OMIA:000428-9913 : Haemochromatosis in Bos taurus (taurine cattle)
Categories: Homeostasis / metabolism phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Inheritance: The resemblance of this disorder to human haemochromatosis (see MIM entries above) leads to the expectation that this disorder in cattle is also inherited. O'Toole et al. (2001) provided supporting evidence for autosomal recessive inheritance from a test mating, but concluded "It was not possible to establish the pattern of inheritance because of the small number of pedigrees from affected cattle"
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2012||Klopfleisch, R., Olias, P. :|
|The pathology of comparative animal models of human haemochromatosis. J Comp Pathol 147:460-78, 2012. Pubmed reference: 23079103. DOI: 10.1016/j.jcpa.2012.09.001.|
|2004||Norrdin, RW., Hoopes, KJ., O'Toole, D. :|
|Skeletal changes in hemochromatosis of Salers cattle. Vet Pathol 41:612-23, 2004. Pubmed reference: 15557071. DOI: 10.1354/vp.41-6-612.|
|2001||O'Toole, D., Kelly, E.J., McAllister, M.M., Layton, A.W., Norrdin, R.W., Russell, W.C., Saeb-Parsy, K., Walker, A.P. :|
|Hepatic failure and hemochromatosis of Salers and Salers-cross cattle. Vet Pathol 38:372-89, 2001. Pubmed reference: 11467471.|
|1994||House, J.K., Smith, B.P., Maas, J., Lane, V.M., Anderson, B.C., Graham, T.W., Pino, M.V. :|
|Hemochromatosis in Salers Cattle Journal of Veterinary Internal Medicine 8:105-111, 1994. Pubmed reference: 8046672.|
|1991||Smith, B.P. :|
|Iron toxicosis in cattle. J Am Vet Med Assoc 198:10, 1991. Pubmed reference: 1995558.|
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 03 May 2013