OMIA 000629-9685 : Megacolon in Felis catus

In other species: horse , pig , cattle , rabbit

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 600155 (trait) , 277580 (trait) , 600501 (trait) , 131244 (gene)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Also known as Hirschsprung disease. A disorder in which the large intestine (caecum, colon and sometimes the rectum) undergoes a large dilation and fills with faecal mass. Associated with incomplete migration of nerve cells to the intestine during embryonic development, resulting in lack of peristalsis and hence a build-up of faecal material.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2002 Bertoy, R.W. :
Megacolon in the cat Veterinary Clinics of North America - Small Animal Practice 32:901-+, 2002.
Romanski, K., Slawuta, P., Jankowski, M. :
Megacolon in humans and animals - etiopathogenesis and therapy Medycyna Weterynaryjna 58:832-835, 2002.
1999 Washabau, R.J., Holt, D. :
Pathogenesis, diagnosis, and therapy of feline idiopathic megacolon Veterinary Clinics of North America - Small Animal Practice 29:589-+, 1999.
1998 Eggert, A., Haide, E., Niewerth, B., Prem, J. :
Idiopathic megacolon in a cat [German] Praktische Tierarzt 79:816 ff., 1998.
1996 Washabau, R.J., Stalis, I.H. :
Alterations in colonic smooth muscle function in cats with idiopathic megacolon American Journal of Veterinary Research 57:580-587, 1996. Pubmed reference: 8712528.
1993 Rosin, E. :
Megacolon in Cats - The Role of Colectomy Veterinary Clinics of North America - Small Animal Practice 23:587-594, 1993.
1968 Dietzmann, V.U. :
Uber das Vorkommen des kongenitalen Megakolons (Hirschsprungsches Megakolon) bei der Katz Monatshefte fur Veterinarmedizin 23:349-352, 1968. Pubmed reference: 5692773.
Yoder, J.T., Dragstedt, L.R., Starch, C.J. :
Partial colectomy for correction of megacolon in a cat Veterinary Medicine and Small Animal Clinician 63:1049-1052, 1968. Pubmed reference: 5188481.

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  • Created by Frank Nicholas on 06 Sep 2005