OMIA:000485-9541 : Huntington disease in Macaca fascicularis (crab-eating macaque) |
In other species: Rhesus monkey , pig , sheep
Categories: Nervous system phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 143100 (trait) , 613004 (gene)
Links to MONDO diseases:
Mendelian trait/disorder: yes
Considered a defect: yes
Key variant known: no
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| HTT | huntingtin | Macaca fascicularis | 5 | NC_052259.1 (3228449..3397424) | HTT | Homologene, Ensembl , NCBI gene |
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2024). OMIA:000485-9541: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2024 | Han, B., Liang, W., Li, X.J., Li, S., Yan, S., Tu, Z. : |
| Large animal models for Huntington's disease research. Zool Res 45:2095-8137(2024)02-0275-09:275-283, 2024. Pubmed reference: 38485497. DOI: 10.24272/j.issn.2095-8137.2023.199. | |
| 2007 | Palfi, S., Brouillet, E., Jarraya, B., Bloch, J., Jan, C., Shin, M., Condé, F., Li, X.J., Aebischer, P., Hantraye, P., Déglon, N. : |
| Expression of mutated huntingtin fragment in the putamen is sufficient to produce abnormal movement in non-human primates. Mol Ther 15:1444-51, 2007. Pubmed reference: 17505477. DOI: 10.1038/sj.mt.6300185. |
Edit History
- Created by Imke Tammen2 on 08 Apr 2024
- Changed by Imke Tammen2 on 08 Apr 2024