OMIA:000428-9805 : Haemochromatosis in Diceros bicornis (black rhinoceros)

In other species: Ring-tailed lemur , Lesser dwarf lemur , white-tufted-ear marmoset , horse , red deer , taurine cattle , Sumatran rhinoceros , hill myna

Categories: Homeostasis / metabolism phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 231100 (trait) , 235200 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2013). OMIA:000428-9805: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2012 Klopfleisch, R., Olias, P. :
The pathology of comparative animal models of human haemochromatosis. J Comp Pathol 147:460-78, 2012. Pubmed reference: 23079103. DOI: 10.1016/j.jcpa.2012.09.001.
Olias, P., Mundhenk, L., Bothe, M., Ochs, A., Gruber, A.D., Klopfleisch, R. :
Iron overload syndrome in the black rhinoceros (Diceros bicornis): microscopical lesions and comparison with other rhinoceros species. J Comp Pathol 147:542-9, 2012. Pubmed reference: 22935088. DOI: 10.1016/j.jcpa.2012.07.005.
Paglia, D.E., Tsu, I.H. :
Review of laboratory and necropsy evidence for iron storage disease acquired by browser rhinoceroses. J Zoo Wildl Med 43:S92-104, 2012. Pubmed reference: 23156711.
2001 Beutler, E., West, C., Speir, J.A., Wilson, I.A., Worley, M. :
The hHFE gene of browsing and grazing rhinoceroses: a possible site of adaptation to a low-iron diet. Blood Cells Mol Dis 27:342-50, 2001. Pubmed reference: 11358396. DOI: 10.1006/bcmd.2001.0386.
2000 Paglia, D.E., Radcliffe, R.W. :
Anthracycline cardiotoxicity in a black rhinoceros (Diceros bicornis): evidence for impaired antioxidant capacity compounded by iron overload. Vet Pathol 37:86-8, 2000. Pubmed reference: 10643986.

Edit History

  • Created by Frank Nicholas on 03 May 2013