In other species: domestic cat , horse , pig , rabbit

Categories: Pigmentation phene , Nervous system phene , Digestive / alimentary phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 600155 (trait) , 277580 (trait) , 600501 (trait) , 131244 (gene)

Mendelian trait/disorder: unknown

Disease-related: yes

Cross-species summary: Also known as Hirschsprung disease. A disorder in which the large intestine (caecum, colon and sometimes the rectum) undergoes a large dilation and fills with faecal mass. Associated with incomplete migration of nerve cells to the intestine during embryonic development, resulting in lack of peristalsis and hence a build-up of faecal material.