OMIA:000576-9940 : Knobbed acrosome in Ovis aries (sheep)

In other species: dog , horse , pig , taurine cattle

Categories: Reproductive system phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 606165 (gene)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: The presence of a protrusion (knob) on the acrosome (cap) of a sperm. Associated with sterility. Also known as Knobbed Acrosome Defect (KAD)

Species-specific description: There is no evidence for inheritance of this disorder in sheep. It is included here because a similar disorder appears to be inherited in pigs and cattle.

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2012). OMIA:000576-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1998 Soderquist, L. :
Reduced fertility after artificial insemination in a ram with a high incidence of knobbed acrosomes Veterinary Record 143:227-228, 1998. Pubmed reference: 9770767.
1984 Savage, N.G. :
Infertility in a ram associated with a knobbed acrosome abnormality of the spermatozoa Canadian Veterinary Journal 25:126-127, 1984.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 21 May 2012