OMIA:000527-9823 : Hypomyelinogenesis, congenital in Sus scrofa (pig)

In other species: dog , taurine cattle , sheep

Categories: Nervous system phene

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Congenital deficiency of myelin, especially in the cerebellum and brainstem; includes failure of formation of myelin, plus incomplete and delayed myelination of axons. Clinical signs include inability to rise, and severe muscle tremor with periods of spasticity. Also known as oligodendroglial dysplasia.

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000527-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1970 Patterson, D.S.P., Sweasey, D. :
Lipid hexose: phosphorous ratio as an aid to the diagnosis of congenital myelin defects in lambs and piglets Acta Neuropathologia 15:318-326, 1970.
1965 Emerson, J.L., Delez, A.L. :
Cerebellar hypoplasia, hypomyelinogenesis, and congenital tremors of pigs, associated with prenatal hog cholera vaccination of sows Journal of the American Veterinary Medical Association 147:47-54, 1965. Pubmed reference: 5893210.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005