In other species: chicken , dog , domestic cat , horse , rabbit , golden hamster , Mongolian gerbil

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 104130 , 117100 , 121200 , 121201 , 125370 , 132090 , 132100 , 132300 , 159600 , 182610 , 203600 , 208700 , 220300 , 226750 , 226800 , 226810 , 226850 , 254770 , 254780 , 254800 , 266270 , 267740 , 270805 , 301900 , 310370 , 545000 , 600131 , 600143 , 600512 , 600513 , 600669 , 601068 , 245570

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: yes

Key variant known: yes

Key variant is published: no

Species-specific name: Idiopathic epilepsy

Species-specific symbol: IE

Clinical features: Age of onset (occurrence of the first seizure) can be variable, ranging from birth to several months of age. Occurrence and persistence of seizures may be influenced by environmental stressors such as temperature extremes (e.g., extreme cold during calving) or increased physical activity (e.g., processing at vaccination or weaning). Upon initial onset of seizures calves may appear to walk with a stiffened, irregular gait. During seizure episodes individuals will typically lie on their side with all limbs extended in a rigid state. Manual flexing of the limbs is possible, but return to the extended position occurs after release. Seizure episodes may last from several minutes to more than an hour. No anatomic abnormalities or histologic lesions detected. (text kindly provided by Dr J. Beever 4 Feb 2008))

Genetic testing: A DNA test has been developed by Dr Jon Beever, Department of Animal Sciences, University of Illinois.