OMIA 000485-9544 : Huntington disease in Macaca mulatta |
In other species:
pig
Possibly relevant human trait(s) and/or gene(s) (MIM number):
143100
Mendelian trait/disorder:
yes
Considered a defect:
yes
Key variant known:
no
Species-specific description:
Yang et al. (2008) developed "a transgenic model of HD in a rhesus macaque that expresses polyglutamine-expanded HTT". Resultant animals are genetically-modified organisms (GMO).
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2019 | Cho, I.K., Yang, B., Forest, C., Qian, L., Chan, A.W.S. : | |
| Amelioration of Huntington's disease phenotype in astrocytes derived from iPSC-derived neural progenitor cells of Huntington's disease monkeys. PLoS One 14:e0214156, 2019. Pubmed reference: 30897183. DOI: 10.1371/journal.pone.0214156. | ||
| Clever, F., Cho, I.K., Yang, J., Chan, A. : | ||
| Progressive Polyglutamine Repeat Expansion in Peripheral Blood Cells and Sperm of Transgenic Huntington's Disease Monkeys. J Huntingtons Dis :, 2019. Pubmed reference: 31561381. DOI: 10.3233/JHD-190359. | ||
| 2018 | Snyder, B.R., Chan, A.W.S. : | |
| Progress in developing transgenic monkey model for Huntington's disease. J Neural Transm (Vienna) 125:401-417, 2018. Pubmed reference: 29127484. DOI: 10.1007/s00702-017-1803-y. | ||
| 2017 | Meng, Y., Jiang, J., Bachevalier, J., Zhang, X., Chan, A.W. : | |
| Developmental Whole Brain White Matter Alterations in Transgenic Huntington's Disease Monkey. Sci Rep 7:379, 2017. Pubmed reference: 28336929. DOI: 10.1038/s41598-017-00381-8. | ||
| 2015 | Chang, R., Liu, X., Li, S., Li, X.J. : | |
| Transgenic animal models for study of the pathogenesis of Huntington's disease and therapy. Drug Des Devel Ther 9:2179-88, 2015. Pubmed reference: 25931812. DOI: 10.2147/DDDT.S58470. | ||
| Li, X.J., Li, S. : | ||
| Large Animal Models of Huntington's Disease. Curr Top Behav Neurosci 22:149-60, 2015. Pubmed reference: 24048953. DOI: 10.1007/7854_2013_246. | ||
| 2014 | Chan, A.W., Xu, Y., Jiang, J., Rahim, T., Zhao, D., Kocerha, J., Chi, T., Moran, S., Engelhardt, H., Larkin, K., Neumann, A., Cheng, H., Li, C., Nelson, K., Banta, H., Zola, S.M., Villinger, F., Yang, J., Testa, C.M., Mao, H., Zhang, X., Bachevalier, J. : | |
| A two years longitudinal study of a transgenic Huntington disease monkey. BMC Neurosci 15:36, 2014. Pubmed reference: 24581271. DOI: 10.1186/1471-2202-15-36. | ||
| 2013 | Laowtammathron, C., Chan, A.W. : | |
| Pluripotent hybrid stem cells from transgenic Huntington's disease monkey. Methods Mol Biol 1010:61-77, 2013. Pubmed reference: 23754219. DOI: 10.1007/978-1-62703-411-1_5. | ||
| 2008 | Yang, S.H., Cheng, P.H., Banta, H., Piotrowska-Nitsche, K., Yang, J.J., Cheng, E.C., Snyder, B., Larkin, K., Liu, J., Orkin, J., Fang, Z.H., Smith, Y., Bachevalier, J., Zola, S.M., Li, S.H., Li, X.J., Chan, A.W. : | |
| Towards a transgenic model of Huntington's disease in a non-human primate. Nature 453:921-4, 2008. Pubmed reference: 18488016. DOI: 10.1038/nature06975. | ||
| 1997 | Emerich, D.F., Winn, S.R., Hantraye, P.M., Peschanski, M., Chen, E.Y., Chu, Y., McDermott, P., Baetge, E.E., Kordower, J.H. : | |
| Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease. Nature 386:395-9, 1997. Pubmed reference: 9121555. DOI: 10.1038/386395a0. |
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- Created by Frank Nicholas on 30 Sep 2019
- Changed by Frank Nicholas on 30 Sep 2019