OMIA:000519-9685 : Hypoadrenocorticism in Felis catus (domestic cat)

In other species: dog , horse , goat

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 240200 (trait) , 240300 (trait)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Hypoadrenocorticism, or Addison’s disease, results from insufficient secretion of steroid hormones (glucocorticoids and mineralocorticoids) from the adrenal glands. In primary hypoadrenocorticism the disease is due to changes to the adrenal cortex, while secondary hypoadrenocorticism refers to deficiency of ACTH, produced in the pituitary gland. The disease can be further classified as typical (glucocorticoid and mineralocorticoid deficiency) with typical electrolyte changes or atypical (only glucocorticoid deficiency with no typical electrolyte changes). The atypical cases often progress to become typical.

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000519-9685: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Sieber-Ruckstuhl, N.S., Harburger, L., Hofer, N., Kümmerle, C., Müller, C., Riond, B., Hofmann-Lehmann, R., Reusch, C.E., Boretti, F.S. :
Clinical features and long-term management of cats with primary hypoadrenocorticism using desoxycorticosterone pivalate and prednisolone. J Vet Intern Med , 2023. Pubmed reference: 36809682. DOI: 10.1111/jvim.16658.
2007 Greco, DS. :
Hypoadrenocorticism in small animals. Clin Tech Small Anim Pract 22:32-5, 2007. Pubmed reference: 17542195. DOI: 10.1053/j.ctsap.2007.02.005.
2002 Smith, S.A., Freeman, L.C., Bagladi-Swanson, M. :
Hypercalcemia due to iatrogenic secondary hypoadrenocorticism and diabetes mellitus in a cat Journal of the American Animal Hospital Association 38:41-44, 2002. Pubmed reference: 11804313.
2000 Greco, D.S. :
Hypoadrenocorticism in dogs and cats Veterinary Medicine 95:468-+, 2000.
1999 Parnell, N.K., Powell, L.L., Hohenhaus, A.E., Patnaik, A.K., Peterson, M.E. :
Hypoadrenocorticism as the primary manifestation of lymphoma in two cats Journal of the American Veterinary Medical Association 214:1208-+, 1999. Pubmed reference: 10212685.
1997 Duesberg, C., Peterson, M.E. :
Adrenal disorders in cats Veterinary Clinics of North America - Small Animal Practice 27:321 ff., 1997.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005