OMIA 000319-9940 : Ears, folded (drop vs prick) in Ovis aries |
Paris et al. (2020) "performed a comprehensive genome‐wide analysis to identify regions under selection for ear morphology in 515 sheep from 17 breeds fixed for diverse ear phenotypes using 34k SNP genotyping data. GWASs for two ear type traits, size and erectness, revealed a single genome‐wide significant association on ovine chromosome 3. The derived marker alleles were enriched in sheep with large and/or floppy ears. The GWAS signal harboured the MSRB3 gene encoding methionine sulphoxide reductase B3, which has already been found to be associated with different ear types in other species. . . . Fine‐mapping suggested that the causal variant for large floppy ears most likely resides in a 175 kb interval downstream of the MSRB3 coding region."
Associated gene:Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
---|---|---|---|---|---|---|
MSRB3 | methionine sulfoxide reductase B3 | Ovis aries | 3 | NC_056056.1 (154683593..154503180) | MSRB3 | Homologene, Ensembl, NCBI gene |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2020 | Paris, J.M., Letko, A., Häfliger, I.M., Ammann, P., Drögemüller, C. : | |
Ear type in sheep is associated with the MSRB3 locus. Anim Genet 51:968-72, 2020. Pubmed reference: 32805068. DOI: 10.1111/age.12994. | ||
2015 | Wei, C., Wang, H., Liu, G., Wu, M., Cao, J., Liu, Z., Liu, R., Zhao, F., Zhang, L., Lu, J., Liu, C., Du, L. : | |
Genome-wide analysis reveals population structure and selection in Chinese indigenous sheep breeds. BMC Genomics 16:194, 2015. Pubmed reference: 25888314. DOI: 10.1186/s12864-015-1384-9. |
Edit History
- Created by Frank Nicholas on 19 Apr 2020
- Changed by Frank Nicholas on 19 Apr 2020
- Changed by Frank Nicholas on 23 Oct 2020