OMIA:000519-9685 : Hypoadrenocorticism in Felis catus (domestic cat)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Hypoadrenocorticism, or Addison’s disease, results from insufficient secretion of steroid hormones (glucocorticoids and mineralocorticoids) from the adrenal glands. In primary hypoadrenocorticism the disease is due to changes to the adrenal cortex, while secondary hypoadrenocorticism refers to deficiency of ACTH, produced in the pituitary gland. The disease can be further classified as typical (glucocorticoid and mineralocorticoid deficiency) with typical electrolyte changes or atypical (only glucocorticoid deficiency with no typical electrolyte changes). The atypical cases often progress to become typical.
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2023||Sieber-Ruckstuhl, N.S., Harburger, L., Hofer, N., Kümmerle, C., Müller, C., Riond, B., Hofmann-Lehmann, R., Reusch, C.E., Boretti, F.S. :|
|Clinical features and long-term management of cats with primary hypoadrenocorticism using desoxycorticosterone pivalate and prednisolone. J Vet Intern Med , 2023. Pubmed reference: 36809682. DOI: 10.1111/jvim.16658.|
|2007||Greco, DS. :|
|Hypoadrenocorticism in small animals. Clin Tech Small Anim Pract 22:32-5, 2007. Pubmed reference: 17542195. DOI: 10.1053/j.ctsap.2007.02.005.|
|2002||Smith, S.A., Freeman, L.C., Bagladi-Swanson, M. :|
|Hypercalcemia due to iatrogenic secondary hypoadrenocorticism and diabetes mellitus in a cat Journal of the American Animal Hospital Association 38:41-44, 2002. Pubmed reference: 11804313.|
|2000||Greco, D.S. :|
|Hypoadrenocorticism in dogs and cats Veterinary Medicine 95:468-+, 2000.|
|1999||Parnell, N.K., Powell, L.L., Hohenhaus, A.E., Patnaik, A.K., Peterson, M.E. :|
|Hypoadrenocorticism as the primary manifestation of lymphoma in two cats Journal of the American Veterinary Medical Association 214:1208-+, 1999. Pubmed reference: 10212685.|
|1997||Duesberg, C., Peterson, M.E. :|
|Adrenal disorders in cats Veterinary Clinics of North America - Small Animal Practice 27:321 ff., 1997.|
- Created by Frank Nicholas on 06 Sep 2005