OMIA:000573 : Ciliary dyskinesia, primary, generic
Categories: Respiratory system phene
Possible human homologue (MIM number): 244400 (trait)
Links to MONDO diseases: No links.
Cross-species summary: Congenital defect in functioning of the cilia, which are minute hair-like processes that extend from cell surfaces, beating ryhthmically to move fluid or mucous over the surface. The abnormal functioning results in bronchiectasis (chronic dilation of the bronchi and bronchioles, with associated infection) and sinusitis (inflammation of one or more of the paranasal sinuses). It is also associated with dextrocardia (location of the heart in the right side of the thorax, rather than the usual left side). This phene was renamed in OMIA from 'Kartagener syndrome' to 'Ciliary dyskinesia, primary, generic' [3/6/2022].
- Created by Frank Nicholas on 03 May 2005
- Changed by Imke Tammen2 on 25 Sep 2021
- Changed by Imke Tammen2 on 03 Jun 2022
- Changed by Imke Tammen2 on 29 Oct 2022