OMIA 000214-9844 : Coat colour, white spotting in Lama glama
In other species: dog , domestic cat , horse , cattle , domestic guinea pig , water buffalo Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 193510 (trait) , 103500 (trait) , 156845 (gene) Mendelian trait/disorder: unknown Considered a defect: no Cross-species summary: Variable degree of white spotting ranging from tiny white spots up to completely white animals. The absence of pigment is caused by the absence of skin melanocytes ("leucism"), not by failure in the biochemical reactions required for pigment synthesis. Molecular basis: Anello et al. (2019) reported that although "downregulation of KIT and MITF-M expression is involved in white phenotype production in llamas, the causative gene of white coat color remains unknown."
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2020||Jost, S.M., Knoll, A., Lühken, G., Drögemüller, C., Zanolari, P. :|
|Prevalence of coat colour traits and congenital disorders of South American camelids in Austria, Germany and Switzerland. Acta Vet Scand 62:56, 2020. Pubmed reference: 32948208. DOI: 10.1186/s13028-020-00554-y.|
|2019||Anello, M., Daverio, M.S., Silbestro, M.B., Vidal-Rioja, L., Di Rocco, F. :|
|Characterization and expression analysis of KIT and MITF-M genes in llamas and their relation to white coat color. Anim Genet 50:143-149, 2019. Pubmed reference: 30730042. DOI: 10.1111/age.12769.|
- Created by Frank Nicholas on 23 Sep 2019
- Changed by Frank Nicholas on 23 Sep 2019