OMIA 000527-9615 : Hypomyelinogenesis, congenital in Canis lupus familiaris
In other species: pig , cattle , sheep Mendelian trait/disorder: unknown Considered a defect: yes Cross-species summary: Congenital deficiency of myelin, especially in the cerebellum and brainstem; includes failure of formation of myelin, plus incomplete and delayed myelination of axons. Clinical signs include inability to rise, and severe muscle tremor with periods of spasticity. Also known as oligodendroglial dysplasia.
|2006||Morrison, J.P., Schatzberg, S.J., De Lahunta, A., Ross, J.T., Bookbinder, P., Summers, B.A. :|
|Oligodendroglial dysplasia in two bullmastiff dogs. Vet Pathol 43:29-35, 2006. Pubmed reference: 16407484. DOI: 10.1354/vp.43-1-29.|
- Created by Frank Nicholas on 17 Sep 2014