OMIA:000219-7994 : Coloboma in Astyanax mexicanus

In other species: cattle , chicken , llama , horse , dog , domestic cat , snow leopard

Categories: Vision / eye phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 120200 (trait) , 120300 (trait) , 120330 (trait) , 120400 (trait) , 120430 (trait) , 120433 (trait) , 216800 (trait) , 216820 (trait) , 243910 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Colobomas are congenital eye abnormalities where normal tissue in or around the eye are missing.

Species-specific description: See also OMIA 002130-7994 : Coat colour, oculocutaneous albinism, OCA2-related in Astyanax mexicanus


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Sifuentes-Romero, I., Aviles, A.M., Carter, J.L., Chan-Pong, A., Clarke, A., Crotty, P., Engstrom, D., Meka, P., Perez, A., Perez, R., Phelan, C., Sharrard, T., Smirnova, M.I., Wade, A.J., Kowalko, J.E. :
Trait loss in evolution: What cavefish have taught us about mechanisms underlying eye regression. Integr Comp Biol :, 2023. Pubmed reference: 37218721 . DOI: 10.1093/icb/icad032.
2021 Devos, L., Agnès, F., Edouard, J., Simon, V., Legendre, L., El Khallouki, N., Barbachou, S., Sohm, F., Rétaux, S. :
Eye morphogenesis in the blind Mexican cavefish. Biol Open 10:, 2021. Pubmed reference: 34590124 . DOI: 10.1242/bio.059031.

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  • Created by Imke Tammen2 on 20 Oct 2021