OMIA 000576-9940 : Knobbed acrosome in Ovis aries
In other species: pig , cattle , horse , dog Possibly relevant human trait(s) and/or gene(s) (MIM number): 606165 (gene) Mendelian trait/disorder: unknown Considered a defect: yes Cross-species summary: The presence of a protrusion (knob) on the acrosome (cap) of a sperm. Associated with sterility. Also known as Knobbed Acrosome Defect (KAD) Species-specific description: There is no evidence for inheritance of this disorder in sheep. It is included here because a similar disorder appears to be inherited in pigs and cattle.
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|1998||Soderquist, L. :|
|Reduced fertility after artificial insemination in a ram with a high incidence of knobbed acrosomes Veterinary Record 143:227-228, 1998. Pubmed reference: 9770767.|
|1984||Savage, N.G. :|
|Infertility in a ram associated with a knobbed acrosome abnormality of the spermatozoa Canadian Veterinary Journal 25:126-127, 1984.|
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 21 May 2012