In other species: domestic cat , dog , cattle , horse , water buffalo , llama

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 193510 (trait) , 103500 (trait) , 156845 (gene)

Mendelian trait/disorder: yes

Considered a defect: no

Key variant known: no

Cross-species summary: Variable degree of white spotting ranging from tiny white spots up to completely white animals. The absence of pigment is caused by the absence of skin melanocytes ("leucism"), not by failure in the biochemical reactions required for pigment synthesis.