OMIA 000519-9796 : Hypoadrenocorticism in Equus caballus

In other species: dog , domestic cat , goat

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 240200 (trait) , 240300 (trait)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Hypoadrenocorticism, or Addison’s disease, results from insufficient secretion of steroid hormones (glucocorticoids and mineralocorticoids) from the adrenal glands. In primary hypoadrenocorticism the disease is due to changes to the adrenal cortex, while secondary hypoadrenocorticism refers to deficiency of ACTH, produced in the piturity gland. The disease can be further classified as typical (glucocorticoid and mineralocorticoid deficiency) with typical electrolyte changes or atypical (only glucocorticoid deficiency with no typical electrolyte changes). The atypical cases often progress to become typical.

Reference


1998 Couetil, L.L., Hoffman, A.M. :
Adrenal insufficiency in a neonatal foal Journal of the American Veterinary Medical Association 212:1594 ff., 1998.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005