OMIA 000162-9103 : Cardiomyopathy, dilated in Meleagris gallopavo
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|TNNT2||troponin T type 2 (cardiac)||Meleagris gallopavo||28||NC_015038.2 (265422..273601)||TNNT2||Homologene, Ensembl, NCBI gene|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
|OMIA Variant ID||Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Source of Genetic Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Inferred EVA rsID||Year Published||PubMed ID(s)||Acknowledgements|
|397||Cardiomyopathy, dilated||TNNT2||splicing||Naturally occurring variant||delGGGCTCCTC||2002||11886865|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2015||Frame, D.D., Kelly, E.J., Van Wettere, A. :|
|Dilated Cardiomyopathy in a Rio Grande Wild Turkey (Meleagris gallopavo intermedia) in Southern Utah, USA, 2013. J Wildl Dis 51:790-2, 2015. Pubmed reference: 25919467. DOI: 10.7589/2014-09-228.|
|2007||Lin, K.C., Xu, J., Kamara, D., Geng, T., Gyenai, K., Reed, K.M., Smith, E.J. :|
|DNA sequence and haplotype variation in two candidate genes for dilated cardiomyopathy in the turkey Meleagris gallopavo. Genome 50:463-9, 2007. Pubmed reference: 17612615. DOI: 10.1139/g07-022.|
|Reed, K.M., Mendoza, K.M., Hu, G.R., Sullivan, L.R., Grace, M.W., Chaves, L.D., Kooyman, D.L. :|
|Genomic analysis of genetic markers associated with inherited cardiomyopathy (round heart disease) in the turkey (Meleagris gallopavo). Anim Genet 38:211-7, 2007. Pubmed reference: 17433016. DOI: 10.1111/j.1365-2052.2007.01589.x.|
|2006||Lin, K.C., Gyenai, K., Pyle, R.L., Geng, T., Xu, J., Smith, E.J. :|
|Candidate gene expression analysis of toxin-induced dilated cardiomyopathy in the turkey (Meleagris gallopavo). Poult Sci 85:2216-21, 2006. Pubmed reference: 17135679. DOI: 10.1093/ps/85.12.2216.|
|2004||Biesiadecki, BJ., Schneider, KL., Yu, ZB., Chong, SM., Jin, JP. :|
|An R111C polymorphism in wild turkey cardiac troponin I accompanying the dilated cardiomyopathy-related abnormal splicing variant of cardiac troponin T with potentially compensatory effects. J Biol Chem 279:13825-32, 2004. Pubmed reference: 14736877. DOI: 10.1074/jbc.M314225200.|
|2002||Biesiadecki, B.J., Jin, J.P. :|
|Exon skipping in cardiac troponin T of turkeys with inherited dilated cardiomyopathy Journal of Biological Chemistry 277:18459-18468, 2002. Pubmed reference: 11886865. DOI: 10.1074/jbc.M200788200.|
|1996||Genao, A., Seth, K., Schmidt, U., Carles, M., Gwathmey, J.K. :|
|Dilated cardiomyopathy in turkeys - an animal model for the study of human heart failure Laboratory Animal Science 46:399-404, 1996. Pubmed reference: 8872990.|
|1993||Gruver, E.J., Glass, M.G., Marsh, J.D., Gwathmey, J.K. :|
|An Animal Model of Dilated Cardiomyopathy - Characterization of Dihydropyridine Receptors and Contractile Performance American Journal of Physiology 265:H1704-H1711, 1993. Pubmed reference: 8238583.|
- Created by Frank Nicholas on 29 Nov 2005
- Changed by Frank Nicholas on 12 Oct 2011
- Changed by Frank Nicholas on 12 Dec 2011
- Changed by Frank Nicholas on 22 Jan 2012