In other species: cattle , llama , horse , dog , domestic cat

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 120200 , 120300 , 120330 , 120400 , 120430 , 120433 , 216800 , 216820 , 243910

Mendelian trait/disorder: yes

Mode of inheritance: Z-linked recessive

Considered a defect: yes

Key variant known: no

Species-specific symbol: co

Mapping: Robb et al. (2011) mapped this trait to chromosome GGA Zp (19,868,747-21,363,270)

Clinical features: "Hemizygous female mutants (Z-/W) are moderately to severely dwarfed with mild to severe cleft palate, some are lacking preaxial digits or have truncated wings and legs; some are edemic; the expression may be highly variable even with the same parents, temperature sensitive phenotypic variability" (Robb et al. (2011)