OMIA:000576-9796 : Knobbed acrosome in Equus caballus (horse)

In other species: dog , pig , taurine cattle , sheep

Categories: Reproductive system phene

Possibly relevant human trait(s) and/or gene(s) (MIM number): 606165 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: The presence of a protrusion (knob) on the acrosome (cap) of a sperm. Associated with sterility. Also known as Knobbed Acrosome Defect (KAD)

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000576-9796: Online Mendelian Inheritance in Animals (OMIA) [dataset].


1982 Hurtgen, J.P., Johnson, L.A. :
Fertility of stallions with abnormalities of the sperm acrosome Journal of Reproduction and Fertility Supplement 32:15-22, 1982.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005