036 : Cardiomyopathy, dilated in Mesocricetus auratus
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|SGCD||sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)||Mesocricetus auratus||-||no genomic information (-..-)||SGCD||Homologene, Ensembl, NCBI gene|
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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
|OMIA Variant ID||Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Source of Genetic Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Inferred EVA rsID||Year Published||PubMed ID(s)||Acknowledgements|
|651||Cardiomyopathy, dilated||SGCD||deletion, gross (>20)||Naturally occurring variant||genomic deletion was found to be located at 6.1 kb 5' upstream of the second exon of Î´-SG gene, and its 5' upstream region of more than 27.4 kb, including the authentic first exon of Î´-SG gene, was deleted||1997||9391120|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2013||Maekawa, K., Hirayama, A., Iwata, Y., Tajima, Y., Nishimaki-Mogami, T., Sugawara, S., Ueno, N., Abe, H., Ishikawa, M., Murayama, M., Matsuzawa, Y., Nakanishi, H., Ikeda, K., Arita, M., Taguchi, R., Minamino, N., Wakabayashi, S., Soga, T., Saito, Y. :|
|Global metabolomic analysis of heart tissue in a hamster model for dilated cardiomyopathy. J Mol Cell Cardiol 59:76-85, 2013. Pubmed reference: 23454301. DOI: 10.1016/j.yjmcc.2013.02.008.|
|1997||Nigro, V., Okazaki, Y., Belsito, A., Piluso, G., Matsuda, Y., Politano, L., Nigro, G., Ventura, C., Abbondanza, C., Molinari, A.M., Acampora, D., Nishimura, M., Hayashizaki, Y., Puca, G.A. :|
|Identification of the Syrian hamster cardiomyopathy gene. Hum Mol Genet 6:601-7, 1997. Pubmed reference: 9097966.|
|Sakamoto, A., Ono, K., Abe, M., Jasmin, G., Eki, T., Murakami, Y., Masaki, T., Toyooka, T., Hanaoka, F. :|
|Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, delta-sarcoglycan, in hamster - an animal model of disrupted dystrophin-associated glycoprotein complex Proceedings of the National Academy of Sciences of the United States of America 94:13873-13878, 1997. Pubmed reference: 9391120.|
- Created by Frank Nicholas on 12 Sep 2005
- Changed by Frank Nicholas on 08 Dec 2011
- Changed by Frank Nicholas on 21 Mar 2012
- Changed by Frank Nicholas on 26 Feb 2014