In other species: cattle , llama , horse , dog , domestic cat , Mexican tetra

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 120200 (trait) , 120300 (trait) , 120330 (trait) , 120400 (trait) , 120430 (trait) , 120433 (trait) , 216800 (trait) , 216820 (trait) , 243910 (trait)

Mendelian trait/disorder: yes

Mode of inheritance: Z-linked recessive

Considered a defect: yes

Key variant known: no

Cross-species summary: Colobomas are congenital eye abnormalities where normal tissue in or around the eye are missing.

Species-specific symbol: co

Mapping: Robb et al. (2011) mapped this trait to chromosome GGA Zp (19,868,747-21,363,270)

Clinical features: "Hemizygous female mutants (Z-/W) are moderately to severely dwarfed with mild to severe cleft palate, some are lacking preaxial digits or have truncated wings and legs; some are edemic; the expression may be highly variable even with the same parents, temperature sensitive phenotypic variability" (Robb et al. (2011)