OMIA 000576-9615 : Knobbed acrosome in Canis lupus familiaris

In other species: horse , pig , cattle , sheep

Possibly relevant human trait(s) and/or gene(s) (MIM number): 606165 (gene)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: The presence of a protrusion (knob) on the acrosome (cap) of a sperm. Associated with sterility. Also known as Knobbed Acrosome Defect (KAD)

Species-specific symbol: KAD


2006 Santos, NR., Krekeler, N., Schramme-Jossen, A., Volkmann, DH. :
The knobbed acrosome defect in four closely related dogs. Theriogenology 66:1626-8, 2006. Pubmed reference: 16584766. DOI: 10.1016/j.theriogenology.2006.02.006.

Edit History

  • Created by Frank Nicholas on 16 Oct 2006