OMIA:000629-9823 : Megacolon in Sus scrofa (pig)
Categories: Digestive / alimentary phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Also known as Hirschsprung disease. A disorder in which the large intestine (caecum, colon and sometimes the rectum) undergoes a large dilation and fills with faecal mass. Associated with incomplete migration of nerve cells to the intestine during embryonic development, resulting in lack of peristalsis and hence a build-up of faecal material.
Inheritance: No good family data have been published for pigs. However, this disorder is single-locus in some other species.
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2001||Stockhofe-Zurwieden, N., Buijs, R.M., De, Jong, M. :|
|Megacolon in pigs due to segmental colon aganglionosis Deutsche Tierarztliche Wochenschrift 108:267-269, 2001. Pubmed reference: 11449915 .|
|1999||Bassett, J.R., Mann, F.A., Constantinescu, G.M., McClure, R.C. :|
|Subtotal colectomy and ileocolonic anastomosis in a Vietnamese pot-bellied pig with idiopathic megacolon Journal of the American Veterinary Medical Association 215:1640-+, 1999. Pubmed reference: 14567427 .|
|1968||Osborne, J.C., Davis, J.W., Farley, H. :|
|Hirschsprung's disease: a review and report of the entity in a Virginia swine herd Veterinary Medicine and Small Animal Clinician 63:451-453, 1968. Pubmed reference: 5184921 .|
|1955||Kernkamp, H.C.H., Kanning, H.H. :|
|Primary megacolon (Hirschsprung's disease) in swine North American Veterinarian 36:642-643, 1955.|
- Created by Frank Nicholas on 06 Sep 2005