You are here: OMIA / Search / OMIA:000519 / goat

OMIA:000519-9925 : Hypoadrenocorticism in Capra hircus (goat)

In other species: dog , domestic cat , horse

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 240200 (trait) , 240300 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Hypoadrenocorticism, or Addison’s disease, results from insufficient secretion of steroid hormones (glucocorticoids and mineralocorticoids) from the adrenal glands. In primary hypoadrenocorticism the disease is due to changes to the adrenal cortex, while secondary hypoadrenocorticism refers to deficiency of ACTH, produced in the pituitary gland. The disease can be further classified as typical (glucocorticoid and mineralocorticoid deficiency) with typical electrolyte changes or atypical (only glucocorticoid deficiency with no typical electrolyte changes). The atypical cases often progress to become typical.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000519-9925: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2000 Engelbrecht, Y., Herselman, T., Louw, A., Swart, P. :
Investigation of the primary cause of hypoadrenocorticism in South African Angora goats (Capra aegagrus): A comparison with Boer goats (Capra hircus) and Merino sheep (Ovis aries) Journal of Animal Science 78:371-379, 2000. Pubmed reference: 10709928.
1996 Swart, P., Engelbrecht, Y., Hersehmann, T. :
An investigation of hypo-adrenocorticism in angora goats Endocrine Research 22:563-565, 1996. Pubmed reference: 8969912.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005